Tipranavir

Zamkati

• Musanatenge tipranavir,
• Tipranavir angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

Tipranavir (yotengedwa ndi ritonavir [Norvir]) itha kuyambitsa magazi muubongo. Matendawa akhoza kukhala owopsa. Uzani dokotala wanu ngati mwangopanga kumene opaleshoni, kapena ngati mwavulala posachedwa mwanjira iliyonse. Komanso, uzani dokotala wanu ngati muli ndi vuto lakutuluka magazi monga hemophilia (momwe magazi samaphimbira bwino). Uzani dokotala wanu komanso wamankhwala ngati mukumwa mankhwala aliwonse awa: anticoagulants ('magazi opopera magazi') monga warfarin (Coumadin, Jantoven), aspirin kapena mankhwala okhala ndi aspirin, cilostazol, clopidogrel (Plavix), dipyridamole (Persantine, mu Aggrenox ), eptifibatide (Integrilin), heparin, nonsteroidal anti-inflammatory drugs (ibuprofen, naproxen), prasugrel (Effient), ticlopidine, kapena tirofiban (Aggrastat). Muyeneranso kuuza dokotala komanso wamankhwala ngati mukumwa vitamini E, kupatula kuchuluka komwe kumapezeka mu multivitamin yatsiku ndi tsiku. Ngati mukufuna kulandira chithandizo mwadzidzidzi pazifukwa zilizonse, onetsetsani kuti muwauze madotolo onse omwe amakuchitirani kuti mukumwa tipranavir. Itanani dokotala wanu nthawi yomweyo ngati mwakumana ndi zipsera zachilendo kapena magazi mukamalandira mankhwala a tipranavir.

Tipranavir (yotengedwa ndi ritonavir [Norvir]) itha kuwononga chiwindi chomwe chitha kupha moyo. Uzani dokotala wanu ngati mwakhalapo ndi hepatitis (kutupa kwa chiwindi choyambitsidwa ndi kachilombo), matenda ena aliwonse a chiwindi, kapena ngati mumamwa kapena mumamwa mowa. Ngati mukumane ndi zizindikiro izi, lekani kumwa mankhwala a tipranavir ndipo itanani dokotala nthawi yomweyo: kutopa; kufooka; zizindikiro ngati chimfine; kusowa chilakolako; nseru; kusanza; kupweteka, kupweteka, kutupa, kapena kukhudzika kumanja kwanu pansi pa nthiti zanu; chikasu cha khungu kapena maso; mkodzo wakuda (tiyi); kapena matumbo otumbululuka.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena kuti aone momwe thupi lanu likuyankhira ku tipranavir.

Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito tipranavir.

Tipranavir imagwiritsidwa ntchito ndi ritonavir (Norvir) ndi mankhwala ena kuti athetse kachilombo ka HIV. Tipranavir ali mgulu la mankhwala otchedwa protease inhibitors. Zimagwira ntchito pochepetsa kuchuluka kwa kachilombo ka HIV m'magazi. Ngakhale tipranavir sichitha kachilombo ka HIV, imatha kuchepetsa mwayi wanu wopeza matenda a immunodeficiency syndrome (AIDS) ndi matenda okhudzana ndi HIV monga matenda akulu kapena khansa. Kumwa mankhwalawa pamodzi ndi kugonana mosatekeseka ndikusintha zina pamoyo wanu kumachepetsa chiopsezo chotenga kachirombo ka HIV kwa anthu ena.

Tipranavir imabwera ngati kapisozi komanso njira yothetsera pakamwa (madzi) kuti mutenge pakamwa. Ngati tipranavir atengedwa ndi makapisozi a ritonavir kapena yankho, nthawi zambiri amakhala kawiri patsiku ndi chakudya kapena wopanda chakudya. Ngati tipranavir imamwa ndi mapiritsi a ritonavir, nthawi zambiri imakhala kawiri patsiku ndi chakudya. Tengani tipranavir ndi ritonavir mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani tipranavir ndendende monga mwalamulo. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Musatenge tipranavir popanda ritonavir.

Kumeza makapisozi lonse; musatafune kapena kuwaphwanya. Ngati mukulephera kumeza makapisozi, uzani dokotala kapena wamankhwala.

Tipranavir imathandiza kuchepetsa kufala kwa kachirombo ka HIV koma sikuchiza. Pitirizani kumwa tipranavir ngakhale mukumva bwino. Musaleke kumwa tipranavir osalankhula ndi dokotala. Mukasiya kumwa tipranavir kapena kudumpha mlingo, matenda anu akhoza kukhala ovuta kuchiza. Pamene mankhwala anu a tipranavir ayamba kuchepa, pezani zambiri kuchokera kwa dokotala kapena wamankhwala.

Funsani dokotala wanu kapena wamankhwala kuti mupeze zambiri za wopanga kwa wodwalayo. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge tipranavir,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi matupi awo sagwirizana ndi tipranavir, ritonavir (Norvir, ku Kaletra), mankhwala a sulfa, mankhwala ena aliwonse, kapena chilichonse chopezeka mu makapisozi a tipranavir kapena yankho. Funsani wamankhwala wanu ngati simukudziwa ngati mankhwala omwe simukugwirizana nawo ndi mankhwala a sulfa. Komanso, funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza zam'mapiritsi a tipranavir kapena yankho.
• Uzani dokotala ngati mukumwa mankhwala aliwonse otsatirawa kapena mankhwala azitsamba: alfuzosin (Uroxatral); cisapride (Propulsid) (sichikupezeka ku U.S.); mankhwala a ergot a migraines monga dihydroergotamine (DHE 45, Migranal), ergoloid mesylate (Hydergine), ergotamine (Ergomar, Cafergot, ku Migergot, ena), kapena methylergonovine (Methergine); mankhwala ena osagunda pamtima kuphatikiza amiodarone (Nexterone, Pacerone), flecainide, propafenone (Rythmol), kapena quinidine (ku Nuedexta); lovastatin (Altoprev), lurasidone (Latuda); midazolam pakamwa; pimozide (Orap); rifampin (Rifadin, Rimactane, ku Rifamate, ku Rifater); sildenafil (Revatio) yothandizira matenda oopsa a m'mapapo mwanga, simvastatin (Zocor, ku Vytorin); Chingwe cha St. ndi triazolam (Halcion). Dokotala wanu angakuuzeni kuti musatenge tipranavir ngati mukumwa mankhwala amodzi kapena angapo.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo mankhwala omwe atchulidwa mgawo la CHENJEZO LACHENJEZO ndi izi: mankhwala oletsa mafungulo monga fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole (Extina, Nizoral, Xolegel), kapena voriconazole (Vfend); boceprevir (sakupezekanso ku US; Victrelis); chifuwa (Tracleer); zotsekera ma calcium-calcium monga diltiazem (Cardizem, Cartia, Diltzac, Taztia, Tiazac, ena), felodipine, nicardipine, nisoldipine (Sular), kapena verapamil (Calan, Covera, Verelan, ena); mankhwala ochepetsa mafuta m'thupi ('statins') monga atorvastatin (Lipitor, ku Caduet) ndi rosuvastatin (Crestor); clarithromycin (Biaxin, mu Prevpac); colchicine (Colcrys, Mitigare, mu Col-Probenecid); desipramine (Norpramin); disulfiram (Antabuse); estrogen hormone mankhwala othandizira; fluticasone (Flonase, Flovent, ku Advair, ku Dymista); ma immunosuppressants monga cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), kapena tacrolimus (Astagraf, Envarsus XR, Prograf, ena); mankhwala a shuga monga glimepiride (Amaryl, ku Duetact), glipizide (Glucotrol), glyburide (Diabeta, Glynase, ena), pioglitazone (Actos, ku Actoplus Met, ku Duetact, ku Oseni), repaglinide (Prandin, ku Prandimet), kapena tolbutamide; mankhwala ena osagwira erectile kuphatikizapo sildenafil (Viagra), tadalafil (Adcirca, Cialis), kapena vardenafil (Levitra, Staxyn); Mankhwala ena ogwidwa kuphatikizapo carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), phenobarbital, phenytoin (Dilantin, Phenytek), ndi valproic acid (Depakene); Mankhwala ena a HIV kuphatikiza abacavir (Ziagen, ku Epzicom, ku Trizivir), atazanavir (Reyataz, ku Evotaz), dolutegravir (Tivicay, ku Juluca), enfuvirtide (Fuzeon); etravirine (Kutengeka); fosamprenavir (Lexiva), lopinavir (ku Kaletra), raltegravir (Isentress), ndi saquinavir (Invirase); meperidine (Demerol); methadone (Dolophine, Methadose); metronidazole (Flagyl, ku Pylera); omeprazole (Prilosec, ku Zegerid); quetiapine (Seroquel); rifabutin (Mycobutin); salmeterol (Serevent, ku Advair); serotonin reuptake inhibitors (SSRIs) monga fluoxetine (Prozac, Sarafem, Selfemra, mu Symbyax), paroxetine (Brisdelle, Paxil, Pexeva), kapena sertraline (Zoloft); telaprevir (sichikupezeka ku US; Incivek); ndi trazodone. Mankhwala ena ambiri amathanso kulumikizana ndi tipranavir, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu. Onetsetsani kuti mwalankhula ndi dokotala kapena wamankhwala musanayambe kumwa mankhwala atsopano mukamalandira mankhwala a tipranavir. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• ngati mukumwa didanosine (Videx), imwani maola awiri musanatenge mankhwala a tipranavir.
• ngati mukumwa maantacid, tengani ola limodzi musanatenge kapena 2 maola mutamwa tipranavir.
• uzani dokotala wanu ngati mwakhalapo ndi matenda ashuga kapena shuga wambiri; cholesterol yamagazi kapena triglycerides (mafuta amwazi); kapena matenda omwe amabwera ndikudutsa monga chifuwa chachikulu (TB), cytomegalovirus (CMV), herpes, Mycobacterium avium, shingles, kapena chibayo.
• muyenera kudziwa kuti anthu ena omwe ali ndi matenda a shuga amayamba kukulira matenda ashuga akamamwa tipranavir. Ngati muli ndi matenda ashuga, ndikofunikira kuwunika mosamala magazi anu mukamamwa mankhwala a tipranavir ndikuyimbira dokotala ngati shuga lanu lamagazi likuvuta kulamulira. Dokotala wanu angafunike kusintha mankhwala anu ashuga kapena kukupatsani mankhwala atsopano kuti muchepetse shuga wanu wamagazi.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga tipranavir, itanani dokotala wanu. Osamayamwa ngati muli ndi kachilombo ka HIV kapena mukumwa tipranavir.
• muyenera kudziwa kuti tipranavir imachepetsa kugwira ntchito kwa njira zolerera za mahomoni (mapiritsi oletsa kubereka, zigamba, mphete, ndi jakisoni). Muyenera kugwiritsa ntchito njira ina yolerera popewa kutenga mimba mukamamwa mankhwala a tipranavir. Lankhulani ndi dokotala wanu za njira zina zopewera kutenga mimba mukamamwa mankhwalawa.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa tipranavir.
• konzekerani kupeŵa kuwunika kwa dzuwa kosafunikira kapena kwanthawi yayitali komanso kuvala zovala zoteteza, magalasi a dzuwa, ndi zoteteza ku dzuwa. Tipranavir imatha kupangitsa khungu lanu kuzindikira kuwala kwa dzuwa.
• muyenera kudziwa kuti mafuta anu amthupi amatha kuchuluka kapena kusunthira mbali zosiyanasiyana za thupi lanu monga kumbuyo kwa khosi lanu ndi mapewa apamwamba ('njati hump'), m'mimba, ndi mabere. Thupi lanu limatha kutaya mafuta m'manja, miyendo, nkhope, ndi matako. Lankhulani ndi dokotala ngati muwona kusintha kulikonse kwamafuta anu.
• muyenera kudziwa kuti mutha kukhala ndi hyperglycemia (kuchuluka kwa shuga m'magazi anu) mukamamwa mankhwalawa, ngakhale mulibe matenda ashuga. Uzani dokotala wanu nthawi yomweyo ngati muli ndi zizindikiro izi mukamamwa mankhwala a tipranavir: ludzu kwambiri, kukodza pafupipafupi, njala yayikulu, kusawona bwino, kapena kufooka. Ndikofunika kuyimbira dokotala wanu mukangomva izi, chifukwa shuga wambiri yemwe samalandira mankhwala amatha kuyambitsa vuto lalikulu lotchedwa ketoacidosis. Ketoacidosis imatha kukhala pangozi ngati singachiritsidwe koyambirira. Zizindikiro za ketoacidosis zimaphatikizira pakamwa pouma, nseru ndi kusanza, kupuma movutikira, mpweya womwe umanunkhira zipatso, ndikuchepetsa chidziwitso.
• muyenera kudziwa kuti pamene mukumwa mankhwala ochizira kachilombo ka HIV, chitetezo chanu cha mthupi chingakhale champhamvu ndikuyamba kulimbana ndi matenda ena omwe anali kale mthupi lanu. Izi zitha kukupangitsani kukhala ndi zizindikilo za matendawa. Ngati muli ndi zizindikiro zatsopano kapena zowonjezereka nthawi iliyonse mukamamwa mankhwala a tipranavir, onetsetsani kuti mwauza dokotala.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo wosowa pamodzi ndi ritonavir mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Tipranavir angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutsegula m'mimba
• kuonda
• mutu
• kupweteka m'mimba

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

• malungo, kuzizira, chifuwa, kapena zizindikiro zina za matenda
• zidzolo
• kufiira, kuphulika, kapena khungu
• kuyabwa
• kukhazikika pakhosi
• kupuma movutikira
• kufooka, kuchita dzanzi ndi kupweteka, m'manja ndi m'mapazi
• kuvuta kupuma kapena kumeza
• kupweteka kwa minofu kapena molumikizana kapena kuuma

Tipranavir angayambitse mavuto ena. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Sungani mabotolo osatsegulidwa a makapisozi a tipranavir mufiriji. Sungani mabotolo otseguka a makapisozi a tipranavir kutentha, komanso kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa). Sungani yankho la tipranavir kutentha. Osazizira kapena kuyimitsa yankho la tipranavir. Chongani tsiku inu kutsegula botolo la tipranavir pa chizindikiro; ngati mankhwalawo sakugwiritsidwa ntchito pasanathe masiku 60, tsitsani mankhwala otsalawo.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira ku tipranavir.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Aptivus^®