Jekeseni wa Golimumab

Zamkati

• Jekeseni wa Golimumab (Simponi) amagwiritsidwa ntchito kuthana ndi zovuta zina zamatenda amthupi (momwe chitetezo cha mthupi chimagwirira mbali zabwino za thupi ndikupangitsa kupweteka, kutupa, ndi kuwonongeka) kuphatikiza:
• Jekeseni wa Golimumab (Simponi Aria) imagwiritsidwanso ntchito kuthana ndi zovuta zamatenda ena monga:
• Musanagwiritse ntchito jakisoni wa golimumab,
• Jekeseni wa Golimumab imatha kuyambitsa zovuta. Uzani dokotala wanu ngati chimodzi mwazizindikirozi ndi zoopsa kapena sichitha:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

Kugwiritsa ntchito jakisoni wa golimumab kumachepetsa kuthekera kwanu kothana ndi matenda ndikuchulukitsa chiopsezo choti mutenga matenda akulu, kuphatikiza matenda owopsa a fungal, bakiteriya, kapena ma virus omwe amafalikira m'thupi. Matendawa angafunike kuthandizidwa kuchipatala ndipo atha kupha. Uzani dokotala wanu ngati nthawi zambiri mumakhala ndi matenda aliwonse kapena ngati mukuganiza kuti mutha kukhala ndi matenda aliwonse pano. Izi zimaphatikizapo matenda ang'onoang'ono (monga mabala otseguka kapena zilonda), matenda omwe amabwera ndikadutsa (monga zilonda zozizira) ndi matenda opatsirana omwe samatha. Muuzeni adotolo ngati mwadwalapo kapena munakhalapo ndi matenda ashuga, kachilombo ka HIV, kachilombo ka HIV, kapenanso vuto lina lililonse lomwe limakhudza chitetezo chamthupi. Muyeneranso kuuza adotolo ngati mukukhala kapena mudakhalako m'malo monga zigwa za Ohio kapena Mississippi komwe matenda ofala a fungus amapezeka kwambiri. Funsani dokotala wanu ngati simukudziwa ngati matendawa ndiofala m'dera lanu. Uzani dokotala ngati mukumwa mankhwala omwe amachepetsa chitetezo chamthupi monga awa: abatacept (Orencia); anakinra (Kineret); methotrexate (Rheumatrex); rituximab (Rituxan); steroids kuphatikizapo dexamethasone, methylprednisolone (Medrol), prednisolone (Prelone) ndi prednisone; tocilizumab (Actemra); ndi ma TNF-blockers ena monga adalimumab (Humira), certolizumab (Cimzia), etanercept (Enbrel), ndi infliximab (Remicade).

Dokotala wanu adzakuyang'anirani ngati muli ndi matendawa mukamalandira chithandizo chake. Ngati muli ndi zizindikiro zotsatirazi musanayambe kumwa mankhwala kapena ngati mukukumana ndi zizindikiro zotsatirazi mukamalandira chithandizo kapena mutangochoka kumene, pitani kuchipatala nthawi yomweyo: kufooka; thukuta; chikhure; chifuwa; kutsokomola ntchofu zamagazi; malungo; kuonda; kutopa kwambiri; kutsegula m'mimba; kupweteka m'mimba; khungu lofunda, lofiira, kapena lopweteka; zilonda pakhungu; kupweteka kovuta, kovuta, kapena pafupipafupi; kapena zizindikiro zina za matenda.

Mutha kukhala ndi chifuwa chachikulu (TB, mtundu wamatenda am'mapapo) kapena hepatitis B (mtundu wa matenda a chiwindi) koma mulibe zisonyezo za matendawa. Poterepa, jakisoni wa golimumab akhoza kuonjezera chiopsezo kuti matenda anu adzakula kwambiri ndipo mudzakhala ndi zizindikilo. Dokotala wanu adzakuyesani khungu kuti muwone ngati muli ndi kachilombo ka TB kosagwira ntchito ndipo atha kuyitanitsa kuyesa magazi kuti muwone ngati muli ndi matenda a hepatitis B. Ngati ndi kotheka, dokotala wanu adzakupatsani mankhwala ochizira matendawa musanayambe kugwiritsa ntchito jakisoni wa golimumab. Uzani dokotala wanu ngati mwakhalapo ndi TB kapena hepatitis B, ngati mudapitako kudziko lililonse kumene TB imafala, kapena ngati mwakhalapo ndi munthu amene ali ndi TB. Ngati muli ndi zizindikiro zotsatirazi za chifuwa chachikulu cha TB, kapena ngati muli ndi zina mwazizindikiro mukumwa mankhwala, pitani kuchipatala mwachangu: chifuwa, kuonda, kuchepa kwa minofu, kapena malungo. Komanso itanani dokotala wanu nthawi yomweyo ngati muli ndi zina mwazizindikiro za matenda a chiwindi a B kapena ngati muli ndi zina mwazizindikiro mukalandira kapena mutalandira chithandizo: kutopa kwambiri, khungu lachikaso kapena maso, kusowa chilakolako chambiri, nseru kapena kusanza, kupweteka kwa minofu, mkodzo wamdima, matumbo ofiira dongo, malungo, kuzizira, kupweteka m'mimba, kapena zotupa.

Ana ena, achinyamata, komanso achikulire omwe adalandira jakisoni ya golimumab ndi mankhwala ofanana nawo adayamba khansa yowopsa kapena yowopsa pamoyo kuphatikizapo lymphoma (khansa yomwe imayamba m'maselo omwe amalimbana ndi matenda). Achinyamata ena achikulire ndi anyamata omwe adatenga golimumab kapena mankhwala ofanana nawo adayamba ndi hepatosplenic T-cell lymphoma (HSTCL), khansa yoopsa kwambiri yomwe imayambitsa imfa m'kanthawi kochepa. Ambiri mwa anthu omwe adapanga HSTCL anali kuchiritsidwa ndi matenda a Crohn (matenda omwe thupi limagwiritsa ntchito gawo la m'mimba, kumayambitsa kupweteka, kutsegula m'mimba, kuchepa thupi, ndi malungo) kapena ulcerative colitis (vuto lomwe limayambitsa kutupa ndi zilonda. m'mbali mwa kholingo [matumbo akulu] ndi thumbo) wokhala ndi golimumab kapena mankhwala ofanana nawo pamodzi ndi mankhwala ena otchedwa azathioprine (Imuran) kapena 6-mercaptopurine (Purinethol). Ana ndi achinyamata sayenera kulandira jakisoni wa golimumab, koma nthawi zina, dokotala amatha kusankha kuti jakisoni wa golimumab ndiye mankhwala abwino kwambiri ochizira matenda a mwana. Ngati jekeseni ya golimumab imaperekedwa kwa mwana wanu, muyenera kulankhula ndi dokotala wa mwana wanu za kuopsa ndi phindu logwiritsa ntchito mankhwalawa. Mwana wanu akayamba kudwala matendawa, itanani dokotala wake mwachangu: kuonda kosadziwika; zotupa zotupa pakhosi, pansi, kapena kubuula; kapena kuvulaza kosavuta kapena kutuluka magazi.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba chithandizo ndi jakisoni wa golimumab ndipo nthawi iliyonse mukadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm)kapena tsamba laopanga kuti mupeze Medication Guide.

Lankhulani ndi dokotala wanu za kuopsa kolandila jakisoni wa golimumab.

Jekeseni wa Golimumab (Simponi) amagwiritsidwa ntchito kuthana ndi zovuta zina zamatenda amthupi (momwe chitetezo cha mthupi chimagwirira mbali zabwino za thupi ndikupangitsa kupweteka, kutupa, ndi kuwonongeka) kuphatikiza:

• nyamakazi ya nyamakazi (momwe thupi limagwirira ntchito ziwalo zake zomwe zimayambitsa kupweteka, kutupa, ndi kutayika kwa ntchito) pamodzi ndi methotrexate (Otrexup, Rasuvo, Trexall) mwa akulu,
• ankylosing spondylitis (momwe thupi limagwirira malo olumikizana ndi msana ndi madera ena omwe amayambitsa kupweteka komanso kuwonongeka kwamagulu) mwa akulu,
• psoriatic nyamakazi (vuto lomwe limayambitsa kupweteka kwamagulu ndi kutupa ndi masikelo pakhungu) lokha kapena kuphatikiza methotrexate mwa akulu, ndi
• ulcerative colitis (vuto lomwe limayambitsa kutupa ndi zilonda mkatikati mwa matumbo [matumbo akulu] ndi rectum) pomwe mankhwala ena ndi chithandizo sichidathandize kapena sichingaloledwe.

Jekeseni wa Golimumab (Simponi Aria) imagwiritsidwanso ntchito kuthana ndi zovuta zamatenda ena monga:

• nyamakazi ya nyamakazi (momwe thupi limagwirira ntchito ziwalo zake zomwe zimayambitsa kupweteka, kutupa, ndi kutayika kwa ntchito) pamodzi ndi methotrexate (Otrexup, Rasuvo, Trexall) mwa akulu,
• ankylosing spondylitis (momwe thupi limagwirira malo olumikizana ndi msana ndi madera ena omwe amayambitsa kupweteka komanso kuwonongeka kwamagulu) mwa akulu,
• psoriatic nyamakazi (vuto lomwe limayambitsa kupweteka kwamagulu ndi kutupa ndi masikelo pakhungu) mwa akulu ndi ana azaka 2 kapena kupitirira,
• polyarticular juvenile idiopathic arthritis (PJIA; mtundu wamatenda amwana omwe amakhudza ziwalo zisanu kapena kupitilira apo m'miyezi isanu ndi umodzi yoyambirira ya vutoli, zomwe zimapweteka, kutupa, komanso kutha kwa ntchito) mwa ana azaka 2 kapena kupitilira apo.

Golimumab ali mgulu la mankhwala otchedwa tumor necrosis factor (TNF) inhibitors. Zimagwira ntchito poletsa zochita za TNF, chinthu m'thupi chomwe chimayambitsa kutupa.

Jakisoni wa Golimumab umabwera ngati yankho (madzi) kuti alowetse subcutaneous (pansi pa khungu) kapena kudzera m'mitsempha (mumtsempha). Pamene golimumab imaperekedwa modzidzimutsa kuti ichiritse nyamakazi, psoriatic nyamakazi, kapena ankylosing spondylitis, imaperekedwa kamodzi pamwezi. Pamene golimumab imaperekedwa mozungulira kuti ichiritse ulcerative colitis, nthawi zambiri imaperekedwa kamodzi sabata iliyonse pamlingo woyamba woyamba (sabata 0 ndi sabata 2) ndiyeno kamodzi pamasabata anayi pambuyo pake. Pamene golimumab imaperekedwa mwachangu ndi dokotala kapena namwino m'malo azisamaliro kuti athe kuchiza nyamakazi, ankylosing spondylitis. psoriatic arthritis, kapena polyarticular juvenile idiopathic arthritis, nthawi zambiri imaperekedwa kwa mphindi 30 kamodzi sabata iliyonse pamlingo woyamba woyamba (sabata 0 ndi sabata 2) ndiyeno kamodzi pamasabata 4 pambuyo pake. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Gwiritsani ntchito jakisoni wa golimumab monga momwe mwalangizira. Osabaya jakisoni wochulukirapo kapena kumubaya nthawi zambiri kuposa momwe adanenera.

Mulandila jakisoni wanu woyamba wocheperako wa jakisoni wa golimumab muofesi ya dokotala wanu. Pambuyo pake, dokotala wanu angakulolezeni kuti muyese jekeseni wa golimumab nokha kapena kuti mnzanu kapena wachibale azibaya jakisoni. Musanagwiritse ntchito jekeseni wa golimumab nokha nthawi yoyamba, werengani malangizo olembedwa omwe amabwera nawo. Funsani dokotala wanu kapena wamankhwala kuti akuwonetseni kapena munthu yemwe ati adzalandire mankhwalawo momwe angabayire.

Jekeseni wa Golimumab (Simponi) amabwera mu ma syringe oyikiratu komanso zida zopangira jakisoni wa jakisoni wamagetsi. Gwiritsani ntchito sirinji iliyonse kapena kachipangizo kamodzi ndipo jekeseni yankho mu syringe kapena chipangizocho. Ngakhale mutakhalabe ndi yankho mu syringe kapena cholembera mutabaya, musabayenso. Tayani masirinji ndi zida zogwiritsidwa ntchito muchidebe chosagundika. Lankhulani ndi dokotala wanu kapena wamankhwala za momwe mungatayire chidebe chosagwira mankhwala.

Chotsani jakisoni woyikiratu kapena mafuta oyikiratu m'firiji ndikuwalola kuti azitha kutentha kwa mphindi 30 musanagwiritse ntchito. Chotsani m'katoni mwake, ndipo mulole kuti apumule pamalo athyathyathya kuti azitha kutentha. Osayesa kutenthetsa mankhwalawo powotenthetsa mu microwave, ndikuwayika m'madzi otentha, kapena njira ina iliyonse.

Musachotse kapu pachipangizo chodzipangira nokha kapena chivundikiro kuchokera mu syringe yoyikiratu pomwe mankhwala akutentha. Muyenera kuchotsa kapu kapena kuphimba osapitilira mphindi zisanu musanabaye mankhwala. Musasinthe kapu kapena chivundikiro mukachichotsa. Musagwiritse ntchito jakisoni kapena chipangizo ngati mutachigwetsera pansi chimakhala chotseguka kapena chosavundikira.

Musagwedeze chipangizo chodzipangira kapena jakisoni woyikiratu. Izi zitha kuwononga mankhwala.

Nthawi zonse yang'anani jekeseni wa golimumab musanaibayize. Onani tsiku lothera ntchito lomwe lidasindikizidwa pachipangizo cha jakisoni kapena katoni ndipo musagwiritse ntchito mankhwalawa ngati tsiku lomaliza latha. Musagwiritse ntchito syringe kapena chida chodzipangira nokha chomwe chimawoneka kuti chasokonekera, ndipo musagwiritse ntchito chida chodzipangira ngati chitetezo chadulidwa. Yang'anani pazenera lowonera pa syringe kapena chida chojambulira. Madzi amkati ayenera kukhala oyera komanso opanda utoto kapena achikaso pang'ono, koma atha kukhala ndi tinthu tating'onoting'ono toyera kapena kuwira kwa mpweya. Musagwiritse ntchito syringe kapena chida ngati mankhwalawo ali ndi mitambo kapena ataphimbidwa kapena ali ndi tinthu tating'ono.

Malo abwino kwambiri ojambulira golimumab ndi kutsogolo kwa ntchafu zapakati. Komabe, mutha kulanso jekeseni wa golimumab m'mimba mwanu pansi pamchombo wanu, kupatula malo a mainchesi awiri (5 sentimita) mozungulira mchombo. Ngati wina akukupatsani jakisoni, munthu ameneyo amathanso kubaya mankhwalawo m'manja mwanu. Sankhani malo osiyana kuti mubayire mankhwala tsiku lililonse. Osalowetsa malo omwe khungu lanu ndi lofiira, lophwanyika, lofewa, lolimba kapena lansalu, kapena komwe muli ndi zipsera kapena zotambalala.

Jakisoni wa Golimumab atha kuthandizira kuwongolera matenda anu koma sangachiritse. Pitirizani kugwiritsa ntchito jakisoni wa golimumab ngakhale mukumva bwino. Osasiya kugwiritsa ntchito jakisoni wa golimumab osalankhula ndi dokotala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanagwiritse ntchito jakisoni wa golimumab,

• uzani dokotala wanu komanso wamankhwala ngati mukugwirizana ndi jakisoni wa golimumab, mankhwala ena aliwonse, kapena zosakaniza zilizonse za jakisoni ya golimumab. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza. Uzaninso dokotala wanu ngati inu kapena munthu amene angakuthandizeni kubaya jakisoni wa golimumab ali ndi vuto la latex kapena labala.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchula mankhwala omwe atchulidwa mgulu la CHENJEZO LACHENJEZO ndi mankhwala aliwonse awa: maanticoagulants ('magazi opopera magazi') monga warfarin (Coumadin), cyclosporine (Gengraf, Neoral, Sandimmune), ndi theophylline (Theochron, Theolair, Uniphyl ). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• Uzani dokotala wanu ngati mwakhalapo ndi khansa, psoriasis (matenda apakhungu momwe zigamba zofiira zimakhalira pakhungu), vuto lililonse lomwe limakhudza dongosolo lanu lamanjenje monga multiple sclerosis (MS, matenda omwe misempha simachita Zimagwira bwino kuyambitsa kufooka, dzanzi, kuchepa kwa kulumikizana kwa minofu ndi mavuto m'masomphenya, kuyankhula, ndi kuwongolera chikhodzodzo) kapena matenda a Guillain Barre (kufooka, kugwedezeka, komanso ziwalo zotheka chifukwa cha kuwonongeka kwamitsempha mwadzidzidzi), nambala yotsika yamtundu uliwonse wamaselo amwazi , kapena matenda amtima.
• uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa.Mukakhala ndi pakati mukamagwiritsa ntchito jakisoni wa golimumab, itanani dokotala wanu. Ngati mumagwiritsa ntchito jakisoni wa golimumab mukakhala ndi pakati, onetsetsani kuti mwalankhula ndi dokotala wa mwana wanu izi zitabadwa. Mwana wanu angafunikire kulandira katemera wina mochedwa kuposa nthawi zonse.
• mulibe katemera popanda kulankhula ndi dokotala.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Jekeseni mlingo womwe mwaphonya mukangokumbukira, ndikubaya jekeseni wanu wotsatira panthawi yokhazikika. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Osabaya jakisoni kawiri kuti mupange yomwe mwaphonya. Itanani dokotala wanu kapena wamankhwala ngati simukudziwa nthawi yoyenera jekeseni wa golimumab.

Jekeseni wa Golimumab imatha kuyambitsa zovuta. Uzani dokotala wanu ngati chimodzi mwazizindikirozi ndi zoopsa kapena sichitha:

• kufiira, kuyabwa, kufinya, kupweteka, kapena kutupa pamalo pomwe jekeseni ya jakisoni idabayidwa
• chizungulire

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

• kupweteka pachifuwa
• kupuma movutikira
• kutupa kwa akakolo kapena miyendo yakumunsi
• masomphenya amasintha
• kufooka, dzanzi, kapena kumva kulira kwa mikono kapena miyendo
• zigamba zofiira kapena mabampu odzaza mafinya pakhungu
• matuza
• kupweteka kumtunda chakumanja kwam'mimba
• kuvulaza kosavuta kapena kutuluka magazi
• khungu lotumbululuka
• zidzolo pamasaya kapena gawo lina la thupi
• kumvetsetsa dzuwa
• kupweteka pamodzi
• ming'oma
• kutupa kwa maso, nkhope, milomo, lilime, pakamwa, kapena pakhosi
• kuvuta kupuma kapena kumeza

Jakisoni wa Golimumab ungapangitse kuti pakhale chiopsezo chotenga khansa ya khansa yapakhungu (mtundu wa khansa yapakhungu), lymphoma (khansa yomwe imayamba m'maselo omwe amalimbana ndi matenda), leukemia (khansa yomwe imayamba m'maselo oyera amwazi), ndi mitundu ina ya khansa kuposa anthu omwe musalandire mankhwala. Lankhulani ndi dokotala wanu za kuopsa kolandila jakisoni wa golimumab.

Jekeseni wa Golimumab imatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Sungani mu firiji koma osazizira. Sungani mankhwalawo mu katoni yoyambirira kuti muteteze ku kuwala.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Musalole kuti wina aliyense agwiritse ntchito mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Simponi^®
• Simponi^® Aria