Chithandizo cha Psoriasis

Zamkati

• Matenda apakhungu a psoriasis
• Mavitamini D ofanana
• Mafuta a malasha kapena mafuta odzola
• Shampoo zosalala
• Salicylic acid ndi lactic acid
• Njira zothandizira psoriasis
• Methotrexate
• Cyclosporine
• PDE4 zoletsa
• Retinoids
• Hydroxyurea
• Mankhwala osokoneza bongo (biologics)
• Thioguanine
• Kugwiritsa ntchito mankhwala osokoneza bongo
  
• Phototherapy (mankhwala opepuka)
• Dzuwa
• Kujambula kwa UVB
• Chithandizo cha Goeckerman
• Chotupitsa laser
• Photochemotherapy, kapena psoralen kuphatikiza ultraviolet A (PUVA)
• Laser yopaka utoto

Chidule

Kuchiza psoriasis kumafunikira njira zingapo zosiyanasiyana. Izi zingaphatikizepo kusintha kwa moyo, zakudya, phototherapy, ndi mankhwala. Chithandizo chimadalira kuopsa kwa zizindikilo zanu, msinkhu wanu, thanzi lanu lonse, ndi zina.

Palibe mankhwala a psoriasis, kotero madokotala nthawi zambiri amayesa njira zingapo asanapeze chithandizo choyenera kwa inu.

Chithandizo cha psoriasis chimadalira izi:

• kuuma kwa psoriasis yanu
• kuchuluka kwa thupi lanu lomwe lakhudzidwa
• mtundu wanu wa psoriasis
• khungu lanu limayankha bwino kuchipatala

Mankhwala ambiri odziwika amafunikira kuti athe kuchiza matenda. Amayesa kukhazika khungu loyabwa komanso lotuluka ndikuchepetsa kuchepa. Kugwiritsa ntchito zothira mafuta pafupipafupi (OTC) mukatha kusamba komanso kusamba kungathandize kuti chinyezi chikhale pakhungu kuti zisamayende. Koma sichitha kutupa komwe kumayambitsa.

Madokotala othandiza khungu la anthu amalimbikitsanso kuti anthu omwe ali ndi psoriasis azigwiritsa ntchito sopo wopanda mafuta onunkhira komanso mankhwala opanda utoto, zotsekemera, komanso zonunkhira kuti khungu lisakhumudwe kwambiri.

Apa, tidzafotokozera zamankhwala ochiritsira a psoriasis, kuyambira kuchipatala choyamba monga mafuta am'mutu mpaka gulu latsopano la mankhwala otchedwa biologics.

Matenda apakhungu a psoriasis

Mankhwala ogwiritsidwa ntchito pakhungu amatchedwa mankhwala apakhungu. Zikuphatikizapo:

• mafuta
• mafuta onunkhira
• mafuta odzola
• Angelo

Nthawi zambiri amakhala mzere woyamba wa chithandizo cha anthu omwe ali ndi psoriasis wofatsa mpaka pang'ono. Nthawi zina, amagwiritsidwa ntchito limodzi ndi mtundu wina wa chithandizo.

Mafuta a Corticosteroid okhala ndi mafuta ndi mankhwala omwe amapezeka kwambiri ku psoriasis. Mankhwala ochepetsawa a steroid amagwiritsira ntchito kuwongolera kupanga kwambiri kwa khungu ndikuchepetsa khungu. Komabe, ma corticosteroids ena amaphatikizapo ma steroids amphamvu omwe atha kukulitsa zizindikilo zanu. Dokotala wanu adziwa mphamvu yolondola yochepetsera matenda anu, m'malo mowonjezera.

Matenda a retinoids ndi mtundu wina wamankhwala opangidwa kuchokera ku vitamini A. Amagwira ntchito kuti azolowere kukula m'maselo akhungu. Izi zimachepetsa kutupa. Ngakhale sizimathamanga ngati mafuta a corticosteroid, ma topical retinoids amakhala ndi zovuta zochepa. Amayi omwe ali ndi pakati kapena atha kukhala ndi pakati sayenera kugwiritsa ntchito izi chifukwa cha chiopsezo chobadwa nako.

Mavitamini D ofanana

Izi ndi mitundu ya vitamini D yomwe imachedwetsa kukula kwa khungu. Dokotala wanu amatha kuwapatsa mankhwalawa okha kapena ndi mankhwala ena kuti athe kuchiza psoriasis yochepa. Zikuphatikizapo:

• calcipotriene (Dovonex)
• calcitriol (Rocaltrol)

Mafuta a malasha kapena mafuta odzola

Phula la malasha ndi mankhwala akale kwambiri a psoriasis. Zimapangidwa kuchokera kuzinthu zopangidwa ndi mafuta. Zida zamafuta zamafuta zimachepetsa makulidwe, kuyabwa, ndi kutupa. Kuwonjezeka kwakukulu kumapezeka mwa mankhwala.

Mafuta awa ali ndi zovuta zina, komabe. Phula la malasha ndi losokoneza, ndipo limatha kuipitsa zovala ndi zofunda. Ikhozanso kukhala ndi fungo lamphamvu komanso losasangalatsa.

Shampoo zosalala

Mankhwala opatsirana mankhwala opatsirana pogwiritsa ntchito mankhwala osokoneza bongo amapezeka ndi dokotala kuti akuthandizeni psoriasis pamutu panu.

Salicylic acid ndi lactic acid

Ziphuphu zonsezi zimalimbikitsa kupopera maselo akhungu lakufa, zomwe zimachepetsa kukula. Zitha kugwiritsidwanso ntchito limodzi ndi mankhwala ena. Zilipo mu OTC ndi mitundu ya mankhwala.

Njira zothandizira psoriasis

Mankhwala akuchipatala atha kuthana ndi kufalikira kwa psoriasis polimbana ndi kutupa.

Madokotala nthawi zambiri amakonda kugwiritsa ntchito mankhwala otsika kwambiri omwe amafunikira kuti athetse zizindikilo. Amayamba ndi chithandizo cham'mutu nthawi zambiri. Khungu likayamba kugonjetsedwa ndipo silimayankhanso kuchipatala chimodzi, chithandizo champhamvu chimatha kugwiritsidwa ntchito.

Dokotala wanu akhoza kukupatsani mankhwala akumwa kapena ojambulidwa ngati psoriasis yanu ndi yovuta kwambiri kapena siyiyankha pazosankha zam'mutu. Ambiri mwa mankhwalawa amakhala ndi zotsatirapo, motero madotolo amangogwiritsa ntchito milandu yovuta kapena yosalekeza.

Methotrexate

Methotrexate imachepetsa kupanga kwa khungu ndipo imalepheretsa chitetezo cha mthupi. Madokotala nthawi zambiri amapereka izi kwa anthu omwe ali ndi psoriasis yochepa. Ndi imodzi mwazithandizo zothandiza kwambiri kwa anthu omwe ali ndi erythrodermic psoriasis kapena pustular psoriasis. Posachedwa, madotolo ayamba kuwalemba kuti azithandizanso psoriatic nyamakazi.

Zotsatira zoyipa zimaphatikizapo:

• kusowa chilakolako
• kutopa
• kukhumudwa m'mimba

Cyclosporine

Cyclosporine ndi mankhwala othandiza kwambiri opangidwa kuti athane ndi chitetezo chamthupi. Madokotala nthawi zambiri amapereka mankhwalawa kwa anthu omwe ali ndi vuto la psoriasis chifukwa amachepetsa chitetezo chamthupi.

Madokotala ambiri amangopatsanso mankhwalawa kwa nthawi yayitali chifukwa chakuwopsa kwa kuthamanga kwa magazi. Mukalandira mankhwalawa, mufunika kuyezetsa magazi pafupipafupi ndikuwunika kuthamanga kwa magazi kuti muwone zovuta zomwe zingabwere.

PDE4 zoletsa

Mankhwala amodzi okha, otchedwa apremilast (Otezla), omwe amapezeka mgulu latsopanoli la mankhwala a psoriasis. Sizimamveka bwino momwe apremilast imagwirira ntchito pochiza psoriasis. Amaganiziridwa kuti amagwira ntchito pochepetsa kuyankha kwa thupi lanu pakatupa.

Retinoids

Retinoids amapangidwa kuchokera ku mavitamini A. Amachiza psoriasis yochepa pochepetsa kupanga khungu. Dokotala wanu angakuuzeni kuti mugwiritse ntchito mankhwalawa mopepuka.

Monga mankhwala ena amtundu uliwonse, awa ali ndi zovuta zina zoyipa. Dokotala wanu amatha kuyitanitsa kuyezetsa magazi pafupipafupi kuti akafufuze cholesterol, yomwe ndimavuto ambiri kwa anthu omwe amamwa mankhwalawa. Retinoids amathanso kuyambitsa zofooka zobadwa. Amayi omwe ali ndi pakati kapena akufuna kukhala ndi pakati sayenera kumwa mankhwalawa.

Retinoid yokhayo yovomerezeka ndi FDA yothandizira psoriasis ndi acitretin (Soriatane).

Hydroxyurea

Hydroxyurea ndi gulu la mankhwala otchedwa antimetabolites. Zimaganiziridwa kuti zimagwira ntchito poletsa kubwereza kwa DNA. Itha kugwiritsidwa ntchito ndi phototherapy, koma siyothandiza ngati cyclosporine ndi methotrexate.

Zotsatira zoyipa zimaphatikizapo magulu ofiira a magazi omwe ndi otsika kwambiri (kuchepa magazi) komanso kuchepa kwa maselo oyera am'magazi. Amayi omwe ali ndi pakati kapena akukonzekera kutenga pakati sayenera kumwa hydroxyurea chifukwa cha chiopsezo cha kubadwa ndi kutaya padera.

Mankhwala osokoneza bongo (biologics)

Biologics ndi mankhwala atsopano omwe amalimbana ndi chitetezo cha mthupi lanu. Mankhwalawa amaperekedwa ndi jakisoni kapena kulowetsedwa mkati mwa mtsempha (IV). Madokotala nthawi zambiri amawapatsa mankhwalawa kwa anthu omwe ali ndi psoriasis yochepa kwambiri omwe sanayankhe kuchipatala.

Ma biologics ovomerezeka kuchiza psoriasis ndi awa:

• adalimumab (Humira)
• etanercept (Enbrel)
• chitsimikizo (Cimzia)
• infliximab (Kutulutsa)
• ustekinumab (Stelara)
• secukinumab (Cosentyx)
• ixekizumab (Taltz)
• brodalumab (Siliq)
• guselkumab (Tremfya)
• tildrakizumab (Ilumya)
• risankizumab (Skyrizi)

Ma biosimilars amapezekanso kumene, omwe amafanana ndi mankhwala amtundu wa biologic, koma osati mtundu weniweni. Amayembekezeredwa kukhala ndi zovuta zofananira monga mankhwala wamba. Pakadali pano pali biosimilars za infliximab ndi etanercept.

Thioguanine

Thioguanine imagwiritsidwa ntchito ngati mankhwala pochiza psoriasis. Ngakhale sagwira ntchito ngati methotrexate kapena cyclosporine, thioguanine ili ndi zovuta zochepa. Izi zimapangitsa kukhala njira yabwino kwambiri yothandizira. Komabe, zimatha kupangitsanso kupunduka. Amayi omwe ali ndi pakati kapena akukonzekera kutenga pakati ayenera kupewa kutenga.

Kugwiritsa ntchito mankhwala osokoneza bongo

• Kugwiritsa ntchito mankhwala osokoneza bongo kumatanthauza kuti mankhwala omwe avomerezedwa ndi FDA pacholinga chimodzi amagwiritsidwa ntchito pazinthu zina zomwe sizinavomerezedwe. Komabe, dokotala amatha kugwiritsabe ntchito mankhwalawa pazifukwa izi. Izi ndichifukwa choti a FDA amayang'anira kuyesa ndi kuvomereza mankhwala, koma osati momwe madotolo amagwiritsira ntchito mankhwala pochizira odwala awo. Chifukwa chake, adotolo amatha kukupatsani mankhwala ngakhale akuganiza kuti ndi bwino kuti musamalire.

Phototherapy (mankhwala opepuka)

Phototherapy ndi njira yomwe khungu limayang'aniridwa mosamala ndi kuwala kwachilengedwe kapena kopanga za ultraviolet (UV).

Ndikofunika kukambirana za phototherapy ndi dermatologist musanadziwonetse nokha pamiyeso yayikulu ya kuwala kwa UV. Kujambula zithunzi kwa nthawi yayitali kumalumikizidwa ndi kuchuluka kwa khansa yapakhungu, makamaka khansa ya pakhungu. Musayese kudzichitira nokha ndi bedi lofufuta kapena sunbathing.

Dzuwa

Gwero lenileni la kuwala kwa UV ndi dzuwa. Zimapanga kuwala kwa UVA. Kuwala kwa UV kumachepetsa kupanga ma T ndipo pamapeto pake kumapha ma cell a T omwe atsegulidwa. Izi zimachedwetsa kuyankha kotupa komanso kuchuluka kwa khungu.

Kuwonetsera pang'ono kwa kuwala pang'ono kwa dzuwa kumatha kusintha psoriasis. Komabe, kutentha kwambiri kwa dzuwa kapena kutentha kwa nthawi yayitali kumatha kukulitsa zizindikilo. Zitha kupanganso kuwonongeka kwa khungu ndipo zitha kukulitsa mwayi wokhala ndi khansa yapakhungu.

Kujambula kwa UVB

Pazakudya zochepa za psoriasis, mankhwala opepuka opangira kuwala kwa UVB amatha kugwiritsidwa ntchito.Chifukwa mabokosi owala otulutsa UVB amagwiritsidwa ntchito pafupipafupi pa mankhwala amtunduwu, zigamba kapena zigawo zing'onozing'ono za khungu zimatha kuchiritsidwa, m'malo mowonetsa thupi lonse.

Zotsatira zoyipazi zimaphatikizapo kuyabwa, khungu louma komanso kufiira m'malo omwe amathandizidwa.

Chithandizo cha Goeckerman

Kuphatikiza chithandizo cha UVB ndi mankhwala amakala kumapangitsa kuti mankhwala awiriwa azigwira bwino ntchito kuposa mankhwala okha. Phula lamakala limapangitsa khungu kulandila kuwala kwa UVB. Mankhwalawa amagwiritsidwa ntchito pazochitika zochepa.

Chotupitsa laser

Mankhwala a Laser ndi chitukuko cholonjeza pochiza psoriasis wofatsa mpaka pang'ono. Lasers imatha kuwunikira kuwala kwa UVB pamiyeso yama psoriatic osakhudza khungu loyandikana nalo. Koma zitha kukhala zothandiza kuthana ndi zigamba zazing'ono chifukwa laser silingakwaniritse malo akulu.

Photochemotherapy, kapena psoralen kuphatikiza ultraviolet A (PUVA)

Psoralen ndi mankhwala owunikira opepuka omwe atha kuphatikizidwa ndi UVA light therapy ngati chithandizo cha psoriasis. Odwala amamwa mankhwalawo kapena amathira mafuta pakhungu ndikulowetsa bokosi lowala la UVA. Mankhwalawa ndi owopsa ndipo nthawi zambiri amangogwiritsidwa ntchito kwa odwala omwe ali ndi vuto la psoriasis.

Laser yopaka utoto

Dokotala wanu angakulimbikitseni laser ya pulsed ngati mankhwala ena sapambana. Izi zimawononga mitsempha yaying'ono yamagazi m'malo ozungulira ma psoriasis, kudula magazi ndikuchepetsa kukula kwa khungu m'derali.