Jekeseni wa Temozolomide
Zamkati
- Musanalandire temozolomide,
- Temozolomide itha kubweretsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
- Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:
- Zizindikiro za bongo zingaphatikizepo izi:
Temozolomide imagwiritsidwa ntchito pochizira mitundu ina ya zotupa zamaubongo. Temozolomide ali mgulu la mankhwala otchedwa alkylating agents. Zimagwira pochepetsa kapena kuletsa kukula kwa maselo a khansa mthupi lanu.
Jakisoni wa Temozolomide amabwera ngati ufa woti uwonjezedwe pamadzimadzi ndikubayidwa mphindi 90 mkati mwa mtsempha (ndi mtsempha) ndi dokotala kapena namwino. Nthawi zambiri amabayidwa kamodzi patsiku. Kwa mitundu ina ya zotupa zamaubongo, temozolomide imaperekedwa tsiku lililonse kwa masiku 42 mpaka 49. Kenako, mutapuma masiku 28, atha kuperekedwa kamodzi patsiku kwa masiku 5 motsatizana, kutsatiridwa ndi masiku 23 musanabwereze muyeso wotsatira wotsatira. Pochiza mitundu ina ya zotupa zamaubongo, temozolomide imaperekedwa kamodzi patsiku kwa masiku 5 motsatizana, ndikutsatira masiku 23 musanabwereze muyeso wotsatira wotsatira. Kutalika kwa chithandizo kumadalira momwe thupi lanu limayankhira ndi mtundu wa khansa yomwe muli nayo.
Dokotala wanu angafunike kuchedwetsa chithandizo chanu kapena kusintha mlingo wanu malingana ndi momwe mungayankhire ndi zomwe mungakumane nazo. Lankhulani ndi dokotala wanu za momwe mukumvera mukamalandira chithandizo cha temozolomide.
Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.
Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.
Musanalandire temozolomide,
- uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi temozolomide, dacarbazine (DTIC-Dome) mankhwala ena aliwonse, kapena china chilichonse mu jakisoni wa temozolomide. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
- auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: carbamazepine (Carbatrol, Epitol, Tegretol); co-trimoxazole (Bactrim, Septra); phenytoin (Dilantin, Phenytek); steroids monga dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), ndi prednisone (Deltasone); ndi valproic acid (Stavzor, Depakene).
- uzani dokotala wanu ngati mwakhalapo ndi matenda a impso kapena chiwindi.
- muyenera kudziwa kuti temozolomide itha kusokoneza kupanga umuna mwa amuna. Komabe, simuyenera kuganiza kuti simungapatse wina mimba. Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati, kapena ngati mukufuna kukhala ndi mwana. Inu kapena mnzanu simuyenera kutenga pakati pomwe mukulandira temozolomide. Gwiritsani ntchito njira yodalirika yolerera popewa kutenga pakati. Mukakhala ndi pakati mukalandira temozolomide, itanani dokotala wanu. Temozolomide itha kuvulaza mwana wosabadwayo.
- uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwa mukalandira temozolomide.
Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.
Temozolomide itha kubweretsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
- nseru
- kusanza
- kutsegula m'mimba
- kudzimbidwa
- kusowa chilakolako
- zilonda mkamwa ndi pakhosi
- mutu
- khungu lotumbululuka
- kusowa mphamvu
- kutayika bwino kapena kulumikizana
- kukomoka
- chizungulire
- kutayika tsitsi
- kusowa tulo
- mavuto okumbukira
- kupweteka, kuyabwa, kutupa, kapena kufiira pamalo pomwe adalowetsedwa mankhwala
- kusintha kwa masomphenya
Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:
- kutuluka mwachilendo kapena kuphwanya
- ofiira kapena akuda, mipando yodikira
- pinki, wofiira, kapena mkodzo wakuda
- kutsokomola kapena kusanza magazi kapena zinthu zomwe zimawoneka ngati malo a khofi
- malungo, zilonda zapakhosi, kutsokomola kosalekeza komanso kuchulukana, kapena zizindikilo zina za matenda
- kutopa kapena kufooka kosazolowereka
- zidzolo
- osakhoza kusuntha mbali imodzi ya thupi
- kupuma movutikira
- kugwidwa
- chikasu cha khungu kapena maso
- kupweteka kumtunda chakumanja kwam'mimba
- kuchepa pokodza
Temozolomide imatha kuonjezera chiopsezo kuti mudzadwala khansa ina. Lankhulani ndi dokotala wanu za kuopsa kotenga temozolomide.
Temozolomide imatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.
Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).
Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.
Zizindikiro za bongo zingaphatikizepo izi:
- kutuluka mwachilendo kapena kuphwanya
- ofiira kapena akuda, mipando yodikira
- pinki, wofiira, kapena mkodzo wakuda
- kutsokomola kapena kusanza magazi kapena zinthu zomwe zimawoneka ngati malo a khofi
- malungo, zilonda zapakhosi, kutsokomola kosalekeza komanso kuchulukana, kapena zizindikilo zina za matenda
Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu adzaitanitsa mayeso a labotale musanapite, mkati, komanso mutalandira chithandizo chanu kuti muwone momwe thupi lanu likuyankhira komanso kuti temozolomide awone ngati ma cell amwazi wanu akukhudzidwa ndi mankhwalawa.
Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.
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