Naloxegol

Zamkati

• Musanatenge naloxegol,
• Naloxegol ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Mukakumana ndi chizindikirochi, siyani kumwa naloxegol ndikuimbira dokotala nthawi yomweyo:
• Zizindikiro za bongo zingaphatikizepo izi:

Naloxegol amagwiritsidwa ntchito pochiza kudzimbidwa chifukwa cha opiate (chomwa mankhwalawa) mankhwala opweteka kwa akulu omwe ali ndi zowawa (zopitilira) zomwe sizimayambitsa khansa. Naloxegol ali mgulu la mankhwala otchedwa peripherally acting mu-opioid receptor antagonists. Zimagwira ntchito poteteza matumbo ku zotsatira za mankhwala opiate (narcotic).

Naloxegol amabwera ngati piritsi kuti atenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku, osachepera ola limodzi isanakwane kapena maola awiri mutangodya tsiku loyamba. Tengani naloxegol mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani naloxegol ndendende monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Ngati mukulephera kumeza mapiritsi athunthu, phwanyani piritsi kukhala ufa ndikusakanikirana ndi galasi lokhala ndi ma ounces 120 a madzi. Imwani chisakanizo nthawi yomweyo. Kenako, dzazani galasi ndi madzi okwana ma ml. 120, sungani zomwe zili mkatimo, ndikumwa zina zotsalazo.

Ngati muli ndi chubu cha nasogastric (NG), dokotala wanu kapena wamankhwala akufotokozerani momwe mungakonzekerere mapiritsi a naloxegol kuti apereke kudzera mu chubu la NG.

Muyenera kusiya kumwa mankhwala ena ofewetsa ululu musanayambe kumwa naloxegol. Onetsetsani kuti dokotala wanu adziwe ngati naloxegol sikukuthandizani mutatha kumwa masiku atatu. Dokotala wanu angakuuzeni kuti mumwe mankhwala ena amadzimadzi otsekemera.

Uzani dokotala wanu ngati mwasiya kumwa mankhwala opiate (narcotic). Dokotala wanu angakuuzeni kuti musiye kumwa naloxegol.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge naloxegol,

• uzani dokotala wanu komanso wamankhwala kuti ngati muli ndi vuto la naloxegol, mankhwala ena aliwonse, kapena chilichonse mwapiritsi a naloxegol. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• Uzani dokotala wanu ngati mukumwa clarithromycin (Biaxin), itraconazole (Onmel, Sporanox), kapena ketoconazole (Nizoral). Dokotala wanu angakuuzeni kuti musatenge naloxegol ngati mukumwa mankhwala amodzi kapena angapo.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mumamwa kapena mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: carbamazepine (Tegretol); diltiazem (Cardizem, Dilacor, Tiazac); efavirenz (ku Atripla, Sustiva); erythromycin (EES, E-Mycin, Erythrocin); methadone (Dolophine, Methadose); Otsutsana ndi opiate ena monga methylnaltrexone (Relistor), naloxone (Evzio, ku Bunavail, ku Suboxone, ku Zubsolv), kapena naltrexone (Revia, ku Contrave, ku Embeda, Vivitrol); rifampin (Rifadin, mu Rifamate, Rifater, Rimactane); kapena verapamil (Calan, Covera, Verelan). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi naloxegol, chifukwa chake onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka St. John's Wort.
• uzani dokotala wanu ngati mwakhalapo ndi zotsekeka m'matumbo (kutsekeka m'matumbo mwanu). Dokotala wanu angakuuzeni kuti musatenge naloxegol.
• Uzani dokotala wanu ngati mwakhalapo ndi vuto la m'mimba kapena matumbo monga zilonda zam'mimba (zilonda zamkati mwa m'mimba), matenda a Crohn's (momwe thupi limagwirira ntchito m'mimba, kumayambitsa kupweteka, kutsegula m'mimba, kuchepa thupi, ndi malungo), diverticulitis (zotupa zotupa mkati mwa matumbo akulu), khansa ya m'mimba kapena matumbo, kapena matenda a Ogilvie (vuto lomwe limatuluka m'matumbo); kapena matenda a impso kapena chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga naloxegol, itanani dokotala wanu.

Musadye zipatso zamphesa kapena kumwa madzi amphesa mukamamwa mankhwalawa.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Naloxegol ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutsegula m'mimba
• nseru
• mpweya
• kupweteka m'mimba
• kusanza
• mutu
• thukuta
• kuzizira
• nkhawa
• kupsa mtima
• kuyasamula

Zotsatira zina zoyipa zingakhale zazikulu. Mukakumana ndi chizindikirochi, siyani kumwa naloxegol ndikuimbira dokotala nthawi yomweyo:

• kupweteka kwambiri m'mimba ndi m'mimba
• zidzolo; ming'oma; kutupa kwa nkhope, milomo, mmero, lilime, manja, kapena mapazi

Naloxegol imatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• kupweteka m'mimba
• kutsegula m'mimba
• nseru
• kuzizira
• mphuno
• thukuta

Sungani maimidwe onse ndi dokotala wanu.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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