Jekeseni wa Adalimumab

Zamkati

• Jekeseni wa Adalimumab imagwiritsidwa ntchito payokha kapena ndi mankhwala ena kuti athetse zizindikiritso zama autoimmune (momwe chitetezo cha mthupi chimagwirira mbali zathanzi za thupi ndikupweteka, kutupa, ndi kuwonongeka) kuphatikiza izi:
• Musanagwiritse ntchito jakisoni wa adalimumab,
• Jekeseni wa Adalimumab itha kubweretsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu nthawi yomweyo kapena pitani kuchipatala:

Kugwiritsa ntchito jakisoni wa adalimumab kumachepetsa kuthekera kwanu kothana ndi matenda ndikuchulukitsa mwayi woti mukhale ndi matenda akulu, kuphatikiza fungus, bakiteriya, ndi ma virus omwe amatha kufalikira mthupi. Matendawa angafunike kuthandizidwa kuchipatala ndipo atha kupha. Uzani dokotala wanu ngati nthawi zambiri mumakhala ndi matenda aliwonse kapena ngati muli kapena mukuganiza kuti mutha kukhala ndi matenda aliwonse pano. Izi zimaphatikizapo matenda ang'onoang'ono (monga mabala otseguka kapena zilonda), matenda omwe amabwera (monga zilonda zozizira) kapena matenda osachiritsika omwe samatha. Uzani dokotala wanu ngati mwakhalapo kapena munakhalapo ndi vuto lililonse lomwe limakhudza chitetezo chamthupi mwanu kapena ngati mumakhala kapena munakhalapo m'malo monga zigwa za Ohio kapena Mississippi komwe matenda ofala a fungus amapezeka kwambiri. Funsani dokotala wanu ngati simukudziwa ngati matendawa amapezeka kwambiri m'dera lanu. Uzani dokotala ngati mukumwa mankhwala omwe amachepetsa chitetezo cha mthupi monga awa: abatacept (Orencia), anakinra (Kineret), certolizumab (Cimzia), etanercept (Enbrel), golimumab (Simponi), infliximab (Remicade) , methotrexate (Otrexup, Rasuvo, Trexall), rituximab (Rituxan), kapena steroids monga dexamethasone, methylprednisolone (Medrol), prednisone (Rayos), kapena prednisolone (Prelone).

Dokotala wanu adzakuyang'anirani ngati muli ndi matendawa mukamalandira chithandizo chake. Ngati muli ndi zizindikiro zotsatirazi musanayambe kumwa mankhwala kapena ngati mukukumana ndi zizindikiro zotsatirazi mukamalandira chithandizo kapena mutangochoka kumene, pitani kuchipatala nthawi yomweyo: kufooka; thukuta; chikhure; chifuwa; kutsokomola ntchofu zamagazi; malungo; kuonda; kutopa kwambiri; kutsegula m'mimba; kupweteka m'mimba; khungu lofunda, lofiira, kapena lopweteka; kupweteka kovuta, kovuta, kapena pafupipafupi; kapena zizindikiro zina za matenda.

Mutha kukhala kuti mwadwala kale chifuwa chachikulu (TB; matenda owopsa am'mapapo) kapena hepatitis B (kachilombo kamene kamakhudza chiwindi) koma mulibe zizindikiro zilizonse za matendawa. Poterepa, jakisoni wa adalimumab akhoza kuonjezera chiopsezo kuti matenda anu adzakula kwambiri ndipo mudzakhala ndi zizindikilo. Dokotala wanu adzakuyesani khungu kuti muwone ngati muli ndi kachilombo ka TB kosagwira ntchito ndipo atha kuyitanitsa kuyesa magazi kuti muwone ngati muli ndi matenda a hepatitis B osagwira ntchito. Ngati ndi kotheka, dokotala wanu akhoza kukupatsani mankhwala ochizira matendawa musanayambe mankhwala anu ndi adalimumab. Uzani dokotala wanu ngati munakhalapo ndi TB kapena munakhalapo ndi TB, ngati munakhalako kapena munapitako kudziko kumene TB imafala, kapena ngati mwakhalapo ndi munthu amene ali ndi TB. Ngati muli ndi zizindikiro zotsatirazi za chifuwa chachikulu cha TB, kapena ngati muli ndi zina mwazizindikiro mukamalandira chithandizo, pitani kuchipatala mwachangu: chifuwa, kuchepa thupi, kuchepa kwa minofu, malungo, kapena thukuta usiku. Komanso itanani dokotala wanu nthawi yomweyo ngati muli ndi zina mwazizindikiro za matenda a chiwindi a B kapena ngati muli ndi zina mwazizindikiro mukalandira kapena mutalandira chithandizo: kutopa kwambiri, khungu lachikaso kapena maso, kusowa chilakolako chambiri, nseru kapena kusanza, kupweteka kwa minofu, mkodzo wamdima, matumbo ofiira dongo, malungo, kuzizira, kupweteka m'mimba, kapena zotupa.

Ana ena, achinyamata, komanso achikulire omwe adalandira jakisoni wa adalimumab kapena mankhwala ofanana nawo adayamba khansa yowopsa kapena yowopsa pamoyo kuphatikizapo lymphoma (khansa yomwe imayamba m'maselo omwe amalimbana ndi matenda). Achinyamata ena achikulire omwe adatenga adalimumab kapena mankhwala ofanana nawo adayamba ndi hepatosplenic T-cell lymphoma (HSTCL), khansa yoopsa kwambiri yomwe imayambitsa imfa m'kanthawi kochepa. Ambiri mwa anthu omwe adapanga HSTCL anali kuchiritsidwa ndi matenda a Crohn (matenda omwe thupi limagwiritsa ntchito gawo la m'mimba, kumayambitsa kupweteka, kutsegula m'mimba, kuchepa thupi, ndi malungo) kapena ulcerative colitis (vuto lomwe limayambitsa kutupa ndi zilonda. m'mbali mwa kholingo [matumbo akulu] ndi thumbo) ndi adalimumab kapena mankhwala ofanana nawo pamodzi ndi mankhwala ena otchedwa azathioprine (Imuran) kapena 6-mercaptopurine (Purinethol). Uzani dokotala wa mwana wanu ngati mwana wanu adakhalapo ndi khansa yamtundu uliwonse. Mwana wanu akayamba kudwala matendawa, itanani dokotala wake nthawi yomweyo: kupweteka m'mimba; malungo; kuwonda kosadziwika; zotupa zotupa pakhosi, pansi, kapena kubuula; kapena kuvulaza kosavuta kapena kutuluka magazi. Lankhulani ndi dokotala wa mwana wanu za kuopsa kobaya jakisoni wa adalimumab kwa mwana wanu.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba chithandizo ndi jakisoni wa adalimumab ndipo nthawi iliyonse yomwe mumalandira mankhwala. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito jakisoni wa adalimumab.

Jekeseni wa Adalimumab imagwiritsidwa ntchito payokha kapena ndi mankhwala ena kuti athetse zizindikiritso zama autoimmune (momwe chitetezo cha mthupi chimagwirira mbali zathanzi za thupi ndikupweteka, kutupa, ndi kuwonongeka) kuphatikiza izi:

• nyamakazi ya nyamakazi (momwe thupi limagwirira ziwalo zake, zimapweteka, kutupa, komanso kutayika kwa ntchito) mwa akulu,
• juvenile idiopathic arthritis (JIA; vuto lomwe limakhudza ana momwe thupi limagunda malo ake, kupweteketsa, kutupa, kutaya ntchito, ndikuchedwa kukula ndikukula) mwa ana azaka 2 kapena kupitirira,
• Matenda a Crohn (matenda omwe thupi limagwiritsa ntchito gawo la m'mimba, kumayambitsa kupweteka, kutsegula m'mimba, kuchepa thupi, ndi malungo) zomwe sizinasinthe mukamalandira mankhwala ena mwa akulu ndi ana azaka 6 kapena kupitirira,
• ulcerative colitis (vuto lomwe limayambitsa kutupa ndi zilonda mkatikati mwa matumbo [matumbo akulu] ndi rectum) pomwe mankhwala ena ndi chithandizo sizinathandize kapena sizingaloledwe kwa akulu ndi ana azaka 5 kapena kupitirira,
• ankylosing spondylitis (momwe thupi limagwirira malo olumikizirana mafupa a msana ndi madera ena omwe amayambitsa kupweteka ndi kuwonongeka kwamagulu) mwa akulu,
• psoriatic nyamakazi (vuto lomwe limayambitsa kupweteka kwamagulu ndi kutupa ndi masikelo pakhungu) mwa akulu,
• hidradenitis suppurativa (matenda apakhungu omwe amachititsa ziphuphu ngati zotupa m'makhwapa, kubuula, ndi kumatako) mwa akulu ndi ana azaka 12 kapena kupitirira,
• uveitis (kutupa ndi kutupa m'malo osiyanasiyana amaso) mwa akulu ndi ana azaka 2 kapena kupitirira,
• matenda a plaque psoriasis (matenda akhungu pomwe pamakhala zigamba zofiira, zotupa pamadera ena amthupi) mwa akulu.

Jekeseni ya Adalimumab ili mgulu la mankhwala otchedwa tumor necrosis factor (TNF) inhibitors. Zimagwira ntchito poletsa zochita za TNF, chinthu m'thupi chomwe chimayambitsa kutupa.

Jakisoni wa Adalimumab umabwera ngati yankho (madzi) ojambulira subcutaneously (pansi pa khungu). Dokotala wanu angakuuzeni kangati kuti mugwiritse ntchito adalimumab kutengera momwe mulili komanso msinkhu wanu. Kukuthandizani kukumbukira kukumbukira kubayira jakisoni wa adalimumab, onetsetsani masiku omwe muyenera kulandira pa kalendala yanu. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Gwiritsani ntchito jakisoni wa adalimumab monga momwe mwalamulira. Osamagwiritsa ntchito zocheperako kapena kuzigwiritsa ntchito pafupipafupi kuposa momwe adanenera dokotala.

Mukalandira mlingo wanu woyamba wa jakisoni wa adalimumab muofesi ya dokotala wanu. Pambuyo pake, mutha kubaya jakisoni wa adalimumab nokha kapena kukhala ndi mnzanu kapena wachibale kubayala. Musanagwiritse ntchito jakisoni wa adalimumab nthawi yoyamba, werengani malangizo olembedwa omwe amabwera nawo. Funsani dokotala wanu kapena wamankhwala kuti akuwonetseni kapena munthu yemwe ati adzalandire mankhwalawo momwe angabayire.

Jekeseni wa Adalimumab imabwera m'mitsempha yamafuta oyikika kale. Gwiritsani ntchito sirinji kapena cholembera kamodzi ndipo jekeseni yankho mu syringe kapena cholembera. Ngakhale mutakhalabe ndi yankho mu syringe kapena cholembera mutabaya, musabayenso. Tayani masirinji ndi zolembera zomwe mwazigwiritsa ntchito m'mbale zosagwira. Lankhulani ndi dokotala wanu kapena wamankhwala za momwe mungatayire chidebe chosagwira mankhwala.

Ngati mukugwiritsa ntchito sirinji kapena cholembera chomwe chakhala mufiriji, ikani syringe kapena cholembera pamalo osanja osachotsa kapu ya singano ndikulola kutentha kwa mphindi 15 mpaka 30 musanakonzekere kulandira mankhwala .Osayesa kutenthetsa mankhwalawo powotenthetsa mu microwave, ndikuwayika m'madzi otentha, kapena njira ina iliyonse.

Samalani kuti musagwetse kapena kuthyola ma syringe kapena zolembera za dosing. Zipangizozi zimapangidwa ndi magalasi kapena zimakhala ndi magalasi ndipo zimatha kusweka zikagwetsedwa.

Mutha kubaya jakisoni wa adalimumab paliponse patsogolo pa ntchafu kapena m'mimba kupatula mchombo wanu ndi malo awiri mainchesi (5 mainchesi) mozungulira. Kuti muchepetse mwayi wowawa kapena kufiira, gwiritsani ntchito tsamba lina la jakisoni aliyense. Perekani jakisoni aliyense kutalika kwa masentimita 2.5 kuchokera pamalo omwe mudagwiritsapo ntchito kale. Sungani mndandanda wa malo omwe munabayirapo jekeseni kuti musabayenso malo amenewa. Osalowetsa malo omwe khungu ndi lofewa, lophwanyika, lofiira, kapena lolimba kapena komwe muli ndi zipsera kapena zotambasula.

Nthawi zonse muziyang'ana njira ya jakisoni wa adalimumab musanaibayize. Onetsetsani kuti tsiku lotha ntchito silinadutse, kuti sirinji kapena cholembera cha dosing chili ndi madzi okwanira, komanso kuti madziwo ndi omveka komanso opanda mtundu. Musagwiritse ntchito sirinji kapena cholembera ngati chatha, ngati mulibe madzi okwanira, kapena ngati madziwo ali ndi mitambo kapena amakhala ndi ma flakes.

Kubayira kwa Adalimumab kumatha kuthandizira kuwongolera matenda anu koma sikungachiritse. Pitirizani kugwiritsa ntchito jakisoni wa adalimumab ngakhale mukumva bwino. Osasiya kugwiritsa ntchito jakisoni wa adalimumab osalankhula ndi dokotala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanagwiritse ntchito jakisoni wa adalimumab,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi jakisoni wa adalimumab, mankhwala ena aliwonse, kapena zosakaniza zilizonse za jakisoni wa adalimumab. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza. Ngati mukugwiritsa ntchito jakisoni woyambirira, uzani dokotala wanu ngati inu kapena munthu amene akukuthandizani kubaya jakisoni wa adalimumab ali ndi vuto la latex kapena labala.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchula mankhwala omwe adatchulidwa mu gawo la CHENJEZO CHENJEZO ndi zina mwa izi: cyclosporine (Gengraf, Neoral, Sandimmune), theophylline (Elixophyllin, Theo 24, Theochron), kapena warfarin (Coumadin, Jantoven). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• Kuphatikiza pa zomwe zatchulidwa mgawo la CHENJEZO LOFUNIKA, uzani adotolo ngati mwakhalapo ndi dzanzi kapena kumva kupweteka m'mbali iliyonse ya thupi lanu, matenda aliwonse omwe amakhudza dongosolo lanu lamanjenje, monga multiple sclerosis (matenda omwe misempha sagwira ntchito moyenera kuyambitsa kufooka, dzanzi, kuchepa kwa kulumikizana kwa minofu ndi mavuto ndi masomphenya, malankhulidwe, ndi kuwongolera chikhodzodzo), Guillain-Barré syndrome (kufooka, kumva kulira, ndi ziwalo zotheka chifukwa cha kuwonongeka kwamitsempha mwadzidzidzi), kapena optic neuritis (kutupa ya mitsempha yomwe imatumiza mauthenga kuchokera ku diso kupita ku ubongo); mtundu uliwonse wa khansa, matenda ashuga, kulephera kwa mtima, kapena matenda amtima. Ngati muli ndi psoriasis, uzani dokotala ngati mwalandira mankhwala opepuka.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa Mukakhala ndi pakati mukamagwiritsa ntchito jakisoni wa adalimumab, itanani dokotala wanu.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani adotolo kapena dokotala kuti mukugwiritsa ntchito jakisoni wa adalimumab.
• mulibe katemera popanda kulankhula ndi dokotala. Ngati mwana wanu akulandira jakisoni wa adalimumab, onetsetsani kuti mwana wanu walandira zipolopolo zonse zofunika kwa ana azaka zake asanayambe kulandira mankhwala ndi jakisoni wa adalimumab.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Jekeseni mlingo womwe mwaphonya mukangokumbukira. Kenako jekeseni mlingo wotsatira patsiku lanu lokonzedwa pafupipafupi. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musagwiritse ntchito mlingo wawiri kuti mupange omwe mwaphonya.

Jekeseni wa Adalimumab itha kubweretsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kufiira, kuyabwa, kuvulala, kupweteka, kapena kutupa pamalo omwe mudabaya jakisoni wa adalimumab
• nseru
• mutu
• kupweteka kwa msana

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu nthawi yomweyo kapena pitani kuchipatala:

• dzanzi kapena kumva kulasalasa
• mavuto ndi masomphenya
• kufooka kwa miyendo
• kupweteka pachifuwa
• kupuma movutikira
• zidzolo, makamaka zidzolo pamasaya kapena mikono yomwe imamva kuwala kwa dzuwa
• ululu wophatikizika watsopano
• ming'oma
• kuyabwa
• kutupa kwa nkhope, mapazi, akakolo, kapena miyendo yakumunsi
• kuvuta kupuma kapena kumeza
• malungo, zilonda zapakhosi, kuzizira, ndi zizindikiro zina za matenda
• kuvulaza kapena kutuluka mwachilendo
• khungu lotumbululuka
• chizungulire
• ofiira, amikanda kapena ziphuphu pakhungu

Akuluakulu omwe amalandira jakisoni wa adalimumab atha kukhala ndi khansa yapakhungu, lymphoma, ndi mitundu ina ya khansa kuposa anthu omwe salandila jakisoni wa adalimumab. Lankhulani ndi dokotala wanu za kuopsa kolandira mankhwalawa.

Jekeseni wa Adalimumab itha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamagwiritsa ntchito mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Sungani mu firiji ndikuteteza ku kuwala. Jakisoni wa Adalimumab amathanso kusungidwa kutentha kwapakati (mpaka 77 ° F [25 ° C]) mpaka masiku 14 ndikutetezedwa ku kuwala. Ngati jakisoni wa adalimumab amasungidwa kutentha kwa masiku opitilira 14 ndipo sakugwiritsidwa ntchito, ayenera kutayidwa. Osazizira. Chotsani mankhwala aliwonse oundana.

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu adzaitanitsa mayeso ena a labu asanadye, nthawi, komanso mutalandira chithandizo kuti muwone momwe thupi lanu likuyankhira kwa adalimumab.

Musalole kuti wina aliyense agwiritse ntchito mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Humira^® Jekeseni