Steroids Ochiza Matenda a Nyamakazi

Zamkati

• Chidule
• Zambiri pazokhudza steroids za RA
• Steroids pakamwa pa RA
• Mlingo
• Majakisoni a Steroid a RA
• Mlingo
• Matenda a steroids a RA
• Kuopsa kogwiritsa ntchito steroids kwa RA
• Zotsatira zoyipa za steroids
• Kutenga

Chidule

Matenda a nyamakazi (RA) ndimatenda osachiritsika omwe amapangitsa ziwalo zazing'ono zamanja ndi mapazi anu kupweteka, kutupa, ndi kuuma. Ndi matenda opita patsogolo omwe alibe mankhwala. Popanda chithandizo, RA imatha kubweretsa kuwonongeka kwa olumikizana ndi kulumala.

Kuzindikira koyambirira ndi chithandizo kumachepetsa zizindikiritso ndikukhalitsa moyo wabwino ndi RA. Chithandizo chimadalira momwe muliri. Ndondomeko zamankhwala nthawi zambiri zimaphatikizapo mankhwala osokoneza bongo (DMARDs) osakanikirana ndi mankhwala osagwiritsa ntchito zotupa (NSAIDs), ndi ma steroids ochepa. Njira zinanso zilipo, kuphatikiza kugwiritsa ntchito maantibayotiki minocycline.

Tiyeni tiwone bwino momwe ma steroids amathandizira pochiza RA.

Zambiri pazokhudza steroids za RA

Steroids amatchedwa corticosteroids kapena glucocorticoids. Ndiwo mankhwala opangidwa ofanana ndi cortisol, mahomoni omwe adrenal glands amapanga mwachilengedwe. Mpaka zaka 20 zapitazo, ma steroids anali njira yovomerezeka ya RA.

Koma miyezo imeneyi idasintha pomwe zotsatira zoyipa za steroids zidayamba kudziwika ndipo mitundu yatsopano ya mankhwala idapangidwa. Malangizo aposachedwa a RA a The American College of Rheumatology tsopano amalangiza madotolo kuti azigwiritsa ntchito ma steroid ochepa kwambiri kwakanthawi kochepa.

Steroid imatha kutengedwa pakamwa, jekeseni, kapena kuyikidwa m'mutu.

Steroids pakamwa pa RA

Steroids pakamwa amabwera mapiritsi, kapisozi, kapena mawonekedwe amadzimadzi. Amathandizira kuchepetsa kuchuluka kwa kutupa mthupi lanu komwe kumapangitsa mafupa anu kutupa, kuuma, komanso kupweteka. Amathandizanso kuwongolera dongosolo lanu lodzitchinjiriza kuti muchepetse ziwopsezo. Pali umboni wina woti ma steroids amachepetsa kuwonongeka kwa mafupa.

Mitundu yodziwika ya ma steroids yomwe imagwiritsidwa ntchito ndi RA ndi awa:

• prednisone (Deltasone, Sterapred, Phula Pred)
• hydrocortisone (Cortef, A-Hydrocort)
• chibadul
• dexamethasone (Dexpak Taperpak, Decadron, Hexadrol)
• methylprednisolone (Depo-Medrol, Medrol, Methacort, Depopred, Predacorten)
• wochita
• dexamethasone (Decadron)
• betamethasone

Prednisone ndiye steroid yemwe amagwiritsidwa ntchito kwambiri mu RA.

Mlingo

Mlingo wochepa wa steroids wamlomo amatha kulembedwa koyambirira kwa RA, limodzi ndi ma DMARD kapena mankhwala ena. Izi ndichifukwa ma DMARD amatenga masabata 8-12 kuti awonetse zotsatira. Koma ma steroids amachita mwachangu, ndipo mudzawona zotsatira zake m'masiku ochepa. Steroids nthawi zina amatchedwa "njira yothandizira mlatho."

Mankhwala ena atayamba kugwira ntchito, ndikofunikira kuchotsa ma steroids. Izi zimachitika pang'onopang'ono, pang'ono ndi pang'ono. Kujambula kumathandiza kupewa zizindikiritso zakutha.

Mlingo wamba wa prednisone ndi 5 mpaka 10 mg tsiku lililonse. Ndikulimbikitsidwa kuti musamwe mopitilira 10 mg patsiku la prednisone. Itha kuperekedwa pamiyeso iwiri ya iliyonse.

Nthawi zambiri, ma steroids amatengedwa m'mawa mukadzuka. Apa ndipamene ma steroids amthupi anu amayamba kugwira ntchito.

Zakudya zowonjezera tsiku ndi tsiku za calcium () ndi vitamini D () zimakhala ndi ma steroids.

Mankhwala apamwamba a steroids atha kugwiritsidwa ntchito mu RA pakakhala zovuta zina.

Kuunikanso kwa RA mu 2005 kunapeza kuti 20 mpaka 40% ya anthu omwe atangopezeka ndi RA anali kugwiritsa ntchito ma steroids. Kuwunikiraku kunapezanso kuti mpaka 75 peresenti ya anthu omwe ali ndi RA adagwiritsa ntchito ma steroids nthawi ina.

Nthawi zina, anthu omwe ali ndi RA (omwe nthawi zina amatchedwa kulepheretsa) RA amadalira ma steroids nthawi yayitali kuti achite ntchito za tsiku ndi tsiku.

Majakisoni a Steroid a RA

Steroids atha kubayidwa bwino ndi dokotala wanu m'malo amalo komanso malo owazungulira kuti amve kupweteka komanso kutupa. Izi zitha kuchitika pamene mukusunga mankhwala ena omwe munapatsidwa.

American College of Rheumatology inanena kuti kumayambiriro kwa RA, jakisoni wa steroid m'malo olumikizidwa kwambiri amatha kupereka mpumulo wamba komanso nthawi zina. Izi zitha kukhala zazikulu, koma sizikhalitsa.

Nthawi zina, jakisoni wa steroid wakhala akuchepetsa kukula kwa mitsempha ya RA. Izi zimapereka njira ina yochitira opaleshoni.

Ndikulimbikitsidwa kuti jakisoni mu cholumikizira chomwecho asachite kangapo kamodzi miyezi itatu.

Mlingo

Ma steroids omwe amagwiritsidwa ntchito jekeseni ndi methylprednisolone acetate (Depo-Medrol), triamcinolone hexacetonide, ndi triamcinolone acetonide.

Dokotala wanu amathanso kugwiritsa ntchito mankhwala oletsa ululu pakakupatsani jakisoni wa steroid.

Mlingo wa methylprednisolone nthawi zambiri umakhala 40 kapena 80 mg pa mililita. Mlingowu umasiyana malinga ndi kukula kwa cholumikizira chomwe chikujambulidwa. Mwachitsanzo, bondo lanu lingafune mulingo wokulirapo, mpaka 80 mg. Koma chigongono chanu chimangofunika 20 mg yokha.

Matenda a steroids a RA

Mankhwala otchedwa steroids, omwe amagulitsidwa mobwerezabwereza ndi mankhwala, nthawi zambiri amagwiritsidwa ntchito ndi anthu omwe ali ndi nyamakazi kuti athe kupweteka. Koma ma topical steroids sakuvomerezeka (kapena kutchulidwa) mu malangizo a American College of Rheumatology RA.

Kuopsa kogwiritsa ntchito steroids kwa RA

Kugwiritsa ntchito Steroid mu chithandizo cha RA ndichifukwa cha zomwe zalembedwa zomwe zikuwopsa.

Zowopsa zazikulu ndizo:

• Matenda amtima: Kuwunikanso kwa 2013 kwa anthu omwe amapezeka ndi RA ndikumwa ma steroids adapeza kuti 68 peresenti idawopsa pachiwopsezo cha mtima. Kafukufukuyu adakhudza anthu 8,384 omwe amapezeka ndi RA pakati pa 1997 ndi 2006. Mlingo uliwonse wa 5 mg patsiku ukuwonjezeka pamlingo wowonjezeredwa pachiwopsezo.
• Kufooka kwa mafupa: Kutengeka ndi kugwiritsa ntchito steroid kwa nthawi yayitali ndi chiopsezo chachikulu.
• Imfa: Kafukufuku wina akuwonetsa kuti anthu akhoza kufa ndi kugwiritsa ntchito steroid.
• Kupunduka
• Matenda a shuga

Zowopsa zimawonjezeka ndikumagwiritsa ntchito nthawi yayitali komanso mlingo waukulu.

Zotsatira zoyipa za steroids

Zotsatira zoyipa zogwiritsidwa ntchito ndi steroid mu chithandizo cha RA ndi monga:

• chiopsezo chowonjezeka cha matenda a bakiteriya kapena ma virus
• kunenepa
• nkhope yozungulira, yotchedwanso "nkhope ya mwezi"
• shuga wochuluka wamagazi
• kuthamanga kwa magazi
• kusokonezeka kwamaganizidwe, kuphatikiza kukhumudwa ndi nkhawa
• kusowa tulo
• kutupa kwa mwendo
• kuvulaza kosavuta
• kufalikira kwakukulu kwa mafupa
• kusakwanira kwa adrenal
• adachepetsa kuchepa kwa mafupa patatha miyezi isanu mutadutsa 10 mg prednisone

Zotsatira za jakisoni wa Steroid ndizochepa ndipo nthawi zambiri zimakhala zosakhalitsa. Izi zikuphatikiza:

• khungu kuyabwa
• thupi lawo siligwirizana
• kupatulira khungu

Funsani dokotala wanu ngati zovuta zikukuvutitsani kapena zimachitika mwadzidzidzi. Onetsetsani shuga lanu lamagazi ngati muli ndi matenda ashuga.

Kutenga

Steroids pamlingo wochepa akhoza kukhala gawo la njira yothandizira RA kuti athetse zizindikilo. Amagwira ntchito mwachangu kuti athetse kutupa ndi kupweteka. Koma muyenera kusamala mosamala za zoopsa zodziwika za kugwiritsa ntchito steroid, ngakhale pamlingo wochepa.

Werengani zonse za chithandizo chamankhwala, kuphatikizapo biologics ndi antibiotic minocycline. Ganizirani zopindulitsa ndi zochepa za mankhwala ndi mankhwala.Kambiranani zomwe mungachite ndi dokotala wanu, ndipo onetsetsani kuti mafunso anu onse ayankhidwa.

Koposa zonse, chithandizo cha RA chimafuna kuti musamale.