Matenda a acidosis

Metabolic acidosis ndimkhalidwe womwe mumakhala asidi wambiri m'madzi amthupi.

Metabolic acidosis imayamba pamene asidi ochulukirapo amapangidwa mthupi. Zitha kuchitika pomwe impso sizingachotse asidi wokwanira mthupi. Pali mitundu ingapo ya metabolic acidosis:

• Ashuga acidosis (omwe amatchedwanso kuti ashuga ketoacidosis ndi DKA) amakula pomwe zinthu zotchedwa ketone bodies (zomwe zimakhala ndi acidic) zimakhazikika nthawi ya matenda ashuga osalamulirika.
• Hyperchloremic acidosis imayamba chifukwa chotaya sodium bicarbonate yochulukirapo m'thupi, yomwe imatha kuchitika ndikutsekula m'mimba kwambiri.
• Impso (uremia, distal renal tubular acidosis kapena proximal renal tubular acidosis).
• Lactic acidosis.
• Poizoni wa aspirin, ethylene glycol (yemwe amapezeka mu antifreeze), kapena methanol.
• Kutaya madzi m'thupi kwambiri.

Lactic acidosis imachokera ku kuchuluka kwa lactic acid. Lactic acid imapangidwa makamaka m'maselo a minofu ndi maselo ofiira amwazi. Amapanga thupi likawononga chakudya kuti ligwiritse ntchito mphamvu mpweya ukakhala wochepa. Itha kuyambitsidwa ndi:

• Khansa
• Mpweya wa carbon monoxide
• Kumwa mowa kwambiri
• Kuchita masewera olimbitsa thupi mwamphamvu kwa nthawi yayitali kwambiri
• Kulephera kwa chiwindi
• Shuga wamagazi ochepa (hypoglycemia)
• Mankhwala, monga salicylates, metformin, anti-retrovirals
• MELAS (matenda osowa kwambiri a mitochondrial omwe amakhudza kupanga mphamvu)
• Kusowa kwa okosijeni kwakanthawi chifukwa chadzidzidzi, kulephera kwa mtima, kapena kuchepa kwa magazi m'thupi
• Kugwidwa

Zizindikiro zambiri zimayambitsidwa ndi matenda kapena vuto lomwe limayambitsa kagayidwe kachakudya acidosis. Kagayidwe kachakudya acidosis yokha nthawi zambiri amachititsa kupuma mofulumira. Kukhala wosokonezeka kapena wotopa kwambiri kumatha kuchitika. Kuchepetsa kagayidwe kachakudya acidosis kumatha kubweretsa mantha kapena imfa. Nthawi zina, kagayidwe kachakudya kwa acidosis kumatha kukhala kofatsa, kosatha (kosatha).

Mayeserowa atha kuthandiza kuzindikira kuti acidosis. Amathanso kudziwa ngati choyambitsa ndi vuto lakupuma kapena vuto la kagayidwe kachakudya. Mayeso atha kuphatikiza:

• Magazi amitsempha yamagazi
• Gawo loyambira la kagayidwe kachakudya, (gulu la mayeso amwazi omwe amayesa kuchuluka kwanu kwa sodium ndi potaziyamu, ntchito ya impso, ndi mankhwala ena ndi ntchito)
• Maketoni amwazi
• Kuyesa kwa Lactic acid
• Mkodzo ketoni
• Mkodzo pH

Mayeso ena angafunike kudziwa chomwe chimayambitsa acidosis.

Chithandizochi chimafunikira vuto laumoyo lomwe limayambitsa acidosis. Nthawi zina, sodium bicarbonate (mankhwala mu soda) angaperekedwe kuti achepetse acidity yamagazi. Nthawi zambiri, mumalandira madzi ambiri kudzera mumitsempha yanu.

Maganizo adzadalira matenda omwe amayambitsa vutoli.

Kuchepetsa kwambiri kagayidwe kachakudya acidosis kumatha kubweretsa mantha kapena imfa.

Funani thandizo lachipatala ngati muli ndi zizindikiro za matenda aliwonse omwe angayambitse kagayidwe kachakudya acidosis.

Matenda a shuga ketoacidosis amatha kupewedwa poyang'anira mtundu wa 1 wa matenda ashuga.

Acidosis - kagayidwe kachakudya

• Kupanga kwa insulin ndi matenda ashuga

(Adasankhidwa) Hamm LL, DuBose TD. Kusokonezeka kwa kuchepa kwa asidi. Mu: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, olemba. Brenner ndi Rector a Impso. 11th ed. Philadelphia, PA: Elsevier; 2020: chap 16.

Palmer BF. Matenda a acidosis. Mu: Feehally J, Floege J, Tonelli M, Johnson RJ, olemba. Chachikulu Chachipatala Nephrology. Lachisanu ndi chimodzi. Philadelphia, PA: Elsevier; 2019: chaputala 12.

Seifter JL. Mavuto amadzimadzi. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 110.