VIPoma

VIPoma ndi khansa yosawerengeka kwambiri yomwe nthawi zambiri imakula kuchokera m'maselo am'magazi otchedwa islet cell.

VIPoma imapangitsa kuti maselo mumankhwala apange mahomoni ochulukirapo otchedwa vasoactive intestinal peptide (VIP). Hormone iyi imawonjezera kutulutsa kuchokera m'matumbo. Imapumulitsanso minofu yosalala m'mimba.

Zomwe zimayambitsa VIPomas sizikudziwika.

Ma VIPomas nthawi zambiri amapezeka mwa achikulire, makamaka azaka pafupifupi 50. Amayi ndi omwe amakhudzidwa kwambiri kuposa amuna. Khansara iyi ndiyosowa. Chaka chilichonse, pafupifupi munthu m'modzi mwa anthu 10 miliyoni amapezeka ndi VIPoma.

Zizindikiro za VIPoma zitha kuphatikizira izi:

• Kupweteka m'mimba ndi cramping
• Kutsekula m'mimba (madzi, komanso nthawi zambiri)
• Kutaya madzi m'thupi
• Kutuluka kapena kufiira kwa nkhope
• Zilonda zam'mimba chifukwa cha potaziyamu wamagazi ochepa (hypokalemia)
• Nseru
• Kuchepetsa thupi

Wothandizira zaumoyo adzakuyesani ndikufunsani za mbiri yanu yazachipatala.

Mayeso omwe angachitike ndi awa:

• Mayeso am'magazi am'magazi (zoyambira kapena zamagulu zamagetsi)
• CT scan pamimba
• MRI ya pamimba
• Kupondapo chopondapo chifukwa cha kutsekula m'mimba ndi milingo yama electrolyte
• Mulingo wa VIP m'magazi

Cholinga choyamba cha mankhwala ndikuwongolera kusowa kwa madzi m'thupi. Zamadzimadzi zimaperekedwa kudzera mumitsempha (madzi am'mitsempha) kuti alowe m'malo mwa madzi omwe amatayika m'mimba.

Cholinga chotsatira ndikuchepetsa kutsegula m'mimba. Mankhwala angathandize kuchepetsa matenda otsekula m'mimba. Imodzi mwa mankhwalawa ndi octreotide. Ndi mtundu wopangidwa ndi mahomoni achilengedwe omwe amalepheretsa kuchita kwa VIP.

Mpata wabwino kwambiri wochiritsidwa ndi opaleshoni yochotsa chotupacho. Ngati chotupacho sichinafalikire ku ziwalo zina, opaleshoni imatha kuchiritsa vutoli.

Mutha kuchepetsa nkhawa zamankhwala ndikulowa nawo gulu lothandizira khansa. Kugawana ndi ena omwe akumana ndi mavuto omwe akukumana nawo kungakuthandizeni kuti musamve nokha.

Opaleshoni imatha kuchiritsa ma VIPomas. Koma, mu gawo limodzi mwa magawo atatu mpaka theka la anthu, chotupacho chinafalikira pofika nthawi yodziwika ndipo sichingachiritsidwe.

Zovuta zingaphatikizepo:

• Khansa imafalikira (metastasis)
• Mtima kumangidwa kuchokera kutsika kwa potaziyamu wamagazi
• Kutaya madzi m'thupi

Ngati muli ndi kutsekula m'madzi kwa masiku opitilira 2 mpaka 3, itanani omwe akukuthandizani.

Chotupa chotulutsa Vasoactive m'matumbo chotulutsa peptide; Matenda a VIPoma; Pancreatic endocrine chotupa

• Miphalaphala

Tsamba la National Cancer Institute. Pancreatic neuroendocrine tumors (islet cell tumors) chithandizo (PDQ) - mtundu wa akatswiri azaumoyo. www.cancer.gov/types/pancreatic/hp/pnet-kuchiza-pdq. Idasinthidwa pa February 8, 2018. Idapezeka Novembala 12, 2018.

Schneider DF, Mazeh H, Lubner SJ, Jaume JC, Chen H. Khansa ya endocrine system. Mu: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, olemba. Chipatala cha Abeloff's Oncology. 5th ed. Philadelphia, PA: Elsevier Saunders; 2014: chap 71.

Vella A. Mahomoni am'mimba ndi zotupa m'matumbo. Mu: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, olemba. Buku la Williams la Endocrinology. Wolemba 13. Philadelphia, PA: Elsevier; 2016: chap 38.