Kupita patsogolo kwa supranuclear palsy

Progressive supranuclear palsy (PSP) ndi vuto loyenda lomwe limayamba chifukwa cha kuwonongeka kwa maselo ena amitsempha muubongo.

PSP ndi vuto lomwe limayambitsa zizindikiro zofananira ndi matenda a Parkinson.

Zimakhudza kuwonongeka kwa maselo ambiri aubongo. Madera ambiri amakhudzidwa, kuphatikiza gawo laubongo komwe maselo omwe amayang'anira kuyenda kwa diso amapezeka. Dera laubongo lomwe limayendetsa kukhazikika mukamayenda limakhudzidwanso. Ma lobes akutsogolo aubongo amakhudzidwanso, zomwe zimabweretsa kusintha kwa umunthu.

Zomwe zimayambitsa kuwonongeka kwa ma cell aubongo sizikudziwika. PSP imakula kwambiri pakapita nthawi.

Anthu omwe ali ndi PSP amakhala ndimatumba am'magazi omwe amawoneka ngati omwe amapezeka mwa anthu omwe ali ndi matenda a Alzheimer. Pali kutayika kwa minofu m'malo ambiri amubongo komanso m'malo ena a msana.

Matendawa amawoneka mwa anthu azaka zopitilira 60, ndipo amapezeka kwambiri mwa amuna.

Zizindikiro zimatha kuphatikizira izi:

• Kutaya bwino, kugwa mobwerezabwereza
• Kuyenda patsogolo poyenda, kapena kuyenda mwachangu
• Kugundana ndi zinthu kapena anthu
• Kusintha kwa mawonekedwe akumaso
• Nkhope yolimba kwambiri
• Mavuto amaso ndi masomphenya monga ana osiyana kukula, zovuta kusuntha maso (supranuclear ophthalmoplegia), kusowa mphamvu pakulamulira maso, mavuto otsegula maso
• Zovuta kumeza
• Kugwedezeka, nsagwada kapena nkhope kugwedezeka kapena kupuma
• Dementia wofatsa pang'ono pang'ono
• Umunthu umasintha
• Kusuntha pang'onopang'ono kapena kolimba
• Zovuta pakulankhula, monga kutsika kwa mawu, osatha kunena mawu momveka, mawu osachedwa
• Kuuma ndi kuyenda kolimba m'khosi, pakati pa thupi, mikono, ndi miyendo

Kuyesedwa kwa dongosolo lamanjenje (kuwunika kwamitsempha) kumatha kuwonetsa:

• Dementia yomwe ikuipiraipira
• Kuvuta kuyenda
• Kusuntha kwamaso kocheperako, makamaka mayendedwe okweza ndi otsika
• Masomphenya achilengedwe, kumva, kumva, ndikuwongolera mayendedwe
• Kuyenda kolimba komanso kosagwirizana ngati matenda a Parkinson

Wothandizira zaumoyo atha kuchita izi kuti athetse matenda ena:

• Kujambula kwamaginito (MRI) kumatha kuwonetsa kuchepa kwa ubongo (chizindikiro cha hummingbird)
• Kujambula kwa PET muubongo kumawonetsa kusintha kutsogolo kwa ubongo

Cholinga cha chithandizo ndikuwongolera zizindikilo. Palibe mankhwala odziwika a PSP.

Mankhwala monga levodopa atha kuyesedwa. Mankhwalawa amakweza gawo la mankhwala amubongo otchedwa dopamine. Dopamine amatenga nawo gawo pakuwongolera mayendedwe. Mankhwalawa amatha kuchepetsa zizindikilo zina, monga miyendo yolimba kapena kuyenda pang'onopang'ono kwakanthawi. Koma nthawi zambiri sizothandiza ngati matenda a Parkinson.

Anthu ambiri omwe ali ndi PSP pamapeto pake adzafunika chisamaliro cha nthawi ndi nthawi ndikuwunika momwe amathera muubongo.

Chithandizo nthawi zina chimatha kuchepetsa zizindikilo kwakanthawi, koma matendawo amakula. Kugwiritsa ntchito ubongo kumachepa pakapita nthawi. Imfa imachitika zaka 5 mpaka 7.

Mankhwala atsopano akuphunziridwa kuti athetse vutoli.

Zovuta za PSP ndi monga:

• Kuundana kwamagazi m'mitsempha (deep vein thrombosis) chifukwa chosayenda pang'ono
• Kuvulala kugwa
• Kulephera kuwongolera masomphenya
• Kutaya kwa ubongo kumagwira ntchito pakapita nthawi
• Chibayo chifukwa chovuta kumeza
• Chakudya choperewera (kusowa kwa zakudya m'thupi)
• Zotsatira zoyipa za mankhwala

Itanani omwe akukuthandizani ngati mumagwa nthawi zambiri, ndipo ngati muli ndi khosi lolimba / thupi, komanso mavuto amaso.

Komanso, itanani ngati wokondedwa wanu wapezeka ndi PSP ndipo vutoli lachepa kwambiri kotero kuti simuthanso kusamalira munthuyo kunyumba.

Dementia - nuchal dystonia; Matenda a Richardson-Steele-Olszewski; Khungu - patsogolo supranuclear

• Central dongosolo lamanjenje ndi zotumphukira zamanjenje

Matenda a Jankovic J. Parkinson ndi zovuta zina zoyenda. Mu: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, olemba. Neurology ya Bradley mu Kuchita Zachipatala. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2016: chap 96.

Ling H. Njira zamankhwala zothetsera kuphulika kwapamwamba kwa nyukiliya. J Mov Kusokonezeka. 2016; 9 (1): 3-13. PMID: 26828211 pubmed.ncbi.nlm.nih.gov/26828211/.

Tsamba la National Institute of Neurological Disorder. Pepala lachitetezo cha supranuclear palsy. www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Progressive-Supranuclear-Palsy-Fact-Sheet. Idasinthidwa pa Marichi 17, 2020. Idapezeka pa Ogasiti 19, 2020.