Factor XII (Hageman factor) kuchepa

Kuperewera kwa Factor XII ndi vuto lobadwa nalo lomwe limakhudza protein (factor XII) yokhudzana ndi kuphimba magazi.

Mukamatuluka magazi, zochitika zingapo zimachitika mthupi zomwe zimathandiza kuundana kwamagazi. Izi zimatchedwa coagulation cascade. Zimaphatikizapo mapuloteni apadera otchedwa coagulation kapena clotting factor. Mutha kukhala ndi mwayi wambiri wokhetsa magazi ngati chimodzi kapena zingapo mwazimene zikusowa kapena sizikugwira ntchito moyenera.

Factor XII ndichimodzi mwazinthu zotere. Kuperewera kwa izi sikuyambitsa magazi mwachilendo. Koma, magazi amatenga nthawi yayitali kuposa momwe zimakhalira kuti azungidwe mu chubu choyesera.

Kuperewera kwa Factor XII ndi vuto losabadwa nacho.

Nthawi zambiri palibe zisonyezo.

Kuperewera kwa Factor XII kumapezeka nthawi zambiri kuyesa koyeserera kuchitidwa kuti muwonetsedwe pafupipafupi.

Mayeso atha kuphatikiza:

• Factor XII kuyeza zochitika za factor XII
• Nthawi yapadera ya thromboplastin (PTT) kuti muwone kuti zimatenga nthawi yayitali bwanji kuti magazi aumbike
• Kusakaniza kuphunzira, kuyesa kwapadera kwa PTT kutsimikizira kusowa kwa XII

Chithandizo nthawi zambiri sichofunikira.

Izi zitha kukupatsirani zambiri zakusowa kwa XII:

• National Hemophilia Foundation - www.hemophilia.org/Bleeding-Disorders/Types-of-Bleeding-Disorders/Other-Factor-Deficiencies/Factor-XII
• National Organisation for Rare Disways - rarediseases.org/rare-diseases/factor-xii-deficiency
• NIH Genetic and Rare Diseases Information Center - rarediseases.info.nih.gov/diseases/6558/factor-xii-deficiency

Zotsatira zake zikuyembekezeka kukhala zabwino popanda chithandizo.

Nthawi zambiri palibe zovuta.

Wothandizira zaumoyo nthawi zambiri amapeza izi akamayesa mayeso ena labu.

Ili ndi vuto lobadwa nalo. Palibe njira yodziwika yopewera izi.

Kuperewera kwa F12; Chosowa cha Hageman; Makhalidwe a Hageman; Kulephera kwa HAF

• Kuundana kwamagazi

Gailani D, Wheeler AP, Neff AT. Zofooka zambiri zomwe zimachitika nthawi zambiri. Mu: Hoffman R, Benz EJ, Silberstein LE, et al, olemba. Hematology: Mfundo Zoyambira ndi Zochita. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2018: mutu 137.

Hall JE. Hemostasis ndi magazi coagulation. Mu: Hall JE, mkonzi. Guyton ndi Hall Textbook of Medical Physiology. Wolemba 13. Philadelphia, PA: Elsevier; 2016: chap 37.

Ragni MV. Matenda a hemorrhagic: coagulation factor deficience. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. Wolemba 25. Philadelphia, PA: Elsevier Saunders; 2016: chap 174.