Autosomal yochulukirapo

Autosomal recessive ndi imodzi mwanjira zingapo zomwe mikhalidwe, matenda, kapena matenda amatha kupatsira kudzera m'mabanja.

Matenda osokoneza bongo amatanthauza kuti pakhale mitundu iwiri ya jini yachilendo kuti matendawa akhalepo.

Kulowa matenda, chikhalidwe, kapena chikhalidwe chimadalira mtundu wa chromosome yomwe imakhudzidwa. Mitundu iwiriyi ndi ma chromosomes autosomal ndi ma chromosomes ogonana. Zimadaliranso kuti khalidweli ndilopambana kapena lowonjezera.

Kusintha kwa jini pa imodzi mwamankhwala 22 oyamba amtundu wa nonsex kumatha kubweretsa vuto la autosomal.

Chibadwa chimabwera awiriawiri. Jini imodzi m'magulu awiriwa imachokera kwa mayi, ndipo jini linalo limachokera kwa abambo. Cholowa chambiri chimatanthauza kuti majini onse awiriwa ayenera kukhala achilendo kuyambitsa matenda. Anthu omwe ali ndi jini imodzi yokha yolakwika mwa awiriwa amatchedwa onyamula.Anthu awa nthawi zambiri samakhudzidwa ndi vutoli. Komabe, amatha kupatsira ana awo chibadwa chachilendo.

Mipata YA KULANDIRA CHIKHALIDWE

Ngati munabadwa kwa makolo omwe onse ali ndi jini yofanana ya autosomal, muli ndi mwayi umodzi mwa anayi wolandira geni yachilendo kuchokera kwa makolo onse ndikupeza matendawa. Muli ndi mwayi wa 50% (1 mu 2) wolandila jini imodzi yachilendo. Izi zingakupangitseni kukhala wonyamula.

Mwanjira ina, kwa mwana wobadwa kwa banja lomwe onse amakhala ndi jini (koma alibe zizindikilo za matenda), zomwe zimayembekezereka pamimba iliyonse ndi izi:

• Mwayi 25% kuti mwana abadwe ali ndi majini awiri abwinobwino (abwinobwino)
• Mwayi 50% kuti mwanayo abadwe ali ndi chibadwa chimodzi chachilendo (chonyamulira, chopanda matenda)
• Mwayi 25% kuti mwana abadwe ali ndi majini awiri achilendo (pachiwopsezo cha matendawa)

Chidziwitso: Zotsatira izi sizikutanthauza kuti anawo azikhala onyamula kapena kukhudzidwa kwambiri.

Chibadwa - autosomal recessive; Cholowa - autosomal recessive

• Autosomal yochulukirapo
• Zolumikizana ndi X zomwe zimalumikizidwa kwambiri
• Chibadwa

Feero WG, Zazove P, Chen F. Zazachipatala zamankhwala. Mu: Rakel RE, Rakel DP, olemba. Buku Lophunzitsira La Banja. 9th ed. Philadelphia, PA: Elsevier Saunders; 2016: chap 43.

Gregg AR, Kuller JA. Chibadwa cha anthu ndi mitundu ya cholowa. Mu: Resnik R, Lockwood CJ, Moore TR, Greene MF, Copel JA, Silver RM, olemba. Creasy ndi Resnik's Maternal-Fetal Medicine: Mfundo ndi Kuchita. 8th ed. Philadelphia, PA: Elsevier; 2019: chap 1.

Korf BR. Mfundo za chibadwa. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 35.