Chotupa cha Wilms

Chotupa cha Wilms (WT) ndi mtundu wa khansa ya impso yomwe imapezeka mwa ana.

WT ndiye mtundu wodziwika bwino wa khansa ya impso yaubwana. Zomwe zimayambitsa chotupacho mwa ana ambiri sizikudziwika.

Iris wosowa wa diso (aniridia) ndi vuto lobadwa nalo lomwe nthawi zina limalumikizidwa ndi WT. Zowonongeka zina zobadwa zogwirizana ndi khansa ya impso imeneyi zimaphatikizapo mavuto ena amkodzo ndi kutupa kwa mbali imodzi ya thupi, matenda otchedwa hemihypertrophy.

Ndizofala kwambiri pakati pa abale ndi ana amapasa, zomwe zimafotokoza zomwe zingayambitse chibadwa.

Matendawa amapezeka kwambiri kwa ana pafupifupi zaka zitatu. Oposa 90% amapezeka asanakwanitse zaka 10. Nthawi zambiri, zimawoneka mwa ana okalamba kuposa zaka 15, komanso akuluakulu.

Zizindikiro zimatha kuphatikizira izi:

• Kupweteka m'mimba
• Mtundu wosadziwika wa mkodzo
• Kudzimbidwa
• Malungo
• Zovuta zambiri kapena zovuta (malaise)
• Kuthamanga kwa magazi
• Kukula kokulira mbali imodzi yokha ya thupi
• Kutaya njala
• Nseru ndi kusanza
• Kutupa m'mimba (m'mimba hernia kapena misa)
• Kutuluka thukuta (usiku)
• Magazi mumkodzo (hematuria)

Wothandizira zaumoyo adzayesa thupi ndikufunsa mafunso okhudza zizindikiritso za mwana wanu komanso mbiri yazachipatala. Mudzafunsidwa ngati muli ndi mbiri ya khansa m'banja.

Kuyezetsa thupi kumatha kuwonetsa m'mimba. Kuthamanga kwa magazi kumathanso kupezeka.

Mayeso ndi awa:

• M'mimba ultrasound
• X-ray m'mimba
• BUNI
• X-ray pachifuwa kapena CT scan
• Kuwerengera kwathunthu kwa magazi (CBC), kumatha kuwonetsa kuchepa kwa magazi
• Zachilengedwe
• Chilolezo cha Creatinine
• CT scan pamimba mosiyana
• MRI
• Pyelogram yolowera
• MR angiography (MRA)
• Kupenda kwamadzi
• Zamchere mankwala
• Calcium
• Transaminases (michere ya chiwindi)

Mayesero ena amafunika kudziwa ngati chotupacho chafalikira ndi monga:

• Zojambulajambula
• Kusanthula mapapu
• Kujambula PET
• Chisokonezo

Ngati mwana wanu amapezeka kuti ali ndi WT, musamuyendetse kapena kukankhira m'mimba mwa mwanayo. Gwiritsani ntchito chisamaliro mukamasamba ndi kusamalira kuti mupewe kuvulaza chotupa.

Gawo loyamba la chithandizo ndikukhazikitsa chotupacho. Kuyika masitepe kumathandiza wothandizirayo kudziwa momwe khansara yafalikira komanso kukonzekera chithandizo chamankhwala chabwino. Opaleshoni yochotsa chotupacho idakonzedwa posachedwa. Ziphuphu ndi ziwalo zozungulira zimafunikanso kuchotsedwa ngati chotupacho chafalikira.

Mankhwala a radiation ndi chemotherapy nthawi zambiri amayamba pambuyo pa opaleshoni, kutengera gawo la chotupacho.

Chemotherapy yoperekedwa asanachite opereshoni imathandizanso kupewa zovuta.

Ana omwe chotupa chawo sichinafalikire amakhala ndi kuchiritsa kwa 90% ndi chithandizo choyenera. Kulosera kumathandizanso kwa ana ochepera zaka 2.

Chotupacho chimatha kukula kwambiri, koma nthawi zambiri chimakhala chodzitsekera. Kufalikira kwa chotupacho m'mapapu, ma lymph node, chiwindi, fupa, kapena ubongo ndizovuta kwambiri.

Kuthamanga kwa magazi ndi kuwonongeka kwa impso kumatha kuchitika chifukwa cha chotupacho kapena chithandizo chake.

Kuchotsa WT mu impso zonse kungakhudze kugwira kwa impso.

Zovuta zina zomwe zingachitike pakuthandizira kwakanthawi kwa WT zitha kuphatikizira izi:

• Mtima kulephera
• Khansa yachiwiri kwinakwake m'thupi yomwe imayamba pambuyo pochiza khansa yoyamba
• Kutalika kwakanthawi

Itanani yemwe amakupatsani mwana ngati:

• Mumapeza chotupa m'mimba mwa mwana wanu, magazi mkodzo, kapena zizindikiro zina za WT.
• Mwana wanu akuchiritsidwa matendawa ndipo zizindikilo zimakulirakulira kapena zizindikilo zatsopano zimayamba, makamaka kutsokomola, kupweteka pachifuwa, kuwonda, kapena kutentha thupi kosalekeza.

Kwa ana omwe ali pachiwopsezo chachikulu cha WT, kuwunika pogwiritsa ntchito impso za ultrasound kapena kusanthula kwa majini asanabadwe kungatchulidwe.

Nephroblastoma; Chotupa cha impso - Wilms

• Matenda a impso
• Chotupa cha Wilms

Tsamba la National Cancer Institute. Chotupa cha Wilms ndi chithandizo china cha zotupa za impso zaubwana (PDQ) - mtundu wa akatswiri azaumoyo. www.cancer.gov/types/kidney/hp/wilms-treatment-pdq. Idasinthidwa pa June 8, 2020. Idapezeka pa Ogasiti 5, 2020.

Ritchey ML, Mtengo NG, Shamberger RC. Matenda a m'mimba oncology: aimpso ndi adrenal. Mu: Partin AW, Dmochowski RR, Kavoussi LR, Peters CA, olemba. Campbell-Walsh-Wein Urology. Wolemba 12. Philadelphia, PA: Elsevier; 2021: mutu 53.

Pezani nkhaniyi pa intaneti Weiss RH, Jaimes EA, Hu SL. Khansa ya impso. Mu: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, olemba. Brenner ndi Rector a Impso. 11th ed. Philadelphia, PA: Elsevier; 2020: mutu 41.