Cabozantinib (khansa ya chiwindi ndi impso)

Zamkati

• Musanatenge cabozantinib (Cabometyx),
• Cabozantinib (Cabometyx) itha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:
• Zizindikiro za bongo zingaphatikizepo izi:

Cabozantinib (Cabometyx) imagwiritsidwa ntchito pochizira renal cell carcinoma (RCC; mtundu wa khansa womwe umayambira m'maselo a impso). Amagwiritsidwanso ntchito limodzi ndi nivolumab (Opdivo) kuchiza RCC yapamwamba mwa odwala omwe sanalandire chithandizo cha RCC. Cabozantinib (Cabometyx) imagwiritsidwanso ntchito pochizira hepatocellular carcinoma (HCC; mtundu wa khansa ya chiwindi) mwa anthu omwe kale amathandizidwa ndi sorafenib (Nexafar). Cabozantinib (Cabometyx) ili mgulu la mankhwala otchedwa kinase inhibitors. Zimagwira ntchito poletsa proteni yachilendo yomwe imawonetsa kuti ma cell a khansa achulukane. Izi zimathandiza kuchepetsa kapena kuletsa kufalikira kwa maselo a khansa.

Cabozantinib imapezekanso ngati kapisozi (Cometriq) yothandizira mtundu wina wa khansa ya chithokomiro. Makinawa amangopereka chidziwitso cha mapiritsi a cabozantinib (Cabometyx) a RCC kapena HCC. Ngati mukugwiritsa ntchito mankhwalawa ku khansa ya chithokomiro, werengani monograph yotchedwa cabozantinib (khansa ya chithokomiro).

Cabozantinib (Cabometyx) imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku opanda kanthu m'mimba, osachepera ola limodzi musanadye ndi maola awiri mutadya. Tengani cabozantinib (Cabometyx) mozungulira nthawi yomweyo tsiku lililonse. Kutalika kwa chithandizo chanu kumadalira momwe thupi lanu limayankhira ndi mankhwala komanso zovuta zomwe mumakumana nazo. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani cabozantinib (Cabometyx) ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi athunthu ndi galasi lathunthu (ma ola 8, 240 mL) amadzi. Osagawanika, kutafuna, kapena kuwaphwanya.

Dokotala wanu akhoza kuchepetsa kuchuluka kwa cabozantinib (Cabometyx) kapena kuyimitsa kwanthawi zonse kapena kwakanthawi kochepa ngati mukumana ndi zovuta zina. Onetsetsani kuti mwalankhula ndi adotolo momwe mukumvera mukamalandira cabozantinib (Cabometyx).

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge cabozantinib (Cabometyx),

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la cabozantinib (Cabometyx, Cometriq), mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a cabozantinib. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, zomwe mukumwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: boceprevir (Victrelis), carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), clarithromycin (Biaxin, ku Prevpac), conivaptan (Vaprisol), indinavir (Crixivan), itraconazole ( ), ketoconazole, nefazodone, nelfinavir (Viracept), phenobarbital, phenytoin (Dilantin, Phenytek), posaconazole (Noxafil), rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, ku Rifamate, Rifater, Rifater, Rifater) , ku Kaletra), saquinavir (Invirase), telithromycin (Ketek), ndi voriconazole (Vfend). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi cabozantinib (Cabometyx), onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
• Uzani dokotala wanu ngati mwangotuluka kumene mwachilendo kapena koopsa monga kutsokomola magazi, kusanza magazi, kapena malo okhala ndi magazi kapena akuda, ngati muli ndi bala lotseguka kapena lochiritsa, kapena ngati mwakhalapo ndi kuthamanga kwa magazi, kapena matenda a chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Muyenera kuyezetsa mimba musanayambe mankhwala ndi cabozantinib. Simuyenera kutenga pakati mukamalandira chithandizo komanso kwa miyezi 4 mutatha kumwa. Lankhulani ndi dokotala wanu za njira zolerera zomwe mungagwiritse ntchito mukamachiza. Mukakhala ndi pakati mukatenga cabozantinib (Cabometyx), itanani dokotala wanu mwachangu. Cabozantinib itha kuvulaza mwana wosabadwayo.
• Uzani dokotala wanu ngati mukuyamwitsa. Dokotala wanu angakuuzeni kuti musamamwe mkaka mukamamwa mankhwala komanso kwa miyezi 4 mutatha kumwa.
• Muyenera kudziwa kuti mankhwalawa amachepetsa kubereka kwa abambo ndi amai. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito cabozantinib (Cabometyx).
• ngati mukuchitidwa opaleshoni muuzeni adotolo kuti mukumwa cabozantinib (Cabometyx). Dokotala wanu angakuuzeni kuti musiye kumwa cabozantinib (Cabometyx) masiku 21 musanachite opareshoni kapena njira yanu, ndipo angakuuzeni nthawi yomwe muyenera kuyambiranso kumwa mankhwalawo.
• muyenera kudziwa kuti cabozantinib (Cabometyx) itha kubweretsa mavuto akulu nsagwada yanu. Dokotala wa mano ayenera kufufuza mano anu musanayambe kumwa cabozantinib komanso nthawi zonse mukamamwa mankhwala. Onetsetsani kutsuka mano ndikutsuka mkamwa mwanu moyenera mukamamwa cabozantinib (Cabometyx). Lankhulani ndi dokotala musanalandire chithandizo chilichonse cha mano mukamamwa mankhwalawa. Dokotala wanu angakuuzeni kuti musiye kumwa cabozantinib masiku osachepera 21 musanachite opaleshoni yamano.
• muyenera kudziwa kuti kuthamanga kwa magazi kwanu kumatha kuchulukanso mukamalandira chithandizo cha cabozantinib. Dokotala wanu angayang'anire kuthamanga kwa magazi musanamwe komanso mukamalandira chithandizo.

Musamamwe madzi amphesa kapena kudya zipatso zamphesa kapena zakudya zilizonse kapena zowonjezera zomwe zili ndi zipatso zamphesa kapena madzi amphesa mukamamwa mankhwalawa.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ndi ochepera maola 12 mpaka muyeso wanu wotsatira, tulukani mlingo womwe mwaphonya ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Cabozantinib (Cabometyx) itha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kudzimbidwa
• nseru
• kusanza
• kusintha kwa kulawa chakudya
• kufiira, kutupa, zilonda, kapena kupweteka mkamwa mwanu
• kusowa chilakolako
• kuonda
• kutopa kwambiri kapena kufooka
• khungu lotumbululuka
• khungu lowuma
• kuphipha kwa minofu
• kupweteka kwa mafupa, mikono, kapena miyendo
• mawu amasintha kapena kukodola
• amachepetsa machiritso

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• kupweteka pachifuwa, kupanikizika, kapena kukakamira
• kutsokomola magazi kapena magazi aundana
• kusanza komwe ndi kwamagazi kapena kumawoneka ngati malo a khofi
• Kutuluka magazi msambo kolemera kuposa masiku onse
• ofiira kapena akuda, chembetsani chopondapo
• kutsegula m'mimba
• kutuluka mwazi kwachilendo kapena kulemera kapena kuphwanya
• malo ofewa kapena opweteka m'mimba
• ofunda, ofiira, otupa, kapena manja ofewa kapena miyendo
• kutupa mozungulira maso, mikono, manja, miyendo, mapazi, kapena akakolo
• mkodzo wa thovu
• kupuma pang'ono kapena kutsokomola
• mutu mwadzidzidzi
• kupusa kapena kukomoka
• kulanda
• dzanzi kapena kufooka kwa nkhope, mkono, kapena mwendo mbali imodzi ya thupi lanu
• kuyenda mwadzidzidzi
• mavuto masomphenya mwadzidzidzi
• chisokonezo
• zovuta mwadzidzidzi kuganiza kapena kulankhula bwino
• zovuta mwadzidzidzi moyenera kapena mogwirizana
• chizungulire
• kutuluka thukuta kuposa masiku onse
• kupweteka kwa nsagwada
• Dzino likundiwawa
• kumasula mano
• Matama otupa kapena opweteka
• zidzolo
• kufiira, kupweteka, kutupa, kapena kuphulika pamanja kapena pansi
• kutopa kwambiri, chizungulire, kukomoka, kufooka, nseru, kapena kusanza
• chikasu cha khungu kapena maso, kutopa kwambiri, kutuluka magazi kapena kuvulala mosavuta, nseru kapena kusanza, kupweteka kwam'mimba kumanja, mkodzo wamdima wakuda, kuchepa kwa njala

Cabozantinib (Cabometyx) itha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• kuiwalika
• chisokonezo
• kuonda

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu akhoza kuyitanitsa mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira cabozantinib (Cabometyx).

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Zamgululi^®