Ixekizumab jekeseni

Zamkati

• Musanagwiritse ntchito jekeseni wa ixekizumab,
• Jekeseni wa Ixekizumab ungayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zalembedwa mu gawo la SPECIAL PRECAUTIONS, siyani kugwiritsa ntchito jakisoni wa ixekizumab ndipo itanani dokotala mwamsanga kapena pitani kuchipatala mwadzidzidzi:

Jekeseni wa Ixekizumab imagwiritsidwa ntchito pochizira zolembera zapakhosi psoriasis (matenda akhungu momwe mawonekedwe ofiira, amiyala amawumba m'malo ena amthupi) mwa akulu ndi ana azaka 6 kapena kupitilira apo omwe psoriasis yawo ndi yovuta kwambiri kuti angachiritsidwe ndi mankhwala apakhungu yekha. Amagwiritsidwanso ntchito payekha kapena kuphatikiza mankhwala ena monga methotrexate (Rasuvo, Trexall, ena) kuchiza nyamakazi ya psoriatic (vuto lomwe limayambitsa kupweteka kwamalumikizidwe ndi kutupa ndi mamba pakhungu) mwa akulu. Jekeseni wa Ixekizumab imagwiritsidwanso ntchito pochizira ankylosing spondylitis (momwe thupi limagwirira malo olumikizirana mafupa a msana ndi madera ena, ndikupangitsa kuwawa komanso kuwonongeka kwamagulu) mwa akulu. Amagwiritsidwanso ntchito pochiza spondyloarthritis (non-radiographic axial spondyloarthritis (momwe thupi limagwirira malo olumikizirana mafupa a msana ndi madera ena omwe amachititsa ululu ndi zizindikilo zotupa, koma osasintha pa x-ray) mwa akulu, jekeseni wa Ixekizumab ndi m'kalasi la mankhwala otchedwa monoclonal antibodies. Zimagwira ntchito poletsa kuchitapo kanthu kwa zinthu zina zachilengedwe m'thupi zomwe zimayambitsa zizindikiro za psoriasis.

Jekeseni wa Ixekizumab umadza ngati yankho (madzi) mu jakisoni woyikiratu komanso ngati autoinjector wodziyikira payokha (pansi pa khungu). Pochiza plaque psoriasis mwa akulu, nthawi zambiri amapatsidwa ngati jakisoni awiri pamlingo woyamba, wotsatiridwa ndi jakisoni m'masabata awiri aliwonse pamlingo 6 wotsatira, kenako jakisoni m'masabata anayi aliwonse. Pochizira plaque psoriasis mwa ana, nthawi zambiri amapatsidwa ngati jakisoni m'modzi kapena awiri pamlingo woyamba, kutengera kulemera kwa mwanayo, kutsatiridwa ndi jakisoni m'masabata anayi aliwonse. Pofuna kuchiza nyamakazi ya psoriatic kapena ankylosing spondylitis, nthawi zambiri amaperekedwa ngati jakisoni awiri pamlingo woyamba, kenako ndi jakisoni m'masabata anayi aliwonse. Pochiza non-radiographic axial spondyloarthritis, nthawi zambiri imaperekedwa ngati jekeseni imodzi pakatha milungu inayi.

Mutha kulandira mulingo wanu woyamba wa jekeseni wa ixekizumab muofesi ya dokotala wanu. Ngati ndinu wamkulu, dokotala wanu angakulolezeni kapena kukusamalirani kuti mupange jakisoni wa ixekizumab kunyumba mukamaliza kumwa mankhwala oyamba. Ngati muli ndi vuto la masomphenya kapena kumva, mufunika wosamalira ena kuti akupatseni jakisoni. Ngati mwana wanu akulemera mapaundi 110 (50 kg) kapena kuchepera, jakisoni wa ixekizumab ayenera kuperekedwa ku ofesi ya dokotala. Ngati mwana wanu akulemera mapaundi opitilira 110, dokotala wanu akhoza kuloleza womusamalira kuti abaye jakisoni kunyumba. Funsani dokotala wanu kapena wamankhwala kuti akuwonetseni inu kapena munthu yemwe ati adzalandire mankhwalawo momwe angabayire ndi kukonzekera.

Gwiritsani ntchito sirinji iliyonse kapena autoinjector kamodzi kokha ndikujambulitsa yankho lonse mu syringe kapena autoinjector. Kutaya ma syringe ogwiritsidwa ntchito ndi autoinjector muchidebe chosagwira. Lankhulani ndi dokotala wanu kapena wamankhwala za momwe mungatayire chidebe chosagwira mankhwala.

Chotsani jakisoni woyikiratu kapena autoinjector mufiriji. Ikani pamalo osanjikiza osachotsa chipewa cha singano ndikulola kutentha kwa mphindi 30 musanakonzekere kulandira mankhwala. Osayesa kutenthetsa mankhwalawo powotenthetsa mu microwave, ndikuyika m'madzi otentha, kuwasiya padzuwa, kapena njira ina iliyonse.

Musagwedeze syringe kapena autoinjector yomwe ili ndi ixekizumab.

Nthawi zonse yang'anani yankho la ixekizumab musanaibayize. Onetsetsani kuti tsiku lomaliza ladutsa komanso kuti madziwo ndiwowoneka bwino kapena wachikaso pang'ono. Madziwo sayenera kukhala ndi tinthu tomwe timawonekera. Musagwiritse ntchito syringe kapena autoinjector ngati yang'ambika kapena yathyoledwa, ikatha kapena itazizira, kapena ngati madzi ali mitambo kapena ali ndi tinthu tating'onoting'ono.

Mutha kubaya jekeseni wa ixekizumab paliponse patsogolo pa ntchafu zanu (mwendo wapamwamba) kapena pamimba (m'mimba) kupatula mchombo wanu ndi dera lomwe lili mainchesi (2.5 masentimita) mozungulira. Ngati muli ndi womusamalira kuti amubayire mankhwalawa, kumbuyo kwa mkono wanu amathanso kugwiritsidwa ntchito. Kuti muchepetse mwayi wowawa kapena kufiira, gwiritsani ntchito tsamba lina la jakisoni aliyense. Osalowetsa malo omwe khungu ndi lofewa, lophwanyika, lofiira, kapena lolimba kapena komwe muli ndi zipsera kapena zotambasula. Osabaya ixekizumab kudera lomwe lakhudzidwa ndi psoriasis.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide ndi Malangizo Ogwiritsira Ntchito) mukayamba chithandizo ndi jekeseni wa ixekizumab ndipo nthawi iliyonse mukamadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kuti mupeze Medication Guide, kapena tsamba laopanga kuti mupeze Medication Guide ndi Malangizo Zogwiritsa Ntchito.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanagwiritse ntchito jekeseni wa ixekizumab,

• uzani dokotala wanu komanso wamankhwala ngati mukugwirizana ndi ixekizumab, mankhwala ena aliwonse, kapena zosakaniza zilizonse mu jekeseni wa ixekizumab. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), cyclosporine (Gengraf, Neoral, Sandimmune), quinidine (ku Nuedexta), sirolimus (Rapamune), tacrolimus (Astagraf, Envarsus, Prograf) , ndi warfarin (Coumadin, Jantoven). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi jekeseni wa ixekizumab, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• Uzani dokotala wanu ngati muli ndi matenda kapena ngati mwakhalapo ndi matenda opatsirana (IBD; gulu la zinthu zomwe zimayambitsa kutupa kwa matumbo) monga matenda a Crohn (matenda omwe thupi limagunda Kuthira m'mimba, kuchititsa kupweteka, kutsegula m'mimba, kuchepa thupi, ndi malungo) kapena ulcerative colitis (vuto lomwe limayambitsa kutupa ndi zilonda mkatikati mwa matumbo [matumbo akulu] ndi rectum).
• uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukamagwiritsa ntchito jakisoni wa ixekizumab, itanani dokotala wanu.
• funsani dokotala wanu kuti muwone ngati mukufuna kulandira katemera uliwonse. Ndikofunika kukhala ndi katemera onse oyenera msinkhu wanu musanayambe mankhwala anu ndi jakisoni wa ixekizumab. Musakhale ndi katemera uliwonse mukamalandira chithandizo popanda kulankhula ndi dokotala.
• muyenera kudziwa kuti jakisoni wa ixekizumab amachepetsa kuthekera kwanu kothana ndi matenda kuchokera ku mabakiteriya, mavairasi, ndi bowa ndikuwonjezera chiopsezo choti mutenga matenda owopsa kapena owopsa. Uzani dokotala wanu ngati nthawi zambiri mumakhala ndi matenda aliwonse kapena ngati muli kapena mukuganiza kuti mutha kukhala ndi matenda aliwonse pano. Izi zimaphatikizapo matenda ang'onoang'ono (monga mabala otseguka kapena zilonda), matenda omwe amabwera (monga herpes kapena zilonda zozizira), ndi matenda opatsirana omwe samatha. Ngati mukumane ndi zizindikilo zotsatirazi mukamalandira chithandizo kudzera mu jakisoni wa ixekizumab, itanani dokotala wanu mwachangu: malungo, thukuta, kapena kuzizira, kupweteka kwa minofu, kupuma movutikira, ofunda, ofiira, kapena khungu lopweteka kapena zilonda m'thupi lanu, kutsekula m'mimba, kupweteka m'mimba, kukodza pafupipafupi, mwachangu, kapena kupweteka, kapena zizindikilo zina za matenda. Dokotala wanu akhoza kuchedwetsa chithandizo chanu ndi jakisoni wa ixekizumab ngati muli ndi matenda.
• muyenera kudziwa kuti kugwiritsa ntchito jakisoni wa ixekizumab kumawonjezera chiopsezo kuti mudzadwala chifuwa chachikulu (TB; matenda opatsirana m'mapapo), makamaka ngati muli ndi kachilombo ka TB koma mulibe zizindikiro zilizonse za matendawa. Uzani dokotala wanu ngati mwakhalapo ndi TB kapena mudakhalapo ndi TB, ngati mudakhala m'dziko lomwe TB imafala, kapena ngati mudakhalapo ndi munthu amene ali ndi TB. Dokotala wanu adzakuyesani khungu kuti muwone ngati muli ndi kachilombo ka TB kosagwira ntchito. Ngati ndi kotheka, dokotala wanu adzakupatsani mankhwala ochizira matendawa musanayambe kugwiritsa ntchito jakisoni wa ixekizumab. Ngati muli ndi zizindikiro zotsatirazi za chifuwa chachikulu cha TB, kapena ngati muli ndi zina mwazizindikiro mukamalandira chithandizo, pitani kuchipatala nthawi yomweyo: kutsokomola, kutsokomola magazi kapena ntchofu, kufooka kapena kutopa, kuonda, kusowa chilakolako, kuzizira, malungo , kapena thukuta usiku.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Gwiritsani ntchito mlingo womwe mwaphonya mukangokumbukira ndikupitiliza dongosolo lanu lokhazikika. Musagwiritse ntchito mlingo wawiri kuti mupange omwe mwaphonya.

Jekeseni wa Ixekizumab ungayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• ofiira, oyabwa, kapena amadzi
• yothina kapena yothamanga m'mphuno
• kufiira kapena kupweteka pamalo obayira
• kupweteka m'mimba
• kutsegula m'mimba (wopanda kapena magazi)
• kuonda

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zalembedwa mu gawo la SPECIAL PRECAUTIONS, siyani kugwiritsa ntchito jakisoni wa ixekizumab ndipo itanani dokotala mwamsanga kapena pitani kuchipatala mwadzidzidzi:

• kumva kukomoka
• kutupa kwa nkhope, zikope, lilime, kapena mmero
• zovuta kumeza kapena kupuma
• zolimba pachifuwa kapena pakhosi
• zidzolo
• ming'oma

Jekeseni wa Ixekizumab ungayambitse zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamagwiritsa ntchito mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe munabwera kuti muteteze ku kuwala, kutsekedwa mwamphamvu, komanso kuti ana asakufikire. Sungani jekeseni wa ixekizumab mufiriji, koma musayimitse. Ngati kuli kotheka, mutha kusunga jekeseni wa ixekizumab kutentha kwapakati kwa masiku asanu mu katoni yoyambirira kuti muteteze ku kuwala. Mukasunga kutentha, musabwezeretse jekeseni wa ixekizumab mufiriji. Tayani jakisoni wa ixekizumab ngati sakugwiritsidwa ntchito pasanathe masiku 5 kutentha.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu.

Ixekizumab autoinjector ili ndi magawo agalasi ndipo amayenera kusamalidwa mosamala. Ngati autoinjector igwera pamalo olimba, osayigwiritsa ntchito.

Musalole kuti wina aliyense agwiritse ntchito mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Taltz^®