Mayeso a mkodzo 5-HIAA

5-HIAA ndiyeso lamkodzo lomwe limayeza kuchuluka kwa 5-hydroxyindoleacetic acid (5-HIAA). 5-HIAA ndi chinthu chowonongeka cha mahomoni otchedwa serotonin.

Kuyesaku kukuwonetsa kuchuluka kwa 5-HIAA thupi lomwe limapanga. Imeneyi ndi njira yodziwira kuchuluka kwa serotonin mthupi.

Muyenera kuyesa mkodzo wa maola 24. Muyenera kusonkhanitsa mkodzo wanu kwa maola 24 mu chidebe choperekedwa ndi labotale. Wothandizira zaumoyo wanu adzakuuzani momwe mungachitire izi. Tsatirani malangizo ndendende.

Wothandizira anu adzakulangizani, ngati kuli kofunikira, kuti musiye kumwa mankhwala omwe angasokoneze mayeso.

Mankhwala omwe amatha kuwonjezera miyezo ya 5-HIAA akuphatikizapo acetaminophen (Tylenol), acetanilide, phenacetin, glyceryl guaiacolate (yomwe imapezeka m'misempha yambiri ya chifuwa), methocarbamol, ndi reserpine.

Mankhwala omwe angachepetse kuchuluka kwa 5-HIAA ndi heparin, isoniazid, levodopa, monoamine oxidase inhibitors, methenamine, methyldopa, phenothiazines, ndi tricyclic antidepressants.

Mudzauzidwa kuti musadye zakudya zina masiku atatu mayeso asanayesedwe. Zakudya zomwe zingasokoneze muyeso wa 5-HIAA zimaphatikizapo maula, mananazi, nthochi, biringanya, tomato, mapeyala, ndi walnuts.

Chiyesocho chimakodza kukodza kokha, ndipo palibe zovuta.

Mayesowa amayesa mulingo wa 5-HIAA mumkodzo. Nthawi zambiri amachitidwa kuti azindikire zotupa zina m'matumbo (zotupa za carcinoid) ndikutsata momwe munthu alili.

Kuyezetsa mkodzo kungagwiritsidwenso ntchito kupeza matenda omwe amatchedwa systemic mastocytosis ndi zotupa zina za mahomoni.

Mtundu wabwinobwino ndi 2 mpaka 9 mg / 24h (10.4 mpaka 46.8 µmol / 24h).

Mitengo yamtengo wapatali imatha kusiyanasiyana pakati pa ma labotore osiyanasiyana. Ma lab ena amagwiritsa ntchito miyeso yosiyanasiyana kapena amayesa mitundu yosiyanasiyana. Lankhulani ndi omwe akukuthandizani za tanthauzo la zotsatira zanu zoyeserera.

Zotsatira zachilendo zitha kukhala chifukwa cha:

• Zotupa za dongosolo la endocrine kapena zotupa za khansa
• Kuwonjezeka kwama cell amthupi otchedwa mast cell mu ziwalo zingapo (systemic mastocytosis)

Palibe zowopsa pamayesowa.

HIAA; 5-hydroxyindole acetic acid; Serotonin metabolite

Chernecky CC, Berger BJ. H. Mu: Chernecky CC, Berger BJ, olemba. Kuyesa Kwantchito ndi Njira Zakuzindikira. Lachisanu ndi chimodzi. Philadelphia, PA: Elsevier Saunders; 2013: 660-661.

Wolin EM, Jensen RT. Zotupa za Neuroendocrine. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 219.