Kodi leukocytoclastic vasculitis, zomwe zimayambitsa, zizindikiro ndi chithandizo

Zamkati

• Zomwe zimayambitsa leukocytoclastic vasculitis
• Zizindikiro zazikulu
• Momwe mankhwalawa amachitikira

Leukocytoclastic vasculitis, yomwe imadziwikanso kuti hypersensitivity vasculitis kapena chotengera chaching'ono chotchedwa vasculitis, chimafanana ndi kutukusira kwa mitsempha yamagazi yomwe imatha kuchitika chifukwa cha kutupa, matenda kapena matenda amthupi okhaokha, zomwe zimabweretsa mawanga ofiira makamaka pamiyendo, ntchafu ndi m'mimba

Kuzindikira mtundu wa vasculitis kumapangidwa poganizira zomwe zimaperekedwa ndi munthuyo komanso zotsatira za mayeso a labotale omwe dokotala angamupemphe. Nthawi zambiri, zizindikiro za leukocytoclastic vasculitis zimatha pakatha miyezi ingapo, komabe kungakhale kofunikira kugwiritsa ntchito mankhwala ena monga antihistamines kapena corticosteroids kutengera kukula kwa vasculitis.

Zomwe zimayambitsa leukocytoclastic vasculitis

Mtundu wa vasculitis umatha kukhala ndi zifukwa zingapo ndipo nthawi zambiri umakhala wokhudzana ndi zinthu zomwe zimalimbikitsa kusintha kwa chitetezo chamthupi. Izi ndichifukwa choti amakhulupirira kuti zizindikilo za leukocytoclastic vasculitis zimachitika chifukwa chokhazikitsidwa ndi malo achitetezo am'magazi m'mitsempha yaying'ono, zomwe zimapangitsa kutupa.

Chifukwa chake, zoyambitsa zazikulu zokhudzana ndi kukula kwa mtundu uwu wa vasculitis ndi izi:

• Matupi awo sagwirizana ndi mankhwala ena monga maantibayotiki, anti-steroidal anti-inflammatory drugs, beta-blockers, warfarin ndi metformin;
• Matupi awo sagwirizana ndi zakudya zina kapena zowonjezera zakudya;
• Matenda ndi mabakiteriya, mavairasi kapena majeremusi, omwe amatenga kachilombo kawirikawiri omwe amakhala Streptococcus pyogenes, Mycobacterium chifuwa chachikulu, Staphylococcus aureus, Chlamydia trachomatis, Neisseria gonorrhoeae, mavairasi a hepatitis B ndi C ndi HIV;
• Matenda osokoneza bongo monga nyamakazi, systemic lupus erythematosus ndi matenda a Sjogren;
• Matenda opatsirana otupa monga matenda a Crohn ndi ulcerative colitis, mwachitsanzo;
• Zosintha zoyipa monga zotupa, lymphoma, khansa ya m'magazi ndi myelodysplastic syndrome.

Kuzindikira kwa leukocytoclastic vasculitis kumapangidwa ndi dokotala, angiologist, rheumatologist kapena dermatologist kudzera pakuwunika koyambirira kwa zizindikilo ndi zomwe munthuyo wachita. Kuphatikiza apo, akufunsidwanso ndi adotolo kuti apange mayeso a labotale omwe amathandiza kuti azindikire kusiyanasiyana, monga kuwerengetsa magazi, VSH, mayeso omwe amayesa kuyesa kwa chiwindi ndi impso ndi mkodzo.

Pofuna kutsimikizira kuti ali ndi vutoli, adokotala amalimbikitsa kuti apange zilonda zam'mimba, kuti ziwonetsero zazing'ono zazing'ono zizitha kuchitidwa, makamaka pochitika m'maola 24 mpaka 48 oyamba pakuwonekera kwa zizindikilo zoyambirira. Mvetsetsani momwe biopsy iyenera kuchitidwira.

Zizindikiro zazikulu

Zizindikiro za leukocytoclastic vasculitis zimakhudzana ndikukhazikitsidwa kwa malo achitetezo amthupi m'mitsempha yamagazi, yomwe ndi nyumba zopangidwa ndi ma antibodies, omwe amapangidwa chifukwa chotupa, ndikufalitsa ma antigen. Pambuyo pakupanga malo otetezera chitetezo ndikukhazikika muzombo, zinthu zokhudzana ndi chitetezo cha mthupi zimayambitsidwa, zomwe zimabweretsa kuwonekera kwa zizindikilo, zazikuluzikulu ndizo:

• Kutuluka kwa mawanga ofiira pakhungu;
• Kutentha ndi zotupa;
• Kuyabwa kwambiri;
• Kuwonekera kwa tinatake tozungulira;
• Kutuluka kwa zilonda zotupa.

Zizindikirozi ndizofala kwambiri m'miyendo, ntchafu, matako ndi m'mimba. Kuphatikiza apo, pamavuto akulu kwambiri, zidziwitso zamachitidwe monga kutentha thupi, kuchepa thupi popanda chifukwa, kupweteka kwa minofu, magazi mkodzo kapena ndowe ndikuwonjezera kuchuluka kwa m'mimba, mwachitsanzo. Ndikofunikira panthawiyi kukaonana ndi dokotala kuti adziwe matendawa komanso kufunikira koyambira kuyesedwa.

Onani zizindikiro zina za vasculitis.

Momwe mankhwalawa amachitikira

Nthawi zambiri leukocytoclastic vasculitis, zizindikilo zimazimiririka osafunikira chithandizo chilichonse, komabe ndikofunikira kuti chifukwa chake chimadziwika chifukwa ndizotheka kuti njira zopewera gawo latsopano la vasculitis zikuwonetsedwa, monga kuyimitsidwa kwa mankhwala kapena kuchepa kwa chakudya china, ngati vasculitis imakhudzana ndi chifuwa cha mankhwala osokoneza bongo kapena chakudya, mwachitsanzo.

Nthawi zina, ngati zizindikirazo sizimatha pakapita nthawi kapena zikawoneka, dokotalayo amatha kuwonetsa kugwiritsa ntchito mankhwala ena pofuna kupewa kupititsa patsogolo kwa vasculitis ndikulimbikitsa kusintha kwa munthu, pomwepo kugwiritsa ntchito ma antihistamines kapena corticosteroids, kuphatikiza pakupuma ndikukweza miyendo.