Matenda a hemolytic-uremic

Kupanga poizoni wonga Shiga E coli Matenda a hemolytic-uremic (STEC-HUS) ndimatenda omwe amapezeka nthawi zambiri ngati matenda am'mimba amatulutsa poizoni.Zinthu izi zimawononga maselo ofiira a magazi ndikupangitsa kuvulala kwa impso.

Matenda a Hemolytic-uremic (HUS) amapezeka nthawi zambiri m'mimba mutatha E coli mabakiteriya (Escherichia coli O157: H7). Komabe, vutoli lalumikizananso ndi matenda ena am'mimba, kuphatikiza shigella ndi salmonella. Iyenso yakhala ikugwirizanitsidwa ndi matenda opatsirana m'mimba.

NDIYE wofala kwambiri mwa ana. Ndicho chomwe chimayambitsa kufooka kwa impso kwa ana. Kuphulika kwakukulu kumalumikizidwa ndi nyama ya hamburger yophika yomwe idadetsedwa nayo E coli.

E coli imafalikira kudzera:

• Lumikizanani kuchokera kwa munthu m'modzi
• Kudya zakudya zosaphika, monga mkaka kapena ng'ombe

STEC-HUS sayenera kusokonezedwa ndi atypical HUS (aHUS) yomwe siyokhudzana ndi matenda. Ndi ofanana ndi matenda ena otchedwa thrombotic thrombocytopenic purpura (TTP).

STEC-HUS nthawi zambiri imayamba ndikusanza ndi kutsegula m'mimba, komwe kumatha kukhala kwamagazi. Pakangotha ​​sabata imodzi, munthuyo akhoza kukhala wofooka komanso wokwiya. Anthu omwe ali ndi vutoli amatha kukodza mocheperapo. Kutulutsa kwamkodzo kumatha kuyima.

Kuwonongeka kwa magazi ofiira kumabweretsa zizindikilo za kuchepa kwa magazi m'thupi.

Zizindikiro zoyambirira:

• Magazi pamalopo
• Kukwiya
• Malungo
• Kukonda
• Kusanza ndi kutsegula m'mimba
• Kufooka

Zizindikiro zamtsogolo:

• Kulalata
• Kuchepetsa chidziwitso
• Kutulutsa mkodzo wotsika
• Palibe zotuluka mkodzo
• Pallor
• Khunyu - kawirikawiri
• Kutupa pakhungu komwe kumawoneka ngati mawanga ofiira ofiira (petechiae)

Wothandizira zaumoyo adzayesa. Izi zitha kuwonetsa:

• Kutupa kwa chiwindi kapena ndulu
• Mchitidwe wamanjenje umasintha

Kuyesa kwa Laborator kukuwonetsa zisonyezo za kuchepa kwa magazi m'thupi komanso kulephera kwamphamvu kwa impso. Mayeso atha kuphatikiza:

• Mayeso okutira magazi (PT ndi PTT)
• Zowonjezera zamagetsi zamagetsi zitha kuwonetsa kuchuluka kwa BUN ndi creatinine
• Kuwerengera kwathunthu kwa magazi (CBC) kumatha kuwonetsa kuchuluka kwama cell oyera ndikuchepetsa kuchuluka kwama cell of red
• Kuwerengera kwa ma Platelet kumachepa
• Kuwunika kumawunikira magazi ndi mapuloteni mumkodzo
• Kuyezetsa magazi mkodzo kumatha kuwonetsa kuchuluka kwa mapuloteni mumkodzo

Mayesero ena:

• Chopondapo chikhalidwe chingakhale chabwino pamtundu wina wa E coli mabakiteriya kapena mabakiteriya ena
• Zojambulajambula
• Impso biopsy (nthawi zambiri)

Chithandizo chitha kukhala:

• Dialysis
• Mankhwala, monga corticosteroids
• Kusamalira madzi ndi ma electrolyte
• Kuikidwa magazi ofiira ndi maselo othandiza magazi kuundana

Izi ndi matenda oopsa kwa ana komanso akulu, ndipo amatha kupha. Ndi chithandizo choyenera, oposa theka la anthu adzachira. Zotsatira zake ndizabwino kwa ana kuposa achikulire.

Zovuta zingaphatikizepo:

• Mavuto otseka magazi
• Kuchepa kwa magazi m'thupi
• Impso kulephera
• Kuthamanga kwa magazi kumabweretsa kugwidwa, kukwiya, ndi mavuto ena amanjenje
• Ma platelet ochepa kwambiri (thrombocytopenia)
• Uremia

Itanani omwe akukuthandizani ngati mutakhala ndi zizindikiro za HUS. Zizindikiro zadzidzidzi ndizo:

• Magazi pansi
• Palibe kukodza
• Kuchepetsa kuchepa (kuzindikira)

Itanani omwe akukuthandizani ngati mwakhala ndi gawo la HUS ndipo kutulutsa kwanu kwamkodzo kumachepa, kapena mumakhala ndi zizindikilo zina zatsopano.

Mutha kupewa chifukwa chodziwika, E coli, Pophika hamburger ndi nyama zina bwino. Muyeneranso kupewa kukhudzana ndi madzi osayera ndikutsatira njira zoyenera zosamba m'manja.

HUS; STEC-HUS; Matenda a hemolytic-uremic

• Njira yamikodzo yamwamuna

Alexander T, Licht C, Smoyer WE, Rosenblum ND. Matenda a impso ndi kumtunda kwamikodzo mwa ana. Mu: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, olemba. Brenner ndi Rector a Impso. 11th ed. Philadelphia, PA: Elsevier; 2020: mutu: 72.

Mele C, Noris M, Remuzzi G. Hemolytic uremic matenda. Mu: Ronco C, Bellomo R, Kellum JA, Ricci Z, olemba. Chisamaliro Chachikulu Nephrology. Wachitatu ed. Philadelphia, PA: Elsevier; 2019: chap 50.

(Adasankhidwa) Schneidewend R, Epperla N, Friedman KD. Thrombotic thrombocytopenic purpura ndi hemolytic uremic syndromes. Mu: Hoffman R, Benz EJ, Silberstein LE, et al, olemba. Hematology: Mfundo Zoyambira ndi Zochita. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2018: mutu 134.