Mlembi: William Ramirez
Tsiku La Chilengedwe: 23 Sepitembala 2021
Sinthani Tsiku: 13 Novembala 2024
Anonim
Fenofibrate - Mechanism, side effects, interactions and contraindications
Kanema: Fenofibrate - Mechanism, side effects, interactions and contraindications

Zamkati

Fenofibrate amagwiritsidwa ntchito ndi mafuta ochepa, masewera olimbitsa thupi, ndipo nthawi zina ndi mankhwala ena kuti achepetse kuchuluka kwa zinthu zamafuta monga cholesterol ndi triglycerides m'magazi ndikuwonjezera kuchuluka kwa HDL (high-density lipoprotein; mtundu wamafuta zomwe zimachepetsa chiopsezo cha matenda amtima) m'magazi. Kukhazikika kwa cholesterol ndi mafuta m'mbali mwa mitsempha (njira yotchedwa atherosclerosis) kumachepetsa kuthamanga kwa magazi ndipo, chifukwa chake, mpweya umapereka kumtima, ubongo, ndi ziwalo zina za thupi. Izi zimawonjezera chiopsezo cha matenda amtima, angina (kupweteka pachifuwa), sitiroko, ndi matenda amtima. Ngakhale fenofibrate imachepetsa kuchuluka kwamafuta m'magazi, sikunawonetsedwe kuti kumachepetsa chiopsezo cha matenda amtima kapena zikwapu. Fenofibrate ali mgulu la mankhwala otchedwa antilipemic agents. Imagwira ndikufulumizitsa njira zachilengedwe zomwe zimachotsa cholesterol mthupi.

Fenofibrate imabwera ngati kapisozi, kapisozi wochedwa (wotenga nthawi yayitali), komanso piritsi lomwe lingatenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku. Zinthu zina za fenofibrate (Fenoglide, Lipofen, ndi Lofibra) ziyenera kutengedwa ndi chakudya. Mitundu ina (Antara, Fibricor, Tricor, Triglide, ndi Trilipix) itha kutengedwa ndi wopanda chakudya. Funsani dokotala wanu kapena wamankhwala ngati simukudziwa ngati muyenera kumwa mankhwala anu ndi chakudya. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani fenofibrate ndendende monga mwalamulo. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.


Dokotala wanu mwina angakuyambitseni kuchuluka kwa fenofibrate ndipo akhoza kukulitsa kapena kuchepa mlingo wanu kutengera zotsatira za mayeso a labotale omwe mungatenge kuti muyese kuchuluka kwamafuta m'magazi anu. Dokotala wanu angakuuzeni kuti musiye kumwa fenofibrate ngati zotsatira zanu sizikuwonetsa kusintha pakatha miyezi iwiri.

Kumeza mapiritsi otulutsidwa mochedwa; osagawana, kutafuna, kapena kuwaphwanya.

Ngati mukumwa mapiritsi a Triglide, musagwiritse ntchito mapiritsi aliwonse odulidwa kapena osweka.

Fenofibrate imathandizira kuchepetsa kuchuluka kwamafuta m'magazi anu pokhapokha mutapitiliza kumwa. Pitirizani kumwa fenofibrate ngakhale mukumva bwino. Osasiya kumwa fenofibrate osalankhula ndi dokotala.

Mankhwalawa amatha kupatsidwa ntchito zina. Funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge fenofibrate,

  • uzani dokotala ndi wamankhwala ngati mukugwirizana ndi mankhwala aliwonse a fenofibrate, mankhwala aliwonse, kapena chilichonse mwazomwe mukugwiritsa ntchito pa fenofibrate zomwe mumamwa. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
  • Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala omwe simukulembera, mavitamini, zowonjezera zakudya, kapena mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: maanticoagulants ('ochepetsa magazi') monga warfarin (Coumadin); colchicine (Colcrys, mu Col-Probenecid); okodzetsa ('mapiritsi amadzi'); zotchinga beta monga atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), ndi propranolol (Inderal); HMG-CoA reductase inhibitors (cholesterol-yotsitsa othandizira) monga atorvastatin (Lipitor), lovastatin (Mevacor), pravastatin (Pravachol), rosuvastatin (Crestor), ndi simvastatin (Zocor); mankhwala othandizira mahomoni; njira zolerera za mahomoni (mapiritsi olera, zigamba, zopangira, mphete, ndi jakisoni); ndi ma immunosuppressants monga cyclosporine (Sandimmune, Neoral) ndi tacrolimus (Prograf). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
  • ngati mukumwa utomoni wa bile acid monga cholestyramine (Questran), colesevelam (WelChol), kapena colestipol (Colestid), tengani ola limodzi pambuyo kapena maola 4-6 musanatenge fenofibrate.
  • uzani dokotala wanu ngati mwakhalapo ndi matenda a impso, chiwindi, kapena ndulu. Dokotala wanu angakuuzeni kuti musatenge fenofibrate.
  • Uzani dokotala ngati mumamwa kapena mumamwa mowa wambiri komanso ngati mwakhalapo ndi matenda ashuga kapena hypothyroidism (chithokomiro chosagwira ntchito).
  • Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Mukakhala ndi pakati mukatenga fenofibrate, itanani dokotala wanu.
  • Uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwa mukamamwa fenofibrate.

Idyani chakudya chochepa cha mafuta, cholesterol. Onetsetsani kuti mukutsatira zolimbitsa thupi komanso malingaliro azakudya zomwe adokotala anu kapena odyetsa. Mutha kuchezanso tsamba la National Cholesterol Education Program (NCEP) kuti mumve zambiri za zakudya pa http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.


Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Fenofibrate ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • kudzimbidwa
  • kutsegula m'mimba
  • kutentha pa chifuwa
  • kupweteka kumbuyo, mkono, kapena miyendo
  • mutu
  • kupweteka pamodzi

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo:

  • kupweteka kwa minofu, kufooka, kapena kukoma mtima; malungo
  • khungu kapena khungu
  • zidzolo; malungo; kuvuta kupuma; kusintha pokodza; kupweteka m'mimba
  • ming'oma
  • kupweteka kumtunda kwapakati pakati pa masamba amapewa kapena pansi pa phewa lamanja; kupweteka m'mimba, makamaka kumtunda chakumanja kwam'mimba; nseru; kusanza
  • kufiira, kutupa, kupweteka, kukoma, kapena kutentha mwendo umodzi
  • kupuma movutikira; kupweteka pamene akupuma; kutsokomola magazi
  • kutupa kwa nkhope, mmero, lilime, milomo, ndi maso; zovuta kumeza kapena kupuma; ukali

Fenofibrate ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa fenofibrate.


Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labotale kuti muwone yankho lanu ku fenofibrate.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

  • Antara®
  • Fenoglide®
  • Lipidil®
  • Lipofen®
  • Atatu®
  • Kusokoneza®
  • Zamgululi®

Chogulitsa ichi sichikupezeka pamsika. Njira zina zitha kupezeka.

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