Mlembi: Joan Hall
Tsiku La Chilengedwe: 25 Febuluwale 2021
Sinthani Tsiku: 21 Novembala 2024
Anonim
Rucaparib and Olaparib: Two New Treatments Approved for Advanced Prostate Cancer  | PCRI
Kanema: Rucaparib and Olaparib: Two New Treatments Approved for Advanced Prostate Cancer | PCRI

Zamkati

Rucaparib imagwiritsidwa ntchito kuthandizira kuthandizira chithandizo chamankhwala amitundu ina ya khansa yamchiberekero (khansa yomwe imayambira m'ziwalo zoberekera zachikazi momwe mazira amapangidwira), chubu (chotengera chomwe chimatumiza mazira otulutsidwa ndi thumba losunga mazira kupita m'chiberekero), komanso choyambirira khansa ya peritoneal (yomwe imayika pamimba) khansa yomwe yabwerera mwa achikulire omwe adayankha kwathunthu kapena pang'ono poyankha mankhwala ena a chemotherapy. Amagwiritsidwanso ntchito kuthana ndi mitundu ina ya khansa yamchiberekero, khansa ya mazira, komanso khansa yoyamba ya peritoneal mwa anthu omwe ali ndi jini linalake omwe alandila chithandizo chamankhwala osachepera awiri. Rucaparib imagwiritsidwanso ntchito pochiza mitundu ina ya khansa ya prostate yomwe yafalikira kumadera ena m'thupi mwa anthu omwe ali ndi jini linalake omwe alandiranso mankhwala ena. Rucaparib ali mgulu la mankhwala otchedwa poly (ADP-ribose) polymerase (PARP) inhibitors. Zimagwira ntchito popha ma cell a khansa.

Rucaparib imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa wopanda chakudya kawiri patsiku, pafupifupi maola 12 atasiyana. Tengani rucaparib mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani rucaparib ndendende monga mwalamulo. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.


Dokotala wanu angafunikire kuchedwetsa chithandizo chanu kapena kusintha kwa mlingo wa rucaparib kutengera kuyankha kwanu kuchipatala ndi zovuta zina zomwe mungakumane nazo. Lankhulani ndi dokotala wanu za momwe mukumvera mukamalandira chithandizo. Osasiya kumwa rucaparib osalankhula ndi dokotala.

Ngati musanza mutatenga rucaparib, musamwe mlingo wina. Pitirizani dongosolo lanu lokhazikika.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanatenge rucaparib,

  • uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la rucaparib, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a rucaparib. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
  • auzeni adotolo komanso asayansi yanu mankhwala ena omwe mumamwa kapena mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: warfarin (Coumadin, Jantoven). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi rucaparib, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
  • Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena konzekerani kukhala ndi mwana. Simuyenera kutenga pakati mukamamwa rucaparib. Muyenera kukayezetsa mimba musanayambe kumwa mankhwala. Gwiritsani ntchito njira yolerera yothandiza pakumwa mankhwala ndi rucaparib komanso kwa miyezi 6 mutapatsidwa mankhwala omaliza. Ngati ndinu wamwamuna, inu ndi mnzanuyo muyenera kugwiritsa ntchito njira zakulera mukamalandira chithandizo komanso kwa miyezi itatu mutalandira mankhwala omaliza. Lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Mukakhala ndi pakati mukamamwa rucaparib, itanani dokotala wanu.
  • Uzani dokotala wanu ngati mukufuna kuyamwitsa. Simuyenera kuyamwa mukamamwa mankhwala ndi rucaparib komanso kwa masabata awiri mutatha kumwa.
  • konzani kupewa kuwononga dzuwa kosafunikira kapena kwanthawi yayitali komanso kuvala zovala zoteteza, chipewa, magalasi, ndi zoteteza ku dzuwa. Rucaparib imatha kupangitsa khungu lanu kuzindikira kuwala kwa dzuwa.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.


Pitani muyezo womwe mwaphonya ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Rucaparib ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • nseru
  • kusanza
  • kudzimbidwa
  • kutsegula m'mimba
  • kupweteka m'mimba
  • kusowa chilakolako
  • kusakoma m'kamwa
  • kuyabwa
  • zilonda mkamwa
  • Kuchulukana kwa mphuno, mphuno yothamanga, kuyetsemula, zilonda zapakhosi kapena zotupa, kapena chifuwa

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

  • kufooka, kutopa, kutentha thupi, kuonda, kuvulaza kapena kutuluka magazi, kapena magazi mumkodzo kapena chopondapo
  • khungu lotumbululuka
  • kupuma movutikira
  • zidzolo

Rucaparib ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).


Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu musanayambe komanso munthawi zosiyanasiyana nthawi yonse yomwe mumalandira chithandizo kuti muwone momwe thupi lanu likuyankhira rucaparib. Nthawi zina, dokotala wanu amalamula kuti mukayesedwe labu musanayambe mankhwala anu kuti muwone ngati khansa yanu itha kuchiritsidwa ndi rucaparib.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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Idasinthidwa Komaliza - 07/15/2020

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