Sorafenib

Zamkati

• Musanatenge sorafenib,
• Sorafenib ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:
• Zizindikiro za bongo zingaphatikizepo izi:

Sorafenib imagwiritsidwa ntchito pochizira renal cell carcinoma (RCC; mtundu wa khansa womwe umayamba mu impso). Sorafenib imagwiritsidwanso ntchito pochizira hepatocellular carcinoma (mtundu wa khansa ya chiwindi) yomwe singachiritsidwe ndi opareshoni komanso mtundu wina wa khansa ya chithokomiro yomwe yafalikira mbali zina za thupi ndipo sangathe kuchiritsidwa ndi ayodini wa radioactive. Sorafenib ali mgulu la mankhwala otchedwa kinase inhibitors. Zimagwira ntchito poletsa proteni yachilendo yomwe imawonetsa kuti ma cell a khansa achulukane. Izi zimathandiza kuletsa kufalikira kwa maselo a khansa.

Sorafenib imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa kawiri patsiku. Sorafenib amatengedwa wopanda chakudya, ola limodzi musanadye kapena maola awiri mutadya. Tengani sorafenib mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani sorafenib ndendende monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi athunthu ndi madzi. Osagawanika, kutafuna, kapena kuwaphwanya.

Dokotala wanu akhoza kuchepetsa mlingo wanu wa sorafenib mukamamwa mankhwala, kapena angakuuzeni kuti musiye kumwa sorafenib kwakanthawi kapena kwanthawi yayitali mukakumana ndi zovuta. Onetsetsani kuti muuze dokotala momwe mukumvera mukamalandira chithandizo ndi sorafenib.

Pitirizani kutenga sorafenib ngakhale mukumva bwino. Osasiya kumwa sorafenib osalankhula ndi dokotala.

Sorafenib sikupezeka m'masitolo. Mutha kungopeza sorafenib kudzera pamakalata kuchokera kuma pharmacy apadera. Funsani dokotala wanu ngati muli ndi mafunso okhudza kulandira mankhwala anu.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge sorafenib,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi mankhwala a sorafenib, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a sorafenib. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu ngati muli ndi khansa yamapapo ndipo mukulandira carboplatin (Paraplatin) ndi paclitaxel (Abraxane, Onxol, Taxol) kapena gemcitabine (Gemzar) ndi cisplatin (Platinol). Dokotala wanu angakuuzeni kuti musatenge sorafenib ngati muli ndi khansa yamapapo ndipo mukulandira mankhwalawa.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala omwe simukulembera, mavitamini, ndi zowonjezera zakudya zomwe mumamwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: mankhwala ena a arrhythmias monga amiodarone (Nexterone, Pacerone), dofetilide (Tikosyn), dronedarone (Multaq), procainamide, quinidine (ku Nuedexta), ndi sotalol (Betapace, Sorine, Sotylize); maanticoagulants (owonda magazi) monga warfarin (Coumadin, Jantoven); carbamazepine (Equetro, Tegretol, Teril); dexamethasone; ibutilide (Corvert); irinotecan (Camptosar); neomycin; phenobarbital; phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); kapena rifampin (Rifadin, Rimactane). Mankhwala ena ambiri amathanso kulumikizana ndi sorafenib, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
• Uzani dokotala wanu ngati mwakhalapo ndi kuthamanga kwa magazi, mavuto a magazi, kupweteka pachifuwa, mavuto amtima, kutalikitsa kwa QT (nyimbo yosasinthasintha yamtima yomwe imatha kukomoka, kutaya chidziwitso, kugwidwa, kapena kufa mwadzidzidzi), potaziyamu, calcium, kapena magnesium m'magazi anu, kugunda kwamtima mosasinthasintha, kulephera kwa mtima, mavuto a impso kupatula khansa ya impso, kapena mavuto a chiwindi kupatula khansa ya chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Muyenera kuyezetsa mimba musanayambe mankhwala. Ngati ndinu mayi amene ali ndi pakati, muyenera kugwiritsa ntchito njira yolerera yoyenerera mukamalandira chithandizo komanso kwa miyezi 6 mutalandira mankhwala. Ngati ndinu wamwamuna wokhala ndi mkazi yemwe angatenge mimba, muyenera kugwiritsa ntchito njira zothandiza kubereka mukamalandira chithandizo komanso kwa miyezi itatu mutalandira mankhwala. Lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Mukakhala ndi pakati mukatenga sorafenib, itanani dokotala wanu mwachangu. Sorafenib atha kuvulaza mwana wosabadwayo.
• auzeni dokotala ngati mukuyamwitsa kapena mukufuna kuyamwitsa. Simuyenera kuyamwa mukamamwa sorafenib komanso kwa masabata awiri mutatha kumwa.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa sorafenib.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Pitani muyezo womwe mwaphonya ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Sorafenib ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutopa
• kufooka
• khungu lofiira
• kutayika tsitsi
• kuyabwa
• khungu louma kapena losenda
• kusowa chilakolako
• kudzimbidwa
• kutsegula m'mimba
• pakamwa pouma
• kuonda
• kupweteka pamodzi
• dzanzi, kupweteka kapena kumva kulira m'manja kapena m'mapazi
• mutu

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

• kuvulaza kapena kutuluka mwachilendo
• wakuda ndi / kapena pobisalira pogona
• magazi ofiira m'mipando
• masanzi amagazi
• kusanza komwe kumawoneka ngati malo a khofi
• malungo
• kupweteka kwambiri m'mimba
• nseru
• kusanza
• kupweteka pachifuwa
• kupuma movutikira
• chizungulire kapena kukomoka
• thukuta kwambiri
• kusala kudya, kugunda, kapena kugunda kwamtima kosazolowereka
• mutu wopweteka mwadzidzidzi
• chisokonezo
• kusintha kwa masomphenya
• kugwidwa
• zidzolo
• kufiira, kupweteka, kutupa kapena matuza padzanja lamanja kapena pansi pa mapazi
• khungu limatuluka komanso khungu
• ming'oma
• kuyabwa
• khungu lofiira
• zilonda mkamwa
• mkodzo wakuda
• chikasu cha khungu kapena maso
• kupweteka kumtunda chakumanja kwam'mimba

Sorafenib ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• kutsegula m'mimba
• zotupa kapena mavuto ena akhungu

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira ku sorafenib. Dokotala wanu amayang'ananso kuthamanga kwa magazi kwanu sabata iliyonse m'milungu isanu ndi umodzi yoyambirira yamankhwala anu ndiyeno nthawi ndi nthawi momwe zingafunikire.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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