Isavuconazonium

Zamkati

• Musanatenge isavuconazonium,
• Isavuconazonium ikhoza kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:
• Zizindikiro za bongo zingaphatikizepo izi:

Isavuconazonium amagwiritsidwa ntchito pochiza matenda opatsirana a fungal monga aspergillosis (matenda opatsirana omwe amayamba m'mapapu ndikufalikira kudzera m'magazi kupita ku ziwalo zina) ndi mucormycosis (matenda opatsirana omwe nthawi zambiri amayamba mumachimo, ubongo, kapena mapapo). Isavuconazonium ali mgulu la mankhwala otchedwa azole antifungals. Zimagwira ntchito pochepetsa kukula kwa bowa komwe kumayambitsa matenda.

Isavuconazonium imabwera ngati kapisozi kuti itenge pakamwa. Nthawi zambiri amatengedwa wopanda chakudya maola 8 aliwonse pamlingo woyambirira asanu ndi limodzi kenako kamodzi patsiku. Tengani isavuconazonium mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani isavuconazonium ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza makapisozi lonse; osatsegula, kutafuna, kusungunula, kapena kuwaphwanya.

Kutalika kwa chithandizo chanu kumadalira thanzi lanu lonse, mtundu wa matenda omwe muli nawo, komanso momwe mumayankhira mankhwalawo. Pitirizani kumwa isavuconazonium ngakhale mutakhala bwino. Osasiya kumwa isavuconazonium osalankhula ndi dokotala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge isavuconazonium,

• auzeni adotolo ndi azachipatala ngati muli ndi matupi awo sagwirizana ndi isavuconazonium, fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole, mankhwala ena aliwonse, kapena zosakaniza zilizonse mu makapisozi a isavuconazonium. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• uzani dokotala ngati mukumwa carbamazepine (Carbatrol, Tegretol), ketoconazole (Nizoral), phenobarbital, rifampin (Rifadin, Rifamate), ritonavir (Norvir, ku Kaletra), kapena wort wa St. Dokotala wanu angakuuzeni kuti musamwe isavuconazonium ngati mukumwa mankhwala amodzi kapena angapo.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: atorvastatin (Lipitor), bupropion (Aplenzin, Forfivo XL, Wellbutrin, Zyban), cyclosporine (Gengraf, Neoral, Sandimmune), digoxin (Digitek, Lanoxicaps, Lanoxin), midazolam, mycophenolate mofetil (CellCept ), sirolimus (Rapamune), kapena tacrolimus (Prograf). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi isavuconazonium, chifukwa chake onetsetsani kuti mumauza dokotala za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• auzeni adotolo ngati inu kapena wina aliyense m'banja mwanu adakhalapo kapena adakhalapo ndi vuto lalifupi la QT (zomwe zimawonjezera chiwopsezo cha kugunda kwamtima, chizungulire, kukomoka, kapena kufa mwadzidzidzi). Dokotala wanu angakuuzeni kuti musatenge isavuconazonium.
• Uzani dokotala wanu ngati mwakhalapo ndi vuto la mtima kapena chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga isavuconazonium, itanani dokotala wanu.

Lankhulani ndi dokotala wanu za kudya mphesa ndi kumwa madzi amphesa mukamamwa mankhwalawa.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Isavuconazonium ikhoza kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutsegula m'mimba
• kudzimbidwa
• mutu
• kupweteka kwa msana
• chifuwa
• kuvuta kugona kapena kugona
• nkhawa
• kubvutika
• chisokonezo
• kuchepa kudya

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• ming'oma
• zidzolo
• kuyabwa
• khungu losenda kapena lotupa
• nseru
• kusanza
• chikasu cha khungu kapena maso
• kutopa kwambiri
• zizindikiro ngati chimfine
• kupweteka kwa minofu, kukokana, kapena kufooka
• kugunda kwamtima kosasintha
• kutupa kwa manja, mapazi, mikono kapena miyendo
• kuvuta kupuma kapena kumeza

Isavuconazonium ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Isavuconazonium imabwera m'matumba ndipo chithuza chilichonse chimakhala ndi matumba awiri. Thumba lamanzere lili ndi desiccant (paketi yaying'ono yomwe imakhala ndi chinthu chomwe chimamwa chinyezi kuti mankhwala asamaume) ndipo thumba lamanja lili ndi mankhwala. Tsegulani mthumba wa isavuconazonium ndikusiya desiccant mu phukusi. Musachotse isavuconazonium pazolongedza zoyambirira mpaka mutakonzeka kumwa mankhwala anu. Musayike isavuconazonium m'mabokosi amapiritsi kapena okonza mapiritsi. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• mutu
• chizungulire
• kupweteka, kuwotcha, kapena kumva kulasalasa m'manja kapena m'mapazi
• Kusinza
• Kuvuta kuyang'ana
• sinthani tanthauzo la kukoma
• pakamwa pouma
• dzanzi pakamwa
• kutsegula m'mimba
• kusanza
• kufiira mwadzidzidzi kwa nkhope, khosi, kapena chifuwa chapamwamba
• nkhawa
• kusakhazikika
• kugunda kapena kugunda kwamtima mwachangu
• mphamvu ya maso ndi kuwala
• kupweteka pamodzi

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu akhoza kuyitanitsa mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira ku isavuconazonium.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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