Stiff Munthu Matenda

Zamkati

• Kodi stiff person syndrome ndi chiyani?
• Kodi Zizindikiro Za Matenda Aanthu Olimba Ndi Zotani?
• Nchiyani chimayambitsa matenda owuma?
• Kodi matenda ouma mtima amapezeka bwanji?
• Kodi matenda owuma amathandizidwa bwanji?
• Kodi chiyembekezo cha matenda ouma mtima ndi otani?

Kodi stiff person syndrome ndi chiyani?

Stiff person syndrome (SPS) ndimatenda amthupi okhaokha. Monga mitundu ina yamatenda amitsempha, SPS imakhudza ubongo wanu ndi msana (dongosolo lamanjenje).

Matenda omwe amabwera chifukwa chodzitchinjiriza thupi amachitika pamene chitetezo chamthupi chanu chimazindikiritsa molakwika kuti matupi abwinobwino ndi owopsa ndikuwapweteka.

SPS ndiyosowa. Zingakhudze kwambiri moyo wanu popanda chithandizo choyenera.

Kodi Zizindikiro Za Matenda Aanthu Olimba Ndi Zotani?

Makamaka, SPS imayambitsa kuuma kwa minofu. Zizindikiro zoyambirira zimaphatikizapo:

• kuuma kwamiyendo
• minofu yolimba m thunthu
• kukhazikika pamavuto olimba kumbuyo (izi zitha kukupangitsani kusaka)
• kupweteka kwa minofu
• zovuta kuyenda
• zovuta, monga kuzindikira kuwala, phokoso, ndi mawu
• thukuta kwambiri (hyperhidrosis)

Spasms chifukwa cha SPS imatha kukhala yamphamvu kwambiri ndipo imatha kukupangitsani kugwa ngati mukuyimirira. Spasms nthawi zina imakhala yolimba yokwanira kuthyola mafupa. Spasms amakhala ovuta kwambiri mukakhala ndi nkhawa kapena kukwiya. Spasms amathanso kuyambitsidwa ndikusunthira mwadzidzidzi, phokoso lalikulu, kapena kukhudzidwa.

Mukakhala ndi SPS, mutha kukhalanso ndi nkhawa kapena nkhawa. Izi zitha kuyambitsidwa ndi zizindikilo zina zomwe mwina mukukumana nazo kapena kuchepa kwa ma neurotransmitters muubongo.

Zomwe zingayambitse kukhumudwa kwamaganizidwe zimatha kuchuluka pamene SPS ikupita. Mutha kuzindikira kuti ma spamu amakula mukakhala pagulu. Izi zitha kubweretsa nkhawa yakukhala pagulu.

M'magawo amtsogolo a SPS, mutha kukhala ndi kuwuma kwa minofu ndi kuuma.

Kuuma kwa minofu kungafalikire mbali zina za thupi lanu, monga nkhope yanu. Izi zitha kuphatikizira minofu yogwiritsidwa ntchito pakudya komanso poyankhula. Minofu yokhudzana ndi kupuma imathanso kukhudzidwa ndikupangitsa mavuto owopsa moyo kupuma.

Chifukwa cha kupezeka kwa ma amphiphysin antibodies, SPS imatha kuyika anthu ena pachiwopsezo cha khansa zina, kuphatikiza:

• bere
• m'matumbo
• mapapo

Anthu ena omwe ali ndi SPS amatha kukhala ndi zovuta zina, monga:

• matenda ashuga
• mavuto a chithokomiro
• kuchepa kwa magazi m'thupi
• vitiligo

Nchiyani chimayambitsa matenda owuma?

Zomwe zimayambitsa SPS sizikudziwika. Mwina ndi chibadwa.

Muthanso kukhala pachiwopsezo chowonjezeka cha matendawa ngati inu kapena wina m'banja mwanu ali ndi matenda amtundu wina. Izi zikuphatikiza:

• lembani 1 ndi 2 shuga
• kuchepa kwa magazi m'thupi
• nyamakazi
• chithokomiro
• vitiligo

Pazifukwa zosadziwika, matenda omwe amadzimadzimadzimadzimodzi amalimbana ndimatenda athanzi mthupi. Ndi SPS, zotupa muubongo ndi msana zimakhudzidwa. Izi zimayambitsa zizindikiro kutengera minofu yomwe yaukiridwa.

SPS imapanga ma antibodies omwe amalimbana ndi mapuloteni mu ma neuron aubongo omwe amayang'anira kusuntha kwa minofu. Izi zimatchedwa ma glutamic acid decarboxylase antibodies (GAD).

SPS nthawi zambiri imachitika mwa achikulire azaka zapakati pa 30 ndi 60. Ndiwonso kawiri kuposa azimayi poyerekeza ndi amuna.

Kodi matenda ouma mtima amapezeka bwanji?

Kuti mupeze SPS, dokotala wanu ayang'ana mbiri yanu yazachipatala ndikuyeserera.

Kuyesedwa ndikofunikanso. Choyamba, kuyesa magazi kumatha kuperekedwa kuti mupeze ma antibodies a GAD. Aliyense amene ali ndi SPS alibe ma antibodies awa. Komabe, mpaka 80 peresenti ya anthu omwe ali ndi SPS amatero.

Dokotala wanu akhoza kuyitanitsa mayeso owunika otchedwa electromyography (EMG) kuti ayese zamagetsi zamagetsi. Dokotala wanu amathanso kuyitanitsa MRI kapena lumbar puncture.

SPS imatha kupezeka ndi khunyu. Nthawi zina amalakwitsa chifukwa cha zovuta zina zamitsempha, monga multiple sclerosis (MS) ndi matenda a Parkinson.

Kodi matenda owuma amathandizidwa bwanji?

Palibe mankhwala a SPS. Komabe, mankhwala alipo kuti akuthandizeni kuthana ndi matenda anu. Chithandizo chitha kupewanso vutoli kukulirakulirakulirabe. Minyewa yolimba imatha kuthandizidwa ndi mankhwala amodzi kapena angapo otsatirawa:

• Baclofen, chotakasuka minofu.
• Benzodiazepines, monga diazepam (Valium) kapena clonazepam (Klonopin). Mankhwalawa amachepetsa minofu yanu ndikuthandizani ndi nkhawa. Mlingo waukulu wa mankhwalawa umagwiritsidwa ntchito kuthana ndi mitsempha ya minofu.
• Gabapentin ndi mtundu wa mankhwala omwe amagwiritsidwa ntchito kupweteka kwa mitsempha ndi kupweteka.
• Opumitsa minofu.
• Mankhwala opweteka.
• Zamgululi ndi mankhwala oletsa kulanda.

Anthu ena omwe ali ndi SPS adakhalanso ndi mpumulo wazizindikiro ndi:

• Autologous tsinde cell kumuika ndiyo njira yomwe magazi anu ndi mafupa am'mafupa amasonkhanitsidwa ndikuwonjezeka musanabwerere m'thupi lanu. Ichi ndi chithandizo choyesera chomwe chimangoganiziridwa pambuyo poti mankhwala ena alephera.
• Mitsempha yoteteza thupi ku immunoglobin imatha kuchepetsa kuchuluka kwa ma antibodies omwe amayambitsa matenda athanzi.
• Plasmapheresis ndi njira yomwe m'magazi anu amagulitsidwa ndi plasma yatsopano kuti muchepetse kuchuluka kwa ma antibodies mthupi.
• Ma immunotherapies ena monga rituximab.

Ma anti-depressants, monga serotonin reuptake inhibitors (SSRIs) osankhidwa amatha kuthandizira kukhumudwa komanso kuda nkhawa. Zoloft, Prozac, ndi Paxil ndi ena mwazomwe dokotala angakuuzeni. Kupeza mtundu woyenera nthawi zambiri kumayesedwa.

Kuphatikiza pa mankhwala, dokotala akhoza kukutumizirani kwa othandizira. Chithandizo cha thupi chokha sichingathe kuchiza SPS. Komabe, zolimbitsa thupi zitha kuthandiza kwambiri ndi:

• kukhala ndi thanzi labwino
• kuyenda
• kudziyimira pawokha
• ululu
• kaimidwe
• ntchito ya tsiku ndi tsiku
• mayendedwe osiyanasiyana

Kutengera momwe matenda anu alili oopsa, othandizira anu azakutsogolerani pakuyenda komanso kupumula. Mothandizidwa ndi othandizira, mutha kuyesetsabe kusuntha kwanu.

Kodi chiyembekezo cha matenda ouma mtima ndi otani?

Ngati mukukhala ndi vutoli, mumakonda kugwa chifukwa chosowa kukhazikika komanso kusinkhasinkha. Izi zitha kukulitsa chiopsezo chovulala kwambiri komanso ngakhale kulumala kwamuyaya.

Nthawi zina, SPS imatha kupita patsogolo ndikufalikira mbali zina za thupi lanu.

Palibe mankhwala a SPS. Komabe, mankhwala alipo kuti akuthandizeni kuthana ndi matenda anu. Maganizo anu onse amatengera momwe mapulani anu amathandizira.

Aliyense amalandira chithandizo mosiyanasiyana. Anthu ena amalabadira bwino mankhwala ndi chithandizo chamankhwala, pomwe ena sangayankhe bwino.

Kambiranani ndi dokotala za matenda anu. Ndikofunikira kwambiri kukambirana zachilendo zatsopano zomwe mukukumana nazo kapena ngati simukuwona kusintha kulikonse. Izi zitha kuwathandiza kusankha njira yamankhwala yomwe ingakuthandizeni kwambiri.