Jekeseni wa Ondansetron

Zamkati

• Musanagwiritse ntchito ondansetron,
• Ondansetron ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo kapena pitani kuchipatala mwadzidzidzi:
• Zizindikiro za bongo zingaphatikizepo:

Jekeseni wa Ondansetron imagwiritsidwa ntchito popewa kunyowa ndi kusanza komwe kumachitika chifukwa cha chemotherapy ya khansa komanso opaleshoni. Ondansetron ali mgulu la mankhwala otchedwa serotonin 5-HT₃ otsutsana nawo. Zimagwira ntchito poletsa serotonin, chinthu chachilengedwe chomwe chingayambitse kusanza ndi kusanza.

Ondansetron amabwera ngati yankho (madzi) kuti alowe jakisoni (mumtsempha) kapena mu mnofu (mu minofu) ndi othandizira azaumoyo kuchipatala kapena kuchipatala. Ondansetron akagwiritsidwa ntchito popewa kunyoza komanso kusanza komwe kumachitika chifukwa cha chemotherapy, nthawi zambiri amapatsidwa mphindi 30 chemotherapy isanayambe. Mlingo wowonjezerapo ungaperekedwe patatha maola 4 mutamwa mankhwala oyamba a ondansetron ndi maola 8 mutatha mlingo woyamba wa ondansetron, ngati kuli kofunikira. Ondansetron akagwiritsidwa ntchito popewa mseru ndi kusanza komwe kumachitika chifukwa cha opaleshoni, nthawi zambiri amaperekedwa atangotsala pang'ono kuchitidwa opaleshoni. Ondansetron amaperekedwanso pambuyo pochitidwa opaleshoni kwa odwala omwe akukumana ndi nseru ndi kusanza komanso omwe sanalandire ondansetron asanachite opareshoni.

Mankhwalawa amatha kupatsidwa ntchito zina. Funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanagwiritse ntchito ondansetron,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi ondansetron, alosetron (Lotronex), dolasetron (Anzemet), granisetron (Kytril), palonosetron (Aloxi), kapena mankhwala ena aliwonse: kapena china chilichonse chophatikizira jakisoni wa ondansetron. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• uzani dokotala wanu ngati mukulandira apomorphine (Apokyn). Dokotala wanu angakuuzeni kuti musagwiritse ntchito ondansetron ngati mukulandira mankhwalawa.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: amiodarone (Cordarone, Pacerone); azithromycin (Zithromax); mankhwala ena ogwidwa monga carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), kapena phenytoin (Dilantin); chloroquine (Aralen); mankhwala enaake; citalopram (Celexa); clarithromycin (Biaxin, mu Prevpac); okodzetsa ('mapiritsi amadzi'); erythromycin (EES, Erythrocin, ena); fentanyl (Abstral, Actiq, Duragesic, Fentora, Lazanda, Onsolis, Subsys); ntchentche; haloperidol (Haldol); lifiyamu (Lithobid); mankhwala ochizira migraines monga almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), ndi zolmitriptan (Zomig); methylene buluu; mirtazapine (Remeron); monoamine oxidase (MAO) inhibitors kuphatikiza isocarboxazid (Marplan), linezolid (Zyvox), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), ndi tranylcypromine (Parnate); moxifloxacin (Avelox); pentamidine (Nebu-Pent); pimozide (Orap); kupeza; quinidine; rifampin (Rifadin, Rimactane, ku Rifamate, ku Rifater); serotonin / norepinephrine reuptake inhibitors (SNRIs) monga desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), ndi venlafaxine (Effexor XR); serotonin reuptake inhibitors (SSRIs) monga citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, mu Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), ndi sertraline (Zoloft); sotalol (Betapace, Sorine); thioridazine; tramadol (Conzip, Ultram, mu Ultracet); ndi vandetanib (Caprelsa). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala pazotsatira. Mankhwala ena ambiri amathanso kulumikizana ndi ondansetron, onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• auzeni adotolo ngati inu kapena wina aliyense m'banja mwanu adakhalapo kapena adakhalapo ndi matenda a QT (zomwe zimawonjezera chiwopsezo chokhala ndi kugunda kwamtima kosafunikira komwe kumatha kukomoka kapena kufa mwadzidzidzi), kapena mtundu wina wamatenda osakhazikika pamtima kapena vuto la kugunda kwamtima, kapena ngati mwakhalapo ndi magnesium kapena potaziyamu wambiri m'magazi anu, kulephera kwa mtima (HF; momwe mtima sungapope magazi okwanira mbali zina za thupi), kapena matenda a chiwindi.
• uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukalandira ondansetron, itanani dokotala wanu.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumakonda kudya.

Ondansetron ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• mutu
• kudzimbidwa
• Kusinza
• kumva kuzizira kapena kuzizira
• kupweteka, kuwotcha, kuchita dzanzi, kapena kumva kupweteka m'manja kapena m'mapazi
• malungo
• kupweteka kwa tsamba la jakisoni, kufiira, kutupa, kutentha, kapena kutentha

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo kapena pitani kuchipatala mwadzidzidzi:

• zidzolo
• ming'oma
• kuyabwa
• kutupa kwa maso, nkhope, milomo, lilime, mmero, manja, mapazi, akakolo, kapena miyendo yakumunsi
• ukali
• kuvuta kupuma kapena kumeza
• kupweteka pachifuwa
• kupuma movutikira
• chizungulire, kupepuka, kapena kukomoka
• kuthamanga, kuchepa kapena kusakhazikika kwamtima
• kusawona bwino kapena kutaya masomphenya
• wamisala
• kubvutika
• kuyerekezera zinthu m'maganizo (kuwona zinthu kapena kumva mawu omwe kulibe)
• malungo
• thukuta kwambiri
• chisokonezo
• nseru, kusanza, kapena kutsegula m'mimba
• kutayika kwa mgwirizano
• zolimba kapena zopindika minofu
• kugwidwa
• chikomokere (kutaya chidziwitso)

Ondansetron ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamagwiritsa ntchito mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Mankhwalawa amasungidwa kuchipatala kapena kuchipatala.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

• kutaya mwadzidzidzi masomphenya kwakanthawi kochepa
• chizungulire kapena mutu wopepuka
• kukomoka
• kudzimbidwa
• kugunda kwamtima kosasinthasintha

Sungani maimidwe onse ndi dokotala wanu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Zofran^® Jekeseni