Gout

Gout ndi mtundu wa nyamakazi. Zimachitika pamene uric acid imakhazikika m'magazi ndikupangitsa kutupa m'malo olumikizirana mafupa.

Pachimake gout ndichinthu chowawa chomwe chimakhudza gawo limodzi lokha. Gout yanthawi yayitali ndimagawo obwereza ndikumva kupweteka. Zophatikiza zingapo zimatha kukhudzidwa.

Gout imayamba chifukwa chokhala ndi uric acid wapamwamba kwambiri kuposa thupi lanu. Izi zitha kuchitika ngati:

• Thupi lanu limapanga uric acid wambiri
• Thupi lanu limakhala ndi zovuta kuti lichotse uric acid

Uric acid ikamadzikundikira m'madzimadzi ozungulira malo (synovial fluid), timibulu ta uric acid timapanga. Makina amtunduwu amachititsa kuti olumikizirana achitepo kanthu, ndikupweteka, kutupa ndi kutentha.

Zomwe zimayambitsa sizikudziwika. Gout ikhoza kuthamanga m'mabanja. Vutoli limapezeka kwambiri mwa abambo, azimayi atatha kusamba, komanso anthu omwe amamwa mowa. Anthu akamakula, matenda a gout amafala kwambiri.

Vutoli likhoza kukhalanso mwa anthu omwe ali ndi:

• Matenda a shuga
• Matenda a impso
• Kunenepa kwambiri
• Matenda a kuchepa kwa magazi ndi zina zotere
• Khansa ya m'magazi ndi khansa zina zamagazi

Gout ikhoza kuchitika mutamwa mankhwala omwe amalepheretsa kuchotsa uric acid mthupi. Anthu omwe amamwa mankhwala ena, monga hydrochlorothiazide ndi mapiritsi ena amadzi, amatha kukhala ndi uric acid wambiri m'magazi.

Zizindikiro za pachimake gout:

• Nthawi zambiri, gawo limodzi kapena zingapo zokha zimakhudzidwa. Nthawi zambiri zimakhudza zala zazikulu zakumapazi, mawondo, kapena akakolo. Nthawi zina malo ambiri amatupa ndikumva kuwawa.
• Ululu umayamba mwadzidzidzi, nthawi zambiri usiku. Zowawa nthawi zambiri zimakhala zazikulu, zimafotokozedwa ngati kupweteketsa, kuphwanya, kapena kupweteketsa.
• Ophatikizana amawoneka ofunda komanso ofiira. Nthawi zambiri imakhala yofewa komanso yotupa (zimapweteka kuyika pepala kapena bulangeti pamwamba pake).
• Pakhoza kukhala malungo.
• Kuukira kumatha kutha masiku angapo, koma kumatha kubwerera nthawi ndi nthawi. Zowonjezera zina nthawi zambiri zimatenga nthawi yayitali.

Kupweteka ndi kutupa nthawi zambiri kumatha pambuyo pa kuukira koyamba. Anthu ambiri adzaukiridwanso m'miyezi 6 kapena 12 ikubwerayi.

Anthu ena amatha kudwala matendawa. Izi zimatchedwanso gouty nyamakazi. Vutoli limatha kubweretsa kuwonongeka kwamalumikizidwe ndi kusayenda kwa ziwalozo. Anthu omwe ali ndi gout osatha amakhala ndi ululu wolumikizana komanso zizindikilo zina nthawi zambiri.

Madipoziti a uric acid amatha kupanga zotupa pansi pakhungu mozungulira malo kapena malo ena monga zigongono, nsonga zala, ndi makutu. Chotumphuka chimatchedwa tophus, kuchokera ku Chilatini, kutanthauza mtundu wamwala. Tophi (zotupa zingapo) zimatha kutuluka munthu atakhala ndi gout kwa zaka zambiri. Mapewawa amatha kutulutsa zinthu zopepuka.

Mayeso omwe angachitike ndi awa:

• Kusanthula kwamadzimadzi a Synovial (kumawonetsa timibulu ta uric acid)
• Uric acid - magazi
• Ma x-ray ophatikizana (atha kukhala achilendo)
• Chidziwitso cha Synovial
• Uric acid - mkodzo

Mulingo wa uric acid m'magazi opitilira 7 mg / dL (mamiligalamu pa desilita imodzi) ndi wokwera. Koma, sikuti aliyense amene ali ndi uric acid wambiri ali ndi gout.

Tengani mankhwala a gout mwachangu momwe mungathere ngati mwayambiranso.

Tengani mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAIDs) monga ibuprofen kapena indomethacin zizindikiro zikayamba. Lankhulani ndi wothandizira zaumoyo wanu za mlingo woyenera. Mudzafunika mankhwala amphamvu kwa masiku angapo.

• Mankhwala omwe amatchedwa colchicine amathandiza kuchepetsa kupweteka, kutupa, ndi kutupa.
• Corticosteroids (monga prednisone) amathanso kukhala othandiza kwambiri. Wothandizira anu atha kubaya cholumikizira chotupa ndi steroids kuti muchepetse ululu.
• Mukamagwidwa ndi gout m'malo am'mimba mungagwiritse ntchito mankhwala ojambulidwa otchedwa anakinra (Kineret).
• Ululu nthawi zambiri umatha pakadutsa maola 12 mutayamba chithandizo. Nthawi zambiri, zowawa zonse zimapita mkati mwa maola 48.

Mungafunike kumwa mankhwala a tsiku ndi tsiku monga allopurinol (Zyloprim), febuxostat (Uloric) kapena probenecid (Benemid) kuti muchepetse uric acid mu magazi anu. Kuchepetsa uric acid mpaka ochepera 6 mg / dL kumafunikira kuti muchepetse ma uric acid. Ngati muli ndi tophi yowoneka, uric acid iyenera kukhala yocheperako 5 mg / dL.

Mungafunike mankhwala awa ngati:

• Muli ndimagulu angapo mchaka chomwecho kapena ziwopsezo zanu ndizovuta kwambiri.
• Muli ndi kuwonongeka kwa zimfundo.
• Muli tophi.
• Muli ndi matenda a impso kapena miyala ya impso.

Zakudya ndi kusintha kwa moyo kumatha kuthandiza kupewa kuukira kwa gouty:

• Kuchepetsa mowa, makamaka mowa (vinyo wina atha kukhala othandiza).
• Kuchepetsa thupi.
• Chitani masewera olimbitsa thupi tsiku lililonse.
• Chepetsani kudya kwanu nyama yofiira komanso zakumwa zotsekemera.
• Sankhani zakudya zopatsa thanzi, monga zopangidwa ndi mkaka, ndiwo zamasamba, mtedza, nyemba, zipatso (zosapatsa shuga), ndi mbewu zonse.
• Khofi ndi mavitamini C owonjezera (atha kuthandiza anthu ena).

Kuchiza koyenera kwamankhwala oyipa ndikutsitsa uric acid mpaka ochepera 6 mg / dL kumalola anthu kukhala moyo wabwinobwino. Komabe, matendawa amatha kupita ku gout ngati asidi a uric sakuchiritsidwa mokwanira.

Zovuta zingaphatikizepo:

• Matenda a gouty.
• Miyala ya impso.
• Madipoziti mu impso, zikubweretsa aakulu impso kulephera.

Kuchuluka kwa uric acid m'magazi kumalumikizidwa ndi chiopsezo chowonjezeka cha matenda a impso. Kafukufuku akuchitika kuti apeze ngati kutsitsa uric acid kumachepetsa chiopsezo cha matenda a impso.

Itanani omwe akukuthandizani ngati muli ndi matenda a nyamakazi kapena ngati mwayamba kukhala ndi tophi.

Simungaletse gout, koma mutha kupewa zinthu zomwe zimayambitsa zizindikiro. Kutenga mankhwala kuti muchepetse uric acid kumatha kupewa kupitirira kwa gout. Popita nthawi, madipoziti anu a uric acid adzatha.

Matenda a nyamakazi - pachimake; Gout - pachimake; Hyperuricemia; Gout yopweteka; Tophi; Podagra; Gout - matenda; Matenda aakulu; Gout pachimake; Matenda achilendo a gouty

• Impso miyala ndi lithotripsy - kumaliseche
• Impso miyala - kudzisamalira
• Impso miyala - zomwe mungafunse dokotala wanu
• Njira zowongolera kwamikodzo - zotulutsa

• Uric asidi makhiristo
• Tophi gout m'manja

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Edwards NL. Matenda a Crystal. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. Wolemba 25. Philadelphia, PA: Elsevier Saunders; 2016: chap 273.

FitzGerald JD, Neogi T, Choi HK. (Adasankhidwa) Zolemba: osalola kuti chidwi cha gout chizitsogolere gouty arthropathy. Nyamakazi Rheumatol. 2017; 69 (3): 479-482. PMID: 28002890 www.ncbi.nlm.nih.gov/pubmed/28002890. (Adasankhidwa)

Khanna D, Fitzgerald JD, Khanna PP, ndi ena. Malangizo a 2012 American College of Rheumatology pakuwongolera gout. Gawo 1: njira zothandizirana za nonpharmacologic ndi pharmacologic zothandizira hyperuricemia. Kusamalira Matenda a Nyamakazi (Hoboken). 2012; 64 (10): 1431-1446. (Adasankhidwa) PMID: 23024028 www.ncbi.nlm.nih.gov/pubmed/23024028.

Khanna D, Khanna PP, Fitzgerald JD, ndi al. Malangizo a 2012 American College of Rheumatology pakuwongolera gout. Gawo 2: Therapy and antiinfigueatory prophylaxis of acute gouty arthritis. Kusamalira Matenda a Nyamakazi (Hoboken). 2012; 64 (10): 1447-1461. PMID: 23024029 www.ncbi.nlm.nih.gov/pubmed/23024029.

Onetsani JW, Gardner GC. Kugwiritsa ntchito anakinra m'zipatala zomwe zili ndi nyamakazi yokhudzana ndi kristalo. J Rheumatol. 2019 pii: jrheum. 181018. [Epub patsogolo pa kusindikiza]. PMID: 30647192 www.ncbi.nlm.nih.gov/m/pubmed/30647192.