Dasatinib

Zamkati

• Musanatenge dasatinib,
• Dasatinib ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:
• Zizindikiro za bongo zingaphatikizepo izi:

Dasatinib imagwiritsidwa ntchito pochiza mtundu wina wamatenda a myeloid leukemia (CML; mtundu wa khansa yamagazi oyera) ngati mankhwala oyamba komanso mwa anthu omwe sangapindule ndi mankhwala ena a leukemia kuphatikiza imatinib (Gleevec) kapena iwo omwe Sangamwe mankhwalawa chifukwa cha zovuta zina. Dasatinib imagwiritsidwanso ntchito pochizira mtundu wina wa CML wosatha mwa ana. Dasatinib imagwiritsidwanso ntchito kuthana ndi mtundu wina wamatenda am'magazi (ALL; mtundu wa khansa yamagazi oyera) mwa anthu omwe sangathenso kupindula ndi mankhwala ena a leukemia kapena omwe sangathe kumwa mankhwalawa chifukwa cha zovuta zina. Dasatinib ali mgulu la mankhwala otchedwa kinase inhibitors. Zimagwira ntchito poletsa proteni yachilendo yomwe imawonetsa kuti ma cell a khansa achulukane. Izi zimathandiza kuletsa kufalikira kwa maselo a khansa.

Dasatinib imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku, m'mawa kapena madzulo, kapena popanda chakudya. Tengani dasatinib mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani dasatinib ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi lonse; osagawana, kutafuna, kapena kuwaphwanya. Valani magolovesi a latex kapena nitrile mukamagwiritsa ntchito mapiritsi omwe aphwanyidwa mwangozi kapena kuthyoka kuti asakhudzidwe ndi mankhwalawo.

Dokotala wanu akhoza kusintha mlingo wanu kapena kuimitsa mankhwala anu a dasatinib kutengera kuyankha kwanu kuchipatala ndi zovuta zina zomwe mungakumane nazo. Lankhulani ndi dokotala wanu za momwe mukumvera mukamalandira chithandizo. Pitirizani kumwa dasatinib ngakhale mutakhala bwino. Osasiya kumwa dasatinib osalankhula ndi dokotala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge dasatinib,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la dasatinib, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a dasatinib. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ena omwe simukupatsidwa, mavitamini, ndi zowonjezera zakudya zomwe mukumwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: anticoagulants ('' opopera magazi '') monga warfarin (Coumadin, Jantoven); mankhwala a anthracycline a khansa monga daunorubicin (Cerubidine), doxorubicin (Doxil), ndi epirubicin (Ellence); ma antifungal ena monga ketoconazole (Nizoral), itraconazole (Onmel, Sporanox), ndi voriconazole (Vfend); clarithromycin (Biaxin, mu PrevPac); dexamethasone; mankhwala ena omwe amachiza kachilombo ka HIV monga HIV (monga atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), ndi saquinavir (Invirase); mankhwala ena osagunda pamtima monga amiodarone (Nexterone, Pacerone), disopyramide (Norpace), dofetilide (Tikosyn), flecainide (Tambocor), mexiletine (Mexitil), procainamide, propafenone (Rythmol), quinidine (ku Nuedexta), Betapace, Betapace AF, Sorine), mankhwala ochepetsa asidi m'mimba monga cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), ranitidine (Zantac), esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), ndi rabeprazole (AcipHex); nefazodone; rifampin (Rimactane, Rifadin, ku Rifater, ku Rifamate); ndi telithromycin (Ketek); Mankhwala ena ambiri amathanso kulumikizana ndi dasatinib, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• ngati mukumwa maantacid, monga aluminium hydroxide / magnesium hydroxide (Maalox), calcium carbonate (Tums), kapena calcium carbonate ndi magnesium (Rolaids), tengani maola awiri musanadye kapena maola awiri mutatenga dasatinib.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
• Uzani dokotala wanu ngati mwakhalapo ndi vuto la kusagwirizana ndi lactose (kulephera kugaya mkaka), potaziyamu kapena magnesium m'magazi anu, matenda a QT (mtima womwe ungayambitse chizungulire, kukomoka, kapena kugunda kwamtima), mavuto ndi chitetezo cha mthupi lanu, kapena chiwindi, mapapo, kapena matenda amtima.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Simuyenera kutenga pakati mukamamwa dasatinib komanso masiku 30 mutatha kumwa. Lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Mukakhala ndi pakati mukatenga dasatinib, itanani dokotala wanu. Amayi omwe ali ndi pakati sayenera kunyamula mapiritsi a dasatinib osweka kapena osweka. Dasatinib itha kuvulaza mwana wosabadwayo.
• osamwa mkaka mukamwa dasatinib komanso kwa masabata awiri mutatha kumwa.
• Muyenera kudziwa kuti mankhwalawa amachepetsa kubereka kwa abambo ndi amai. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito dasatinib.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa dasatinib.

Musadye zipatso zamphesa kapena kumwa madzi amphesa mukamamwa mankhwalawa.

Pitani muyezo womwe mwaphonya ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Dasatinib ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kupweteka kwa minofu
• kufooka
• kupweteka pamodzi
• kupweteka, kutentha kapena kumva kulasalasa m'manja kapena m'mapazi
• zidzolo
• khungu lofiira
• khungu losenda
• kutupa, kufiira, ndi kupweteka mkamwa
• zilonda mkamwa
• kutsegula m'mimba
• nseru
• kusanza
• kudzimbidwa
• kupweteka m'mimba kapena kutupa
• kusowa chilakolako
• kuonda

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• malungo, zilonda zapakhosi, kuzizira, ndi / kapena zizindikiro zina za matenda
• kutupa kwa maso, manja, mikono, mapazi, akakolo, kapena miyendo yakumunsi
• kunenepa mwadzidzidzi
• kuvuta kupuma, makamaka pogona
• kukhosomola ntchofu zapinki kapena zamagazi
• chifuwa chowuma
• kupweteka pachifuwa komwe kumakulirakulira mukakhosomola, kupopera, kapena kupuma kwambiri
• kuthamanga pachifuwa
• chizungulire
• kukomoka
• kugunda kwamtima msanga, kosasinthasintha, kapena kwamphamvu
• mutu
• kutopa
• chisokonezo
• kukulitsa kwa m'mawere kwakanthawi (mwa ana)
• kuvulaza kapena kutuluka mwachilendo
• mipando yakuda ndi yodikira
• magazi ofiira m'mipando
• masanzi amagazi
• kusanza komwe kumawoneka ngati malo a khofi
• mawu odekha kapena ovuta
• kufooka kapena kufooka kwa mkono kapena mwendo

Dasatinib ingayambitse kuchepa kapena kupweteka kwa mafupa kwa ana. Dokotala wa mwana wanu amayang'anira kukula kwa mwana wanu mosamala pamene akutenga dasatinib. Lankhulani ndi dokotala wanu za kuopsa kopatsa mankhwalawa kwa mwana wanu.

Dasatinib ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• kuvulaza kapena kutuluka mwachilendo
• malungo, zilonda zapakhosi, kuzizira, ndi / kapena zizindikiro zina za matenda
• kupuma movutikira
• kugunda kwamtima mwachangu
• mutu
• khungu lotumbululuka
• chisokonezo
• kutopa

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu musanachitike komanso mukamalandira chithandizo kuti muwone momwe thupi lanu likuyankhira ku dasatinib.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Zosakaniza^®