Biliary atresia

Biliary atresia ndikutseka kwamachubu (ma ducts) omwe amanyamula madzi otchedwa bile kuchokera pachiwindi kupita ku ndulu.

Biliary atresia imachitika m'mimbamo ya bile mkati kapena kunja kwa chiwindi ili yopapatiza, yotsekedwa, kapena kulibe. Mitsempha ya ndulu imanyamula madzi am'mimba kuchokera pachiwindi kupita m'matumbo ang'onoang'ono kuwononga mafuta ndi kusefa zinyalala m'thupi.

Zomwe zimayambitsa matendawa sizikudziwika bwinobwino. Zitha kukhala chifukwa cha:

• Matenda a kachilombo pambuyo pobadwa
• Kuwonetseredwa ndi mankhwala owopsa
• Zinthu zingapo zamtundu
• Kuvulala kwa Perinatal
• Mankhwala ena monga carbamazepine

Zimakhudza kwambiri anthu ochokera kum'mawa kwa Asia ndi Africa ndi America.

Miphika ya ndulu imathandizira kuchotsa zinyalala m'chiwindi komanso kunyamula mchere womwe umathandiza kuti m'matumbo pang'ono muwononge mafuta.

Kwa ana omwe ali ndi biliary atresia, kutuluka kwa ndulu kuchokera pachiwindi kupita ku ndulu kumatsekedwa. Izi zitha kubweretsa kuwonongeka kwa chiwindi komanso chiwindi cha chiwindi, chomwe chimatha kupha.

Zizindikiro nthawi zambiri zimayamba kuchitika pakati pa milungu iwiri mpaka 8. Jaundice (mtundu wachikaso pakhungu ndi ntchofu) umayamba pang'onopang'ono pakadutsa milungu iwiri kapena itatu atabadwa. Khanda limatha kunenepa bwino mwezi woyamba. Pambuyo pake, mwanayo amachepa thupi ndikukhala wokwiya, ndipo amakhala ndi jaundice yoyipa.

Zizindikiro zina zitha kuphatikiza:

• Mkodzo wakuda
• Mimba yotupa
• Manyowa onunkha komanso oyandama
• Zojambula zofiirira kapena zadongo
• Kukula pang'onopang'ono

Wothandizira zaumoyo wanu atenga mbiri ya zamankhwala ya mwana wanu ndikuyesa thupi kuti muwone ngati chiwindi chake chikukulitsidwa.

Kuyesera kuti mupeze biliary atresia ndi awa:

• X-ray yam'mimba kuti muwone ngati chiwindi ndi nthenda zakulitsa
• Mimba ya ultrasound kuti muwone ziwalo zamkati
• Kuyezetsa magazi kuti muwone kuchuluka kwa bilirubin
• Hepatobiliary scintigraphy kapena HIDA scan kuti muwone ngati ma ducts a ndulu ndi ndulu zikugwira ntchito bwino
• Chiwindi chimayang'ana kuopsa kwa matenda enaake kapena kuthana ndi zifukwa zina za jaundice
• X-ray ya ma ducts (cholangiogram) kuti muwone ngati ma ducts atsegulidwa kapena atsekedwa

Opaleshoni yotchedwa njira ya Kasai yachitika kulumikiza chiwindi ndi matumbo ang'onoang'ono. Ma ducts achilendo adadutsa. Kuchita opaleshoniyo kumachita bwino kwambiri ngati mwana asanachitike masabata asanu ndi atatu.

Kuika chiwindi kungafunikirebe asanakwanitse zaka 20 nthawi zambiri.

Kuchita opaleshoni yoyambirira kumathandizira kuti mwana wopitilira gawo limodzi mwa atatu azikhala ndi vutoli. Phindu lokhalitsa lakuyika chiwindi silikudziwika, koma likuyembekezeka kukonza kupulumuka.

Zovuta zingaphatikizepo:

• Matenda
• Cirrhosis yosasinthika
• Kulephera kwa chiwindi
• Zovuta pakuchita opaleshoni, kuphatikizapo kulephera kwa njira ya Kasai

Itanani omwe akukuthandizani ngati mwana wanu akuwoneka kuti ali ndi jaundiced, kapena ngati zizindikiro zina za biliary atresia zikuyamba.

Jaundice akhanda - biliary atresia; Wakhanda jaundice - biliary atresia; Extrahepatic ductopenia; Kupita patsogolo koperewera kwa cholangiopathy

• Mwana wakhanda jaundice - kumaliseche
• Matenda a jaundice obadwa kumene - zomwe mungafunse dokotala wanu

• Mayi amapangidwa m'chiwindi

Berlin SC. Kuzindikira kuzindikiritsa kwachinyamata. Mu: Martin RJ, Fanaroff AA, Walsh MC, olemba., Eds. Fanaroff ndi Martin's Neonatal-Perinatal Medicine. 11th ed. Philadelphia, PA: Elsevier; 2020: chap 38.

Cazares J, Ure B, Yamataka A. Biliary atresia. Mu: Holcomb GW, Murphy JP, St. Peter SD, olemba. Opaleshoni ya Ana ya Holcomb ndi Ashcraft. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2020: chap 43.

Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC. Cholestasis. Mu: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, olemba. Nelson Textbook of Pediatrics. Wolemba 21. Philadelphia, PA: Elsevier; 2020: chap 383.

O'Hara SM. Matenda a chiwindi ndi ndulu. Mu: Rumack CM, Levine D, eds. Kuzindikira Ultrasound. 5th ed. Philadelphia, PA: Elsevier; 2018: chap 51.