Urticaria pigmentosa

Urticaria pigmentosa ndi matenda akhungu omwe amatulutsa zigamba za khungu lakuda komanso kuyabwa koyipa. Ming'oma imatha kupezeka pakhungu limeneli.

Urticaria pigmentosa imachitika pakakhala ma cell ambiri otupa (mast cell) pakhungu. Maselo akulu ndi maselo amthupi omwe amathandiza thupi kulimbana ndi matenda. Maselo akulu amatulutsa ndi kutulutsa histamine, yomwe imapangitsa kuti minofu yapafupi itupe ndikutupa.

Zinthu zomwe zingayambitse kutulutsa kwa histamine ndi zizindikilo za khungu zimaphatikizapo:

• Kusisita khungu
• Matenda
• Chitani masewera olimbitsa thupi
• Kumwa zakumwa zotentha, kudya zakudya zokometsera
• Dzuwa, kukhudzana ndi kuzizira
• Mankhwala, monga aspirin kapena ma NSAID ena, codeine, morphine, utoto wa x-ray, mankhwala ena oletsa dzanzi, mowa

Urticaria pigmentosa amapezeka kwambiri mwa ana. Ikhozanso kupezeka kwa akuluakulu.

Chizindikiro chachikulu ndi zigamba za bulauni pakhungu. Zigawozi zimakhala ndi maselo otchedwa mastocyte. Mastocyte akatulutsa mankhwala a histamine, zigamba zimasanduka mabampu ngati ming'oma. Ana aang'ono amatha kukhala ndi chotupa chomwe chimadzazidwa ndi madzi ngati chotupa chikakanda.

Nkhope imathanso kufiira mwachangu.

Zikakhala zovuta, izi zimatha kuchitika:

• Kutsekula m'mimba
• Kukomoka (zachilendo)
• Mutu
• Sungani
• Kugunda kwamtima mwachangu

Wothandizira zaumoyo awunika khungu. Wothandizira akhoza kukayikira urticarial pigmentosa pamene zigamba za khungu zikupukutidwa ndikukweza ziphuphu (ming'oma) ikukula. Izi zimatchedwa chizindikiro cha Darier.

Kuyesa kuti muwone ngati ili ndi:

• Khungu lachikopa kuti lifufuze nambala yochulukirapo yama cell
• Mkodzo histamine
• Kuyesedwa kwa magazi pama cell a magazi ndi kuchuluka kwa tryptase yamagazi (tryptase ndi enzyme yomwe imapezeka m'maselo akuluakulu)

Mankhwala a antihistamine amatha kuthandiza kuthetsa zizindikilo monga kuyabwa ndi kutsuka. Lankhulani ndi omwe amakupatsirani mtundu wa antihistamine yoti mugwiritse ntchito. Corticosteroids yogwiritsidwa ntchito pakhungu ndi mankhwala opepuka amatha kugwiritsidwanso ntchito nthawi zina.

Omwe amakupatsirani mankhwala amatha kupereka mitundu ina ya mankhwala kuti athetse vuto la urticaria pigmentosa.

Urticaria pigmentosa imatha msinkhu pafupifupi theka la ana okhudzidwa. Zizindikiro nthawi zambiri zimakhala bwino mwa ena akamakula.

Kwa akulu, urticaria pigmentosa imatha kubweretsa masocytosis amachitidwe. Ichi ndi vuto lalikulu lomwe lingakhudze mafupa, ubongo, mitsempha, ndi dongosolo lakugaya chakudya.

Mavuto akulu ndi kusasangalala ndi kuyabwa komanso kuda nkhawa ndi mawonekedwe a mawanga. Mavuto ena monga kutsegula m'mimba ndi kukomoka ndi osowa.

Tizilombo tating'onoting'ono titha kuchititsanso vuto kwa anthu omwe ali ndi urticaria pigmentosa. Funsani omwe akukuthandizani ngati mungakhale ndi chida cha epinephrine chomwe mungagwiritse ntchito mukalandira njuchi.

Itanani omwe akukuthandizani mukawona zizindikiro za urticaria pigmentosa.

Chifuwa; Mastocytoma

• Urticaria pigmentosa m'khwapa
• Mastocytosis - imafalikira podula
• Urticaria pigmentosa pachifuwa
• Urticaria pigmentosa - kutseka

Chapman MS. Urticaria. Mu: Habif TP, Dinulos JGH, Chapman MS, Zug KA, olemba. Matenda a Khungu: Kuzindikira ndi Chithandizo. Wolemba 4. Philadelphia, PA: Elsevier; 2018: mutu 3.

Chen D, George TI. Matendawa. Mu: Hsi ED, mkonzi. Hematopathology. Wachitatu ed. Philadelphia, PA: Elsevier; 2018: mutu 20.

Paige DG, Wakelin SH. Matenda a khungu. Mu: Kumar P, Clark M, eds. Kumar ndi Clarke's Clinical Medicine. 9th ed. Philadelphia, PA: Elsevier; 2017: mutu 31.