Deutetrabenazine

Zamkati

• Musanamwe deutetrabenazine,
• Deutetrabenazine angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, lekani kumwa deutetrabenazine ndipo itanani dokotala nthawi yomweyo kapena mupeze chithandizo chadzidzidzi:
• Zizindikiro za bongo zingaphatikizepo izi:

Deutetrabenazine imatha kukulitsa chiopsezo cha kukhumudwa kapena malingaliro ofuna kudzipha (kuganiza zodzipweteka kapena kudzipha kapena kukonzekera kapena kuyesa kutero) mwa anthu omwe ali ndi matenda a Huntington (matenda obadwa nawo omwe amachititsa kuwonongeka kwapang'onopang'ono kwamaselo amitsempha mu ubongo). Uzani dokotala wanu ngati mwakhalapo ndi vuto lakukhumudwa kapena ngati mudaganizapo zodzipweteka kapena kudzipha. Ngati muli ndi matenda a Huntington ndipo muli ndi nkhawa kapena muli ndi malingaliro ofuna kudzipha, dokotala wanu mwina angakuuzeni kuti musatenge deutetrabenazine. Inu, banja lanu, kapena wosamalira muyenera kuyimbira dokotala nthawi yomweyo mukakumana ndi izi: kukhumudwa kwatsopano kapena kukulirakulira, malingaliro odzivulaza kapena kudzipha nokha kapena kukonzekera kapena kuyesa kutero, kuda nkhawa kwambiri, kusokonezeka, kuvutika kugona kapena kugona, nkhanza kapena nkhanza, kukwiya, kuchita zinthu mosaganizira, kusakhazikika kwambiri, nkhawa, kusintha thupi, kusachita chidwi ndi kucheza, kuvuta kutchera khutu, kapena kusintha kwina kulikonse pamakhalidwe. Onetsetsani kuti achibale anu kapena omwe amakusamalirani amakufikirani pafupipafupi ndipo akudziwa zomwe zingakhale zovuta kuti athe kuyimbira adotolo ngati mukulephera kupeza chithandizo chanokha.

Sungani maimidwe onse ndi dokotala wanu. Dokotala wanu angafune kulankhula nanu zaumoyo wanu mukamamwa mankhwalawa.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba kulandira mankhwala ndi deutetrabenazine ndipo nthawi iliyonse mukadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Deutetrabenazine amagwiritsidwa ntchito pochizira chorea (mayendedwe mwadzidzidzi omwe simungathe kuwongolera) omwe amayamba chifukwa cha matenda a Huntington (matenda obadwa nawo omwe amachititsa kuwonongeka kwapang'onopang'ono kwamaselo amitsempha muubongo). Amagwiritsidwanso ntchito pochiza tardive dyskinesia (kuyenda kosalamulirika kwa nkhope, lilime, kapena ziwalo zina za thupi). Deutetrabenazine ali mgulu la mankhwala otchedwa vesicular monoamine transporter 2 (VMAT2) inhibitors. Zimagwira ntchito posintha zochitika za zinthu zina zachilengedwe muubongo zomwe zimakhudza mitsempha ndi minofu.

Deutetrabenazine imabwera ngati piritsi kuti itenge pakamwa. Kwa odwala omwe ali ndi matenda a Huntington, nthawi zambiri amatengedwa ndi chakudya kamodzi patsiku poyamba ndikuwonjezera kawiri patsiku. Kwa odwala omwe ali ndi tardive dyskinesia, nthawi zambiri amatengedwa ndi chakudya kawiri tsiku lililonse. Tengani deutetrabenazine nthawi yofanana tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani deutetrabenazine monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi lonse; osagawana, kutafuna, kapena kuwaphwanya.

Dokotala wanu mwina angakuyambitseni pa mlingo wochepa wa deutetrabenazine ndipo pang'onopang'ono muwonjezere mlingo wanu, osati kamodzi pa sabata.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanamwe deutetrabenazine,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la deutetrabenazine, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a deutetrabenazine. Zimagwira ntchito posintha zochitika za zinthu zina zachilengedwe muubongo. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala ngati mukumwa reserpine, tetrabenazine (Xenazine), valbenazine (Ingrezza), kapena monoamine oxidase (MAO) inhibitor monga isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil), selegiline (Eldepryll , Emsam, Zelapar), ndi tranylcypromine (Parnate), kapena ngati mwasiya kumwa monoamine oxidase inhibitor m'masabata awiri apitawa kapena mwasiya kumwa reserpine m'masiku 20 apitawa. Dokotala wanu angakuuzeni kuti simuyenera kumwa deutetrabenazine.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: mankhwala a nkhawa; anti-depressants monga bupropion (Aplenzin, Wellbutrin, Zyban), fluoxetine (Prozac, Sarafem, Selfemra), ndi paroxetine (Brisdelle, Paxil, Pexeva); antipsychotic monga chlorpromazine, haloperidol (Haldol), olanzapine (Zyprexa), quetiapine (Seroquel), risperidone (Risperdal), thioridazine, ndi ziprasidone (Geodon); mankhwala ena am'magazi osagwirizana monga amiodarone (Nexterone, Pacerone), procainamide, quinidine (ku Nuedexta), ndi sotalol (Betapace, Sorine, Sotylize); moxifloxacin (Avelox); mankhwala a khunyu; mankhwala ogonetsa, mapiritsi ogona, kapena opewetsa nkhawa. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• uzani dokotala wanu ngati muli ndi matenda a chiwindi. Dokotala wanu mwina angakuuzeni kuti musamwe deutetrabenazine.
• auzeni adotolo ngati mwakhalapo ndi matenda a QT (zomwe zimawonjezera chiopsezo chokhala ndi kugunda kwamtima kosafunikira komwe kumatha kukomoka kapena kufa mwadzidzidzi) kapena mtundu wina wamatenda osagwirizana ndi mtima kapena vuto la mtima. Muuzeni dokotala ngati muli ndi magazi ochepa a magnesium kapena potaziyamu m'magazi anu kapena khansa ya m'mawere.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga deutetrabenazine, itanani dokotala wanu.
• muyenera kudziwa kuti deutetrabenazine imatha kukupangitsani kugona kapena kuyambitsa kutopa. Osayendetsa galimoto kapena kugwiritsa ntchito makina mpaka mutadziwa momwe mankhwalawa amakukhudzirani.
• Muyenera kudziwa kuti mowa umatha kuwonjezera kugona komwe kumayambitsidwa ndi mankhwalawa.Musamwe mowa mukamamwa deutetrabenazine.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Ngati mwaphonya kumwa deutetrabenazine kupitilira sabata, lankhulani ndi dokotala musanayambenso kumwa. Muyenera kuti muyambenso kuyitenga pamlingo wotsika.

Deutetrabenazine angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutsegula m'mimba
• kudzimbidwa
• pakamwa pouma
• kutopa
• kupweteka kapena kutentha pakukodza
• kuvulaza
• matenda apamwamba opuma

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, lekani kumwa deutetrabenazine ndipo itanani dokotala nthawi yomweyo kapena mupeze chithandizo chadzidzidzi:

• malungo, thukuta, chisokonezo, kugunda kwamtima mwachangu kapena mosasinthasintha, komanso kuuma kwambiri kwa minofu
• kugwedeza, kuuma, kapena kuvuta kusuntha kapena kusunga malire
• kugwa
• kugunda kwamtima mosasinthasintha kapena mwachangu
• kukomoka

Deutetrabenazine imatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisunge kutentha komanso kutali ndi kuwala, kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• kupindika kapena kugwedeza kayendedwe
• kusuntha kwamaso mwachangu
• nseru
• kusanza
• thukuta
• kukhalitsa
• chisokonezo
• kutsegula m'mimba
• kuyerekezera zinthu m'maganizo (kuwona chinthu kapena mawu akumva omwe kulibe)
• kufiira kwa khungu
• Kugwedezeka kosalamulirika

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Austedo^®