Prurigo Nodularis ndi Khungu Lanu

Zamkati

• Zizindikiro
• Zithunzi
• Chithandizo
• Mankhwala osokoneza bongo
• Majekeseni
• Mankhwala othandiza
• Mankhwala ena
• Mankhwala atsopano
• Malingaliro ena oyang'anira PN yanu
• Thandizo
• Zoyambitsa
• Mfundo zachangu
• Kupewa
• Kutenga

Prurigo nodularis (PN) ndikutuluka khungu kovuta kwambiri. Ziphuphu za PN pakhungu zimatha kukula kuyambira zazing'ono kwambiri mpaka pafupifupi inchi theka mwake. Chiwerengero cha mitundumitundu chimatha kuyambira 2 mpaka 200.

Lingaliro lodziwika ndiloti limachitika chifukwa chakukanda khungu. Khungu loyabwa limatha kukhala chifukwa cha zifukwa zingapo, monga:

• khungu lowuma
• vuto la chithokomiro
• matenda a impso

Kuyabwa kwa PN kumatha kufooketsa kukula kwake. Amaganiziridwa kuti amakhala ndi kuyabwa kwapamwamba kwambiri pakhungu lililonse lakhungu.

Kukanda kumapangitsa kuyabwa kukulirakulira ndipo kumatha kupangitsa kuti ziphuphu zambiri ziwonekere ndikuwonjezera zovuta zomwe zilipo kale.

PN ndizovuta kuchiza. Tiyeni tiwone zizindikiritso ndi njira zothetsera PN.

Zizindikiro

PN imatha kuyamba ngati kachilombo kakang'ono kofiira. Zimapezeka chifukwa chakukanda khungu. Ziphuphu nthawi zambiri zimayambira m'manja kapena m'miyendo yanu koma zimatha kuwonekera m'thupi lanu lonse, kulikonse komwe mungakande.

Mitunduyi imatha kuyabwa kwambiri. Zovuta zitha kukhala:

• zovuta
• crusty ndi mamba
• Amakhala amtundu wautoto wofiirira, wabulauni, kapena wakuda
• nkhanambo
• warty kuyang'ana

Khungu pakati pa mabampu limatha kuuma. Anthu ena omwe ali ndi PN amakumananso ndi kuwotcha, mbola, ndi kutentha kwakung'onong'ono, malinga ndi kuwunika kwa 2019.

Ziphuphu zimatha kukhala ndi matenda achiwiri kuchokera pakukanda pafupipafupi.

Kuyabwa kwambiri kumatha kufooketsa, kulepheretsa kugona mokwanira ndikusokoneza zomwe mumachita tsiku ndi tsiku. Izi zitha kupangitsa kuti anthu omwe ali ndi PN azimva kupsinjika komanso kukhumudwa.

Ziphuphu zimatha kutha ngati munthuyo atasiya kuzikanda. Amatha kusiya zipsera nthawi zina.

Zithunzi

Chithandizo

Cholinga cha chithandizo cha PN ndikuphwanya kuzungulira kwakanthawi pochepetsa kuyabwa.

Wopereka chithandizo chamankhwala adzafunika kuthana ndi vuto lililonse lomwe limakupangitsani kuyabwa komanso kukanda.

Chithandizo chodziwika bwino cha PN chimaphatikizapo mafuta opaka m'mutu komanso mankhwala amtundu uliwonse.

Chifukwa kuyabwa ndikowopsa ndipo vuto lililonse ndi losiyana, mungafunike kuyesa njira zingapo zochiritsira kuti mupeze zomwe zikukuyenderani bwino.

PN ndi matenda omwe sanaphunzitsidwe.

Mwa anthu ena, palibe chifukwa chodziwika cha kuyabwa. Kwa anthuwa, palibe mankhwala amodzi othandiza.

Pakadali pano, US Food and Drug Administration (FDA) sinavomereze njira zilizonse zochizira PN. Komabe, pali mankhwala ambiri omwe akufufuzidwa omwe atha kugwiritsidwa ntchito ngati mankhwala kuti athetse vutoli.

Onetsetsani kuti mukambirane zovuta zomwe zingachitike chifukwa cha mankhwala komanso kugwiritsa ntchito mankhwala omwe mulibe ndi omwe akupatsani chithandizo chamankhwala.

Mankhwala osokoneza bongo

Wothandizira zaumoyo wanu akhoza kupereka mankhwala ena owonjezera pa-counter (OTC) kapena mankhwala azitsamba kuti muchepetse kuyabwa komanso kuziziritsa khungu lanu.

Zitsanzo zingaphatikizepo:

• timadzi topical steroid monga clobetasol kapena calcineurin inhibitors monga pimecrolimus. (Izi zitha kuphimbidwa kuti ziwathandize kugwira bwino ntchito.)
• apakhungu malasha phula
• Mafuta a vitamini D-3 (calcipotriol)
• kirimu wa capsaicin
• alireza

Majekeseni

Wothandizira zaumoyo wanu akhoza kunena za jakisoni wa corticosteroid (Kenalog) wamavuto ena.

Mankhwala othandiza

Wothandizira zaumoyo wanu akhoza kukupatsani mankhwala kapena kupereka mankhwala OTC antihistamines kuti akuthandizeni kugona usiku.

Angakupatseninso mankhwala omwe amagwiritsidwa ntchito ngati mankhwala ochepetsa nkhawa kuti akuthandizeni kusiya kukanda. Paroxetine ndi amitriptyline apambana pothandiza ma PN ma nodule kuti asinthe.

Mankhwala ena

Mankhwala omwe angathandize kuchepetsa mitsempha ndi kuchepetsa kuyabwa ndi awa:

• Cryotherapy. Cryotherapy ndikugwiritsa ntchito kutentha kozizira kwambiri pachilondacho
• Phototherapy. Phototherapy imagwiritsa ntchito kuwala kwa UV (UV).
• Psoralen imagwiritsidwa ntchito limodzi ndi UV. Psoralen ndi UVA ogwiritsidwa ntchito limodzi amadziwika kuti PUVA.
• Laser yopaka utoto. Laser yopaka utoto ndi njira yothandizira kupha maselo omwe ali ndi matenda.
• Chithandizo cha laser cha Excimer. Laser yotulutsa ma nanometer 308 ili ndi PN yomwe sinayankhe mankhwala ena.

Wopereka chithandizo chamankhwala angathenso kukuwuzani kuti musinthe zizolowezi zanu kuti zikuthandizeni kusiya kukanda.

Mankhwala atsopano

Mayesero ena okhudzana ndi kugwiritsa ntchito mankhwala osokoneza bongo asonyeza kuti alonjeza kuchepetsa kuyabwa.

• naloxone intravenous and naltrexone oral mu-opioid receptor antagonists, omwe atha kukhala ndi zoyipa zoyambirira
• immunosuppressants, omwe amaphatikizapo cyclosporine ndi methotrexate
• gabapentinoids, omwe amagwiritsidwa ntchito kwa anthu omwe samayankha mankhwala ena kapena omwe ali ndi ma neuropathies opweteka
• thalidomide, yomwe yawonetsedwa kuti ndiyothandiza, koma imawonedwa ngati njira yomaliza chifukwa cha zovuta zina
• nalbuphine ndi nemolizumab, zomwe tsopano zikuyesedwa
• isoquercetin, yomwe imachokera ku chomera quercetin
• , yomwe ndi mankhwala ojambulidwa

Malingaliro ena oyang'anira PN yanu

Khungu la aliyense ndi losiyana, ndipo zimatenga nthawi kuti mupeze chizolowezi chomwe chimathandiza kuyabwa kwanu.

Kuphatikiza mankhwala kungagwire ntchito bwino. Ndikofunika kuyesa kuswa mkombero woyeserera kuti tipewe maqhubu ambiri ndikulola akalewo kuti athetse.

Kuphatikiza pa mankhwala omwe adakupatsani ndi mafuta a OTC:

• Gwiritsani ntchito phukusi la madzi oundana kuti muziziritsa malo oyipa.
• Sambani mofunda, wamfupi ndi colloidal oatmeal.
• Limbikitsani mafuta pafupipafupi ndi Vaselini kapena kirimu cha hypoallergenic.
• Gwiritsani ntchito sopo wopanda zonunkhira ndi zinthu zina pakhungu loyera.

Thandizo

Lumikizanani ndi Nodular Prurigo International kuti mumve zambiri kapena kuti mulowe nawo pagulu lawokha la Facebook kapena mutsegule gulu la Facebook.

Kuchita nawo mayesero azachipatala a PN ndi njira inanso.

Zoyambitsa

Zomwe zimayambitsa PN sizimamveka bwino, koma zotupa zimakhulupirira kuti ndizotsatira zachikopa, zomwe zimatha kukhala chifukwa cha zifukwa zambiri.

PN yakhala ikugwirizana ndi zochitika zingapo, kuphatikiza:

• dermatitis ya atopic (chikanga)
• matenda ashuga
• aakulu impso kulephera
• matenda otupa chiwindi a C.
• matenda amitsempha
• matenda amisala
• post-herpetic neuralgia
• lymphoma
• ndere
• congestive mtima kulephera
• Matenda osokoneza bongo (COPD)
• HIV
• Mankhwala ena a khansa (pembrolizumab, paclitaxel, ndi carboplatin)

Zimaganiziridwa kuti PN imachitika pomwe zinthu zina zimayambitsa kuyabwa komanso kukanda kosalekeza (kuzungulira koyenda), zomwe zimayambitsa zotupa.

Ngakhale vutoli litathetsedwa, PN akuti nthawi zina imapitilira.

Komanso kafukufuku wa 2019 akuti pafupifupi 13% ya anthu omwe ali ndi PN alibe matenda kapena zifukwa zina.

Ofufuza akuyang'ana njira zomwe zimakhudzidwa ndi PN, monga:

• kusintha kwa maselo akhungu
• ulusi wamitsempha
• ma neuropeptides ndi neuroimmune system amasintha

Chifukwa chomwe chitukuko cha PN chimawonekera bwino, ofufuza akuyembekeza kuti chithandizo chazotheka chikhala chotheka.

Mfundo zachangu

• PN imafala kwambiri pakati pa anthu azaka zapakati pa 20 ndi 60.
• PN imakhudza amuna ndi akazi mofanana.
• PN ndiyosowa. Pali zochepa zofufuza zakukula kwake kapena kuchuluka kwake. Kafukufuku wa 2018 wa odwala 909 omwe ali ndi PN adapeza kuti odwala aku Africa American amayenera kukhala ndi PN kuposa azungu.

Kupewa

Mpaka makina enieni a PN adziwike, ndizovuta kupewa. Kusakanda khungu kungakhale njira yokhayo.

Ngati mwakopeka ndi PN, chifukwa cha majini kapena matenda oyambitsa matenda, yang'anani khungu lanu mosamala. Onani wopereka chithandizo chamankhwala kuti akuthandizeni pakuchepetsa kwanthawi yayitali. Yesetsani kuyimitsa kuzungulira kulikonse kusanayambe.

Zithandizo zambiri zitha kuthandiza kuyabwa zisanakhale zovuta kuzisamalira.

Kutenga

PN ndi khungu loyabwa kwambiri lomwe limatha kulepheretsa. Zomwe zimayambitsa sizimveka bwino, koma zimadziwika kuti zimalumikizidwa ndi zochitika zina zingapo.

Mankhwala ambiri ndi otheka, koma zingatenge kanthawi kuti muthane ndi PN yanu. Zikuwoneka kuti kuphatikiza kwamankhwala apakhungu, mankhwala, ndi njira zina zakuchiritsira kungakuthandizireni.

Nkhani yabwino ndiyakuti mankhwala ndi njira zingapo zatsopano zamankhwala zikupangika ndikuyesedwa. Pomwe ofufuza amaphunzira zambiri za makina a PN, njira zochiritsira zowonjezereka zidzapangidwa.