Voriconazole

Zamkati

• Musanatenge voriconazole,
• Voriconazole imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi kapena izi zomwe zalembedwa mu ZISANGIZO ZAPADERA, itanani dokotala wanu mwachangu:
• Zizindikiro za bongo zingaphatikizepo izi:

Voriconazole imagwiritsidwa ntchito kwa achikulire ndi ana azaka ziwiri kapena kupitilira apo kuti athetse matenda akulu a mafangasi monga aspergillosis wowopsa (matenda am'fungasi omwe amayamba m'mapapu ndikufalikira kudzera m'magazi kupita ku ziwalo zina), esophageal candidiasis (yisiti [mtundu wa fungus] matenda omwe amatha kuyambitsa zigamba zoyera mkamwa ndi kukhosi), ndi candidemia (matenda a fungus m'magazi). Amagwiritsidwanso ntchito pochiza matenda ena a mafangasi pomwe mankhwala ena sangagwire ntchito kwa odwala ena. Voriconazole ali mgulu la mankhwala oletsa mafungal otchedwa triazoles. Zimagwira ntchito pochepetsa kukula kwa bowa komwe kumayambitsa matenda.

Voriconazole amabwera ngati piritsi komanso kuyimitsidwa (madzi) kuti atenge pakamwa. Nthawi zambiri amatengedwa maola 12 aliwonse osadya kanthu, ola limodzi musanadye kapena ola limodzi mutadya. Kukuthandizani kukumbukira kukumbukira kutenga voriconazole, tengani mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani voriconazole ndendende monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Ngati mukumira kuyimitsidwa kwa voriconazole, sinthani botolo lotsekedwa kwa pafupifupi masekondi 10 musanagwiritse ntchito kusakaniza mankhwala mofanana. Osasakaniza kuyimitsidwa ndi mankhwala ena aliwonse, madzi, kapena madzi aliwonse. Nthawi zonse gwiritsani ntchito chida choyezera chomwe chimabwera ndi mankhwala anu. Simungalandire mankhwala okwanira ngati mutagwiritsa ntchito supuni ya banja kuti muyese mlingo wanu.

Kumayambiriro kwa chithandizo chanu, mutha kulandira voriconazole mwa jakisoni (mu mtsempha). Mukayamba kumwa voriconazole pakamwa, dokotala wanu akhoza kukuyambitsani pamlingo wochepa ndikuwonjezerani mlingo wanu ngati mkhalidwe wanu sukusintha. Dokotala wanu amathanso kuchepetsa mlingo wanu ngati mukumva zovuta kuchokera ku voriconazole.

Kutalika kwa chithandizo chanu kumadalira thanzi lanu lonse, mtundu wa matenda omwe muli nawo, komanso momwe mumayankhira mankhwalawo. Pitilizani kumwa voriconazole ngakhale mukumva bwino. Osasiya kumwa voriconazole osalankhula ndi dokotala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge voriconazole,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la voriconazole, mankhwala ena oletsa mafungal monga fluconazole (Diflucan), itraconazole (Onmel, Sporanox), kapena ketoconazole (Nizoral); mankhwala ena aliwonse, lactose, kapena zina zilizonse pazapiritsi za voriconazole ndi kuyimitsidwa. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza zamapiritsi a voriconazole ndikuyimitsidwa.
• musamamwe voriconazole ngati mukumwa mankhwala aliwonse awa: carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); cisapride (Propulsid); efavirenz (Sustiva, ku Atripla); mankhwala amtundu wa ergot monga dihydroergotamine (DHE 45, Migranal), ergoloid mesylates (Hydergine), ergotamine (Ergomar, ku Cafergot, ku Migergot), ndi methylergonovine (Methergine); ivabradine (Corlanor); naloxegol (Monvatik); phenobarbital; pimozide (Orap); quinidine (mu Nuedexta); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, ku Rifamate, ku Rifater); ritonavir (Norvir, ku Kaletra); mankhwala (Rapamune); Chingwe cha St. tolvaptan (Jynarque, Samsca); ndi venetoclax (Venclexta).
• Uzani dokotala ndi wazamankhwala mankhwala ena omwe mumalandira, mavitamini, ndi zakudya zina zomwe mumamwa. Onetsetsani kuti mwatchulapo izi: maanticoagulants ('opopera magazi') monga warfarin (Coumadin, Jantoven); benzodiazepines monga alprazolam (Niravam, Xanax), midazolam, ndi triazolam (Halcion); calcium blockers monga amlodipine (Norvasc, ku Amturnide, ku Tekamlo), felodipine (Plendil), isradipine, nicardipine (Cardene), nifedipine (Adalat, Afeditab, Procardia), nimodipine (Nymalize), ndi nisoldipine (Sular); mankhwala ochepetsa mafuta m'thupi (ma statins) monga atorvastatin (Lipitor, ku Caduet, ku Liptruzet), fluvastatin (Lescol), lovastatin (Altoprev, ku Advicor), pravastatin (Pravachol), ndi simvastatin (Zocor, ku Simcor, ku Vytorin); cyclosporine (Gengraf, Neoral, Sandimmune); everolimus (Wothandizira, Zortress); fentanyl (Abstral, Actiq, Fentora, Lazanda, Subsys); mankhwala a shuga monga glipizide (Glucotrol), glyburide (Diabeta, Glynase,, in Glucovance), ndi tolbutamide; mankhwala a HIV monga delavirdine (Rescriptor), nelfinavir (Viracept), nevirapine (Viramune), ndi saquinavir (Invirase); methadone (Dolophine, Methadose); mankhwala oletsa anti-inflammatory (diclofenac, ibuprofen), njira zolera zam'kamwa; oxycodone (Oxecta, Oxycontin, ku Oxycet, ku Percocet, ku Percodan, ku Roxicet, ku Xartemis); phenytoin (Dilantin, Phenytek); proton-pump inhibitors monga esomeprazole (Nexium, ku Vimovo), lansoprazole (Prevacid), omeprazole (Prilosec, ku Prevpac), pantoprazole (Protonix), ndi rabeprazole (AcipHex); tacrolimus (Astagraf, Prograf); vinblastine; ndi vincristine. Mankhwala ena ambiri amathanso kulumikizana ndi voriconazole, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• auzeni dokotala ngati mwalandira mankhwala a chemotherapy a khansa, komanso ngati mwakhalapo ndi nthawi yayitali ya QT (vuto la mtima losowa lomwe lingayambitse kugunda kwamtima, kukomoka, kapena kufa mwadzidzidzi), kapena ngati muli ndi anayamba kugunda pang'onopang'ono kapena mosasinthasintha, potaziyamu, magnesium, kapena calcium, magazi, (mtima wokulitsidwa kapena wokutidwa wa mtima womwe umaletsa mtima kupopa magazi mwachizolowezi), khansa yamagazi, kusagwirizana kwa galactose kapena glucose-galactose malabsorption ( zinthu zobadwa nazo pomwe thupi sililekerera lactose); vuto lililonse lomwe limakupangitsani kukhala kovuta kukumba sucrose (shuga wa patebulo) kapena lactose (yomwe imapezeka mkaka ndi zopangira mkaka), kapena matenda a chiwindi kapena impso.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Simuyenera kutenga pakati mukamamwa voriconazole. Muyenera kugwiritsa ntchito njira yolerera yothandiza kupewa mimba mukamamwa mankhwala ndi voriconazole. Lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Mukakhala ndi pakati mukatenga voriconazole, itanani dokotala wanu mwachangu. Voriconazole atha kuvulaza mwana wosabadwayo.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani adotolo kapena dokotala kuti mukumwa voriconazole.
• muyenera kudziwa kuti voriconazole imatha kuyambitsa masomphenya kapena zovuta zina ndi maso anu ndipo imatha kupangitsa kuti maso anu azindikire kuwala. Osayendetsa galimoto usiku mutatenga voriconazole. Osayendetsa galimoto masana kapena kugwiritsa ntchito makina ngati muli ndi vuto ndi masomphenya anu mukamamwa mankhwalawa.
• konzekerani kupeŵa kuwunika kwa dzuwa kosafunikira kapena kwanthawi yayitali komanso kuvala zovala zoteteza, magalasi a dzuwa, ndi zoteteza ku dzuwa. Voriconazole imatha kupangitsa khungu lanu kuzindikira kuwala kwa dzuwa.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Voriconazole imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• masomphenya achilendo
• zovuta kuwona mitundu
• kutsegula m'mimba
• nseru
• kusanza
• mutu
• chizungulire
• pakamwa pouma
• kuchapa

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi kapena izi zomwe zalembedwa mu ZISANGIZO ZAPADERA, itanani dokotala wanu mwachangu:

• malungo
• kuzizira kapena kunjenjemera
• kugunda kwamtima mwachangu
• kupuma mofulumira
• chisokonezo
• kukhumudwa m'mimba
• kutopa kwambiri
• kuvulaza kapena kutuluka mwachilendo
• kusowa chilakolako
• kuyabwa, mkodzo wakuda, kusowa kwa njala, kutopa, chikasu pakhungu kapena maso, kupweteka kumtunda kwakumimba, nseru, kusanza, kapena zizindikiritso zonga chimfine
• kutopa; kusowa mphamvu; kufooka; nseru; kusanza; chizungulire; kuonda, kapena kupweteka m'mimba
• kunenepa; mafuta onenepa pakati pa mapewa; nkhope yozungulira (nkhope yamwezi); kuda kwa khungu m'mimba, ntchafu, mabere, ndi mikono; khungu lochepera; kuvulaza; kukula kwambiri kwa tsitsi; kapena thukuta
• kuyerekezera zinthu m'maganizo (kuwona zinthu kapena kumva mawu omwe kulibe)
• kupweteka pachifuwa kapena kulimba
• zidzolo
• thukuta
• ming'oma kapena khungu
• kuvuta kupuma kapena kumeza
• kutupa kwa manja, mapazi, akakolo, kapena miyendo yakumunsi

Voriconazole imatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Sungani mapiritsi kutentha kwa firiji komanso kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa). Sungani kuyimitsidwa kosakanikirana m'kamwa mufiriji, koma mukasakaniza muzisunga kutentha ndikuti musaziziziritse. Chotsani kuyimitsidwa kulikonse komwe sikugwiritsidwe ntchito pakatha masiku 14.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• kutengeka ndi kuwala
• kukulitsa ophunzira (mabwalo akuda pakati pa maso)
• maso otseka
• kutsitsa
• kutayika bwino pamene mukuyenda
• kukhumudwa
• kupuma movutikira
• kugwidwa
• kutupa m'mimba
• kutopa kwambiri

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira voriconazole.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu. Ngati muli ndi zizindikiro za matenda mukamaliza voriconazole, itanani dokotala wanu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Vfend^®