Cholangiocarcinoma

Cholangiocarcinoma (CCA) ndikukula kosavuta kwa khansa (koyipa) mu imodzi mwanjira zomwe zimanyamula bile kuchokera m'chiwindi kupita m'matumbo ang'onoang'ono.

Zomwe zimayambitsa CCA sizikudziwika. Komabe, ambiri mwa zotupazi amakhala atakula kale panthawi yomwe amapezeka.

CCA imatha kuyamba kulikonse m'mbali mwa ndulu. Zotupa izi zimatseka timitsempha ta ndulu.

Amuna ndi akazi amakhudzidwa. Anthu ambiri ndi achikulire kuposa 65.

Anthu omwe ali ndi mavuto azaumoyo otsatirawa atha kukhala ndi mwayi wopanga CCA:

• Mitsuko yamoto (choledochal) zotupa
• Matenda a biliary ndi kutupa kwa chiwindi
• Mbiri ya matenda opatsirana ndi nyongolotsi, zotupa m'chiwindi
• Pulayimale sclerosing cholangitis
• Zilonda zam'mimba

Zizindikiro za CCA zitha kuphatikizira izi:

• Malungo ndi kuzizira
• Zojambula zadothi ndi mkodzo wakuda
• Kuyabwa
• Kutaya njala
• Ululu m'mimba chakumanja komwe kumatha kuwonekera kumbuyo
• Kuchepetsa thupi
• Chikasu cha khungu (jaundice)

Wothandizira zaumoyo wanu adzakuyesani. Kuyesedwa kudzachitika kuti muone ngati pali chotupa kapena kutsekeka mu chotumphuka cha bile. Izi zingaphatikizepo:

• M'mimba mwa CT scan
• M'mimba ultrasound
• Ndondomeko yomwe imagwiritsa ntchito mawonekedwe owonera kuti ayang'ane ma ducts (ERCP), pomwe minofu imatha kutengedwa ndikuyang'aniridwa ndi microscope

Kuyezetsa magazi komwe kungachitike ndi monga:

• Kuyesa kwa chiwindi (makamaka zamchere phosphatase kapena milingo ya bilirubin)
• Kuwerengera kwathunthu kwa magazi (CBC)

Cholinga ndikuthetsa khansa komanso kutsekeka komwe kumayambitsa. Ngati kuli kotheka, opareshoni yochotsa chotupacho ndiye mankhwala omwe angasankhe ndipo atha kuchiritsidwa. Kawirikawiri khansara imakhala itafalikira kale kwanuko kapena kudera lina la thupi panthawi yomwe imapezeka. Zotsatira zake, opareshoni yochiza khansa siyotheka.

Chemotherapy kapena radiation ingaperekedwe pambuyo pa opaleshoni kuti muchepetse mwayi wobwerera khansa.

Muzochitika zina, kuyesa kwa chiwindi kumatha kuyesedwa.

Thandizo la Endoscopic lokhala ndi ma stent limatha kuchepetsa kwakanthawi kutsekeka kwa ma biliary ducts. Izi zikhozanso kuthana ndi jaundice pomwe chotupacho sichingachotsedwe.

Kuchotsa kwathunthu chotupacho kumapangitsa anthu ena kupulumuka ndi mwayi wokhoza kuchiritsidwa.

Ngati chotupacho sichingachotsedwe kotheratu, nthawi zambiri mankhwala sangathe. Ndi chithandizo, pafupifupi theka la anthu omwe akhudzidwa amakhala chaka chimodzi, ndipo theka limakhala motalikirapo, koma osapitilira zaka zisanu.

Hospice nthawi zambiri imakhala njira yabwino kwa anthu omwe ali ndi CCA omwe sangachiritsidwe.

Mavuto a CCA ndi awa:

• Matenda
• Kulephera kwa chiwindi
• Kufalikira (metastasis) kwa chotupa ku ziwalo zina

Itanani omwe amakupatsani ngati muli ndi matenda a jaundice kapena matenda ena a cholangiocarcinoma.

Khansa yotulutsa khansa

• Dongosolo m'mimba
• Njira yopanda madzi

Tsamba la National Cancer Institute. Chithandizo cha khansa yamagazi (cholangiocarcinoma) (PDQ) - mtundu wa akatswiri azaumoyo. www.cancer.gov/types/liver/hp/bile-duct-kuchiritsa-pdq. Idasinthidwa pa Seputembara 23, 2020. Idapezeka Novembala 9, 2020.

Rajkomar K, Koea JB. Intrahepatic cholangiocarcinoma. Mu: Jarnagin WR, Mkonzi. Opaleshoni ya Blumgart ya Chiwindi, Biliary Tract ndi Pancreas. Lachisanu ndi chimodzi. Philadelphia, PA: Elsevier; 2017: chap 50.

Rizvi SH, Gores GJ. Zotupa zaminyewa ya ndulu, ndulu, ndi ampulla. Mu: Feldman M, Friedman LS, Brandt LJ, olemba. Sleisenger ndi Matenda a Mimba ndi a Fordtran Amatenda a Chiwindi. 11th ed. Philadelphia, PA: Elsevier; 2021: mutu 69.