Glucagonoma

Glucagonoma ndi chotupa chosowa kwambiri cha maselo am'mimba am'mimba, omwe amatsogolera ku mahomoni ochulukirapo m'magazi.

Glucagonoma nthawi zambiri amakhala ndi khansa (yoyipa). Khansara imakonda kufalikira ndikukula.

Khansara iyi imakhudza ma cell a iscancreas. Zotsatira zake, maselo azisumbu amapanga mahomoni ambiri a glucagon.

Choyambitsa sichikudziwika. Zinthu zakuthupi zimathandizira nthawi zina. Mbiri ya banja la matenda a endocrine neoplasia mtundu I (MEN I) ndiwowopsa.

Zizindikiro za glucagonoma zitha kuphatikizira izi:

• Kusagwirizana kwa shuga (thupi limakhala ndi vuto loswa shuga)
• Shuga wamagazi (hyperglycemia)
• Kutsekula m'mimba
• Ludzu lokwanira (chifukwa cha shuga wambiri wamagazi)
• Kukodza pafupipafupi (chifukwa cha shuga wambiri wamagazi)
• Kuchuluka chilakolako
• Mlomo ndi lilime lotupa
• Kukodza usiku (usiku)
• Kutupa pakhungu kumaso, pamimba, matako, kapena mapazi omwe amabwera ndikupita, ndikuyenda mozungulira
• Kuchepetsa thupi

Nthawi zambiri, khansara idafalikira kale pachiwindi ikapezeka.

Wothandizira zaumoyo adzakuyesani ndikufunsani za mbiri yanu yazachipatala.

Mayeso omwe angachitike ndi awa:

• CT scan pamimba
• Mulingo wa glucagon m'magazi
• Mulingo wa shuga m'magazi

Kuchita opaleshoni kuti muchotse chotupacho nthawi zambiri kumalimbikitsa. Chotupacho sichimayankha chemotherapy.

Mutha kuchepetsa nkhawa zamankhwala ndikulowa nawo gulu lothandizira khansa. Kugawana ndi ena omwe akumana ndi mavuto omwe akukumana nawo kungakuthandizeni kuti musamve nokha.

Pafupifupi 60% mwa zotupazi ali ndi khansa. Kawirikawiri khansayi imafalikira mpaka pachiwindi. Pafupifupi 20% ya anthu omwe angachiritsidwe ndi opaleshoni.

Ngati chotupacho chili m'mapapo okha ndipo opaleshoni yochotsa kuti ichitike bwino, anthu amakhala ndi moyo wazaka zisanu 85%.

Khansara imatha kufalikira mpaka pachiwindi. Kuchuluka kwa shuga m'magazi kumatha kubweretsa mavuto ndi metabolism ndi kuwonongeka kwa minofu.

Itanani omwe akukuthandizani mukawona zizindikiro za glucagonoma.

AMUNA I - glucagonoma

• Matenda a Endocrine

Tsamba la National Cancer Institute. Pancreatic neuroendocrine tumors (islet cell tumors) chithandizo (PDQ) - mtundu wa akatswiri azaumoyo. www.cancer.gov/types/pancreatic/hp/pnet-kuchiza-pdq. Idasinthidwa pa February 8, 2018. Idapezeka Novembala 12, 2018.

Schneider DF, Mazeh H, Lubner SJ, Jaume JC, Chen H. Khansa ya endocrine system. Mu: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, olemba. Chipatala cha Abeloff's Oncology. 5th ed. Philadelphia, PA: Elsevier Saunders; 2014: chap 71.

Vella A. Mahomoni am'mimba ndi zotupa m'matumbo. Mu: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, olemba. Buku la Williams la Endocrinology. Wolemba 13. Philadelphia, PA: Elsevier; 2016: chap 38.