Mlembi: Marcus Baldwin
Tsiku La Chilengedwe: 20 Kuni 2021
Sinthani Tsiku: 19 Novembala 2024
Anonim
How does sitagliptin work? DPP-4 inhibitors and GLP-1 mimetics
Kanema: How does sitagliptin work? DPP-4 inhibitors and GLP-1 mimetics

Zamkati

Sitagliptin imagwiritsidwa ntchito limodzi ndi zakudya komanso masewera olimbitsa thupi ndipo nthawi zina ndimankhwala ena ochepetsa shuga m'magazi mwa achikulire omwe ali ndi matenda a shuga a mtundu wachiwiri (momwe shuga wamagazi amakhala wochuluka kwambiri chifukwa thupi silimapanga kapena kugwiritsa ntchito insulini mwachizolowezi). Sitagliptin ali mgulu la mankhwala otchedwa dipeptidyl peptidase-4 (DPP-4) inhibitors. Zimagwira ntchito pakuwonjezera kuchuluka kwa zinthu zina zachilengedwe zomwe zimachepetsa shuga m'magazi ukakhala wokwera. Sitagliptin sichigwiritsidwa ntchito pochiza matenda amtundu woyamba 1 (momwe thupi silimatulutsira insulin motero silingathe kuwongolera kuchuluka kwa shuga m'magazi).

Popita nthawi, anthu omwe ali ndi matenda ashuga komanso shuga wambiri m'magazi amatha kukhala ndi mavuto owopsa kapena owopsa, kuphatikizapo matenda amtima, sitiroko, mavuto a impso, kuwonongeka kwa mitsempha, komanso mavuto amaso. Kumwa mankhwala (mankhwala), kusintha moyo wanu (mwachitsanzo, zakudya, kuchita masewera olimbitsa thupi, kusiya kusuta), komanso kuwunika shuga wanu wamagazi pafupipafupi kungakuthandizeni kuthana ndi matenda anu ashuga komanso kukhala ndi thanzi labwino. Mankhwalawa amathanso kuchepetsa mwayi wokhala ndi vuto la mtima, sitiroko, kapena zovuta zina zokhudzana ndi matenda ashuga monga impso kulephera, kuwonongeka kwamitsempha (dzanzi, miyendo yozizira kapena mapazi; kuchepa kwa kugonana kwa amuna ndi akazi), mavuto amaso, kuphatikiza kusintha kutaya masomphenya, kapena matenda a chiseyeye. Dokotala wanu ndi ena othandizira zaumoyo adzakambirana nanu za njira yabwino yothetsera matenda anu ashuga.


Sitagliptin imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku kapena wopanda chakudya. Tengani sitagliptin mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani sitagliptin ndendende monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Sitagliptin imathandiza kuchepetsa shuga wambiri koma sichiritsa matenda ashuga. Pitirizani kutenga sitagliptin ngakhale mukumva bwino. Osasiya kumwa sitagliptin osalankhula ndi dokotala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge sitagliptin,

  • uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la sitagliptin kapena mankhwala ena aliwonse.
  • Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: digoxin (Lanoxicaps, Lanoxin); insulini; ndi mankhwala ena apakamwa a shuga kuphatikizapo acetohexamide, chlorpropamide (Diabinese), glimepiride (Amaryl), glipizide (Glucotrol, ku Metaglip), glyburide (Diabeta, Glycron, Micronase), tolazamide (Tolinase), ndi tolbutamide. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
  • Uzani dokotala ngati mumamwa kapena mumamwa mowa wambiri komanso ngati mwakhalapo ndi matenda ashuga ketoacidosis (vuto lalikulu lomwe limachitika shuga wa magazi atakwera kwambiri), kapamba (kutupa kwa kapamba), ndulu, kuchuluka kwa triglycerides (mafuta) m'magazi anu, kulephera kwa mtima, kapena matenda a impso.
  • Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga sitagliptin, itanani dokotala wanu.
  • ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani adotolo kapena dokotala kuti mukumwa sitagliptin.
  • lankhulani ndi dokotala wanu zomwe muyenera kuchita mukavulala kapena mutakhala ndi malungo kapena matenda. Izi zitha kukhudza shuga m'magazi anu.
  • lankhulani ndi adotolo za zizindikilo za shuga wochuluka komanso wotsika m'magazi komanso zovuta zina za matenda ashuga, zomwe muyenera kuchita mukakhala ndi zizindikilozi, komanso momwe mungapewere izi.

Onetsetsani kuti mukutsatira malangizo onse azakudya ndi masewera olimbitsa thupi omwe adokotala anu adachita.


Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Sitagliptin imatha kubweretsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • modzaza kapena mphuno yothamanga
  • chikhure
  • mutu
  • kutsegula m'mimba
  • nseru

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, siyani kumwa sitagliptin ndikuyimbira dokotala nthawi yomweyo:

  • malungo, nseru, kusanza, kusowa kwa njala, kupweteka kosalekeza komwe kumayambira kumtunda kumanzere kapena pakati pamimba koma kumafalikira kumbuyo
  • kupuma movutikira, kunenepa mwachangu, kapena kutupa kwa mapazi kapena akakolo
  • khungu loyabwa, kuphulika kwa khungu kapena khungu
  • kupweteka pamodzi
  • zidzolo
  • ming'oma
  • kutupa kwa nkhope, milomo, lilime, ndi mmero
  • kuvuta kupuma kapena kumeza

Sitagliptin imatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.


Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amatha kuyitanitsa mayeso ena musanachitike komanso mukamalandira chithandizo cha sitagliptin. Magazi anu a shuga ndi hemoglobin (HbA1c) a glycosylated amayenera kufufuzidwa pafupipafupi kuti mudziwe yankho lanu ku sitagliptin. Dokotala wanu adzakuwuzani momwe mungayang'anire mayankho anu ku sitagliptin poyesa magazi anu kapena mkodzo wamagulu kunyumba. Tsatirani malangizowa mosamala.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

  • Januvia®
  • Janumet® (yokhala ndi Metformin, Sitagliptin)
  • Wachinyamata® (yokhala ndi Simvastatin, Sitagliptin)
  • Masautso® (yokhala ndi Ertugliflozin, Sitagliptin)

Chogulitsa ichi sichikupezeka pamsika. Njira zina zitha kupezeka.

Idasinthidwa Komaliza - 02/15/2021

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