Zamgululi

Zamkati

• Musanatenge baricitinib,
• Baricitinib itha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, itanani dokotala wanu mwachangu:

Baricitinib akuwerengedwa pakadali pano pochiza matenda a coronavirus 2019 (COVID-19) kuphatikiza ndi remdesivir (Veklury). A FDA avomereza Chilolezo Chogwiritsa Ntchito Mwadzidzidzi (EUA) chololeza kugawa baricitinib kuti azichitira achikulire ena ndi ana azaka 2 kapena kupitilira omwe ali mchipatala ndi matenda a COVID-19.

Kutenga baricitinib kungachepetse kuthekera kwanu kothana ndi matenda ndikuwonjezera chiopsezo choti mutenge matenda akulu, kuphatikiza matenda owopsa a fungal, bakiteriya, kapena ma virus omwe amafalikira mthupi lonse. Matendawa angafunike kuthandizidwa kuchipatala ndipo atha kupha. Uzani dokotala wanu ngati nthawi zambiri mumakhala ndi matenda aliwonse kapena ngati mukuganiza kuti mutha kukhala ndi matenda aliwonse pano. Izi zimaphatikizapo matenda ang'onoang'ono (monga mabala otseguka kapena zilonda), matenda omwe amabwera ndikadutsa (monga zilonda zozizira), ndi matenda opatsirana omwe samatha. Uzani dokotala ngati mukumwa mankhwala omwe amachepetsa chitetezo chamthupi monga awa: abatacept (Orencia); adalimumab (Humira); azathioprine (Azasan, Imuran); chitsimikizo cha peolol (Cimzia); cyclosporine (Gengraf, Neoral, Sandimmune); etanercept (Enbrel); golimumab (Simponi); infliximab (Remicade); leflunomide (Arava); methotrexate (Otrexup; Rasuvo, Trexall); rituximab (Rituxan); sarilumab (Kevzara); steroids kuphatikizapo dexamethasone, methylprednisolone (Medrol), prednisolone (Prelone), ndi prednisone (Rayos); tocilizumab (Actemra); ndi tofacitinib (Xeljanz).

Dokotala wanu adzakuyang'anirani ngati muli ndi matendawa mukamalandira chithandizo chake. Ngati muli ndi zizindikiro zotsatirazi musanayambe kumwa mankhwala kapena ngati mukukumana ndi zizindikiro zotsatirazi mukamalandira chithandizo kapena mutangochoka kumene, pitani kuchipatala nthawi yomweyo: malungo; thukuta; kuzizira; kupweteka kwa minofu; chifuwa; kupuma movutikira; kuonda; khungu lofunda, lofiira, kapena lopweteka; zilonda pakhungu; kumverera pafupipafupi, kupweteka, kapena kutentha nthawi yokodza; kutsegula m'mimba, kapena kutopa kwambiri.

Mutha kukhala kuti mwadwala kale chifuwa chachikulu (TB; matenda akulu am'mapapo) koma mulibe zizindikiro zilizonse za matendawa. Poterepa, kutenga baricitinib kungapangitse matenda anu kukhala owopsa ndikupangitsani kukhala ndi zizindikilo. Dokotala wanu adzakuyesani khungu kuti muwone ngati muli ndi kachilombo ka TB musanathe komanso mukamamwa mankhwala a baricitinib. Ngati ndi kotheka, dokotala wanu adzakupatsani mankhwala ochizira matendawa musanayambe kumwa baricitinib. Uzani dokotala ngati mwadwalapo kapena munakhalapo ndi TB, ngati munakhalako kapena munapitako kudziko kumene TB imafala, kapena ngati munakhalapo ndi munthu amene ali ndi TB. Ngati muli ndi zizindikiro zotsatirazi za chifuwa chachikulu cha TB, kapena ngati muli ndi zina mwazizindikiro mukamalandira chithandizo, pitani kuchipatala nthawi yomweyo: kutsokomola, kutsokomola ntchofu zamagazi, kuonda, kuchepa kwa minofu, kapena malungo.

Kutenga baricitinib kungapangitse chiopsezo kuti mukhale ndi lymphoma (khansa yomwe imayamba m'maselo omwe amalimbana ndi matenda) kapena mitundu ina ya khansa. Uzani dokotala wanu ngati mwakhalapo kapena mudakhalapo ndi khansa yamtundu uliwonse.

Baricitinib itha kuwonjezera chiopsezo cha magazi owopsa m'mapapu kapena m'miyendo. Ngati mukumane ndi zotsatirazi, itanani dokotala wanu kapena pitani kuchipatala mwachangu: kupweteka pachifuwa kapena kulemera pachifuwa; kupuma movutikira; chifuwa; kupweteka, kutentha, kufiira, kutupa, kapena kukoma kwa mwendo; kapena kutentha kozizira m'manja, manja, kapena miyendo; kapena kupweteka kwa minofu.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu akhoza kuyitanitsa mayeso ena kuti aone momwe thupi lanu likuyankhira ku baricitinib.

Lankhulani ndi dokotala wanu za chiwopsezo chotenga baricitinib.

Baricitinib imagwiritsidwa ntchito yokha kapena ndi mankhwala ena kuchiza nyamakazi (momwe thupi limagwirira mafupa ake omwe amachititsa kupweteka, kutupa, ndi kutayika kwa ntchito) mwa akulu omwe sanayankhe bwino ku chotupa chimodzi kapena zingapo zotupa necrosis factor (TNF) mankhwala (s). Baricitinib ali mgulu la mankhwala otchedwa Janus kinase (JAK) inhibitors. Zimagwira ntchito pochepetsa magwiridwe antchito amthupi.

Baricitinib imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa popanda chakudya kamodzi patsiku. Tengani baricitinib mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani baricitinib ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Dokotala wanu angafunikire kusiya kwakanthawi kapena kwamuyaya mankhwala mukakumana ndi zovuta zina. Onetsetsani kuti muuze dokotala momwe mukumvera mukamalandira chithandizo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge baricitinib,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la baricitinib, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a baricitinib. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchula mankhwala omwe adatchulidwa mu gawo la CHENJEZO CHENJEZO kapena zotsatirazi: probenecid (Probalan, mu Col-Probenecid). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• Uzani dokotala wanu ngati muli ndi ululu wam'mimba womwe sunapezeke kapena ngati mwakhalapo ndi diverticulitis (kutupa kwa akalowa m'matumbo akulu), kuchepa magazi m'thupi, herpes zoster (ming'alu; zotupa zomwe zingachitike mwa anthu nthomba m'mbuyomu), kapena matenda a chiwindi kapena impso.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Mukakhala ndi pakati mukatenga baricitinib, itanani dokotala wanu.
• Uzani dokotala wanu ngati mukuyamwitsa. Osamayamwa mukamamwa baricitinib.
• uzani dokotala wanu ngati mwalandira kumene kapena mukuyenera kulandira katemera uliwonse. Musakhale ndi katemera uliwonse mukamalandira chithandizo popanda kulankhula ndi dokotala.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Baricitinib itha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, itanani dokotala wanu mwachangu:

• kupweteka m'mimba
• chizolowezi cha matumbo chimasintha

Baricitinib itha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Musanapite kukayezetsa labotale, auzeni adotolo ndi ogwira nawo ntchito kuti mukumwa baricitin.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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