Mankhwala opatsirana pogwiritsa ntchito mankhwala osokoneza bongo

Kuchepetsa magazi m'thupi chifukwa cha mankhwala osokoneza bongo ndimatenda amwazi omwe amapezeka pomwe mankhwala amayambitsa chitetezo cha mthupi kuti chiwononge maselo ake ofiira. Izi zimapangitsa kuti maselo ofiira awonongeke kuposa kale, njira yotchedwa hemolysis.

Kuchepa kwa magazi m'thupi ndimomwe thupi limakhala lilibe maselo ofiira okwanira okwanira. Maselo ofiira ofiira amapereka mpweya kumatenda amthupi.

Nthawi zambiri, maselo ofiira amakhala pafupifupi masiku 120 m'thupi. Mu hemolytic anemia, maselo ofiira m'magazi amawonongeka kale kuposa zachilendo.

Nthawi zina, mankhwala amatha kupangitsa chitetezo cha mthupi kulakwitsa maselo anu ofiira a zinthu zakunja. Thupi limayankha popanga ma antibodies kuti aukire maselo ofiira amthupi omwewo. Ma antibodies amalumikizana ndi maselo ofiira am'magazi ndikuwapangitsa kuti athane msanga.

Mankhwala omwe angayambitse mtundu uwu wa kuchepa kwa magazi m'thupi ndi awa:

• Cephalosporins (gulu la maantibayotiki), chomwe chimayambitsa matendawa
• Dapsone
• Levodopa
• Levofloxacin
• Methyldopa
• Nitrofurantoin
• Mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAIDs)
• Penicillin ndi zotumphukira zake
• Phenazopyridine (pyridium)
• Quinidine

Matenda omwe amapezeka kawirikawiri ndi hemolytic anemia chifukwa chosowa shuga-6 phosphate dehydrogenase (G6PD). Poterepa, kuwonongeka kwamagazi ofiira kumachitika chifukwa cha kupsinjika kwamtundu wina m'selo.

Kuchepa kwa magazi komwe kumayambitsa matenda osokoneza bongo ndikosowa kwa ana.

Zizindikiro zimatha kuphatikizira izi:

• Mkodzo wakuda
• Kutopa
• Mtundu wa khungu wotumbululuka
• Kuthamanga kwa mtima mwachangu
• Kupuma pang'ono
• Khungu lachikaso ndi azungu amaso (jaundice)

Kuyezetsa thupi kumatha kuwonetsa ntchafu zokulitsa. Mutha kukhala ndi mayeso amwazi ndi mkodzo kuti muthandize kuzindikira vutoli.

Mayeso atha kuphatikiza:

• Kuwerengera kwathunthu kwa ma reticulocyte kuti mudziwe ngati maselo ofiira amapangidwa m'mafupa pamlingo woyenera
• Ma Coombs owongoka kapena osawonekera kuti awone ngati pali ma antibodies olimbana ndi maselo ofiira omwe akupangitsa kuti maselo ofiira afe msanga
• Magulu osalunjika a bilirubin kuti ayang'anire jaundice
• Maselo ofiira ofiira
• Seramu haptoglobin kuti muwone ngati maselo ofiira a magazi akuwonongedwa molawirira kwambiri
• Mkodzo hemoglobin kuti muwone ngati hemolysis

Kuyimitsa mankhwala omwe akuyambitsa vutoli kutha kuchepetsa kapena kuwongolera zizindikirazo.

Mungafunike kumwa mankhwala otchedwa prednisone kuti muchepetse chitetezo chamthupi motsutsana ndi maselo ofiira. Kuika magazi mwapadera kungafunike kuti muchepetse zisonyezo zazikulu.

Zotsatira zake ndi zabwino kwa anthu ambiri ngati atasiya kumwa mankhwala omwe akuyambitsa vutoli.

Imfa yoyambitsidwa ndi kuchepa kwa magazi m'thupi ndiyochepa.

Onaninso omwe akukuthandizani ngati muli ndi zizindikilo za matendawa.

Pewani mankhwala omwe adayambitsa vutoli.

Chitetezo cha m'thupi chaching'ono chochepa kwa mankhwala osokoneza bongo; Anemia - immune hemolytic - wachiwiri kwa mankhwala

• Ma antibodies

Michel M. Autoimmune ndi intravascular hemolytic anemias. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. Wolemba 25. Philadelphia, PA: Elsevier Saunders; 2016: chap 160.

Win N, Richards SJ. Anapeza haemolytic anaemias. Mu: Bain BJ, Bates I, Laffan MA, eds. Dacie ndi Lewis Othandiza Hematology. Wolemba 12. Philadelphia, PA: Elsevier; 2017: mutu 13.