Malo osambira

Zamkati

• Musanadye midostaurin,
• Midostaurin ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

Midostaurin imagwiritsidwa ntchito ndi mankhwala ena a chemotherapy kuti athetse mitundu ina ya matenda a khansa ya myeloid (AML; mtundu wa khansa yamagazi oyera). Midostaurin imagwiritsidwanso ntchito pamitundu ina ya mastocytosis (vuto lamagazi momwe mumakhala ma cell ambiri (mtundu wina wamaselo oyera amwazi)). Midostaurin ali mgulu la mankhwala otchedwa kinase inhibitors. Zimagwira ntchito poletsa mapuloteni achilendo omwe amawonetsa kuti ma cell a khansa achulukane. Izi zimathandiza kuletsa kufalikira kwa mlongoti ndi maselo a khansa.

Midostaurin amabwera ngati kapisozi woti amwe pakamwa. Nthawi zambiri amatengedwa ndi chakudya kawiri patsiku. Tengani midostaurin mozungulira nthawi zofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani midostaurin ndendende monga mwalamulo. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza makapisozi lonse; osatsegula kapena kuwaphwanya.

Ngati musanza mutatenga midostaurin, musamwe mlingo wina. Pitirizani dongosolo lanu lokhazikika.

Dokotala wanu akhoza kuchepetsa mlingo wa midostaurin kapena kukuuzani kuti musiye kumwa midostaurin kwakanthawi kapena kosatha mukamalandira chithandizo. Izi zimadalira zotsatira zoyipa zomwe mumakumana nazo. Lankhulani ndi dokotala wanu za momwe mukumvera mukamalandira chithandizo. Pitirizani kumwa midostaurin ngakhale mutakhala bwino. Osasiya kumwa midostaurin osalankhula ndi dokotala.

Dokotala wanu angakuuzeni kuti mumwe mankhwala kuti muchepetse kunyoza ndi kusanza musanafike mlingo uliwonse wa midostaurin.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanadye midostaurin,

• uzani dokotala wanu komanso wamankhwala ngati mukugwirizana ndi midostaurin, mankhwala ena aliwonse, kapena zosakaniza zilizonse mu makapisozi a midostaurin. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ena omwe simukupatsidwa, mavitamini, ndi zowonjezera zakudya zomwe mukumwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: boceprevir (sakupezekanso ku US; Victrelis); carbamazepine (Carbatrol, Equetro, Tegretol, ena); clarithromycin (Biaxin, mu Prevpac); diltiazem (Cardizem, Cartia, Tiazac, ena); enzalutamide (Xtandi); idelalisib (Zydelig); itraconazole (Onmel, Sporanox); ketoconazole (Nizoral); mankhwala omwe amachiza kachilombo ka HIV monga cobicistat (Tybost, ku Evotaz, ku Genvoya, ku Prezcobix, ku Stribild), elvitegravir (Vitekta), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, ku Kaletra , ku Technivie, ku Viekira), saquinavir (Invirase) ndi tipranavir (Aptivus); mitotane (Lysodren); nefazodone; phenytoin (Dilantin, Phenytek); posaconazole (Noxafil); rifampin (Rifadin, Rimactane, ku Rifamate, ku Rifater); troleandomycin (sikupezeka ku U.S.); ndi voriconazole (Vfend). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi midostaurin, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
• auzeni adotolo ngati mwakhala mukugunda pamtima mosasinthasintha, kuwonjezeka kwa QT (vuto la mtima lomwe lingayambitse kugunda kwamtima, kukomoka, kapena kufa mwadzidzidzi), mapapo, chiwindi, kapena matenda a impso.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Ngati ndinu wamkazi, simuyenera kutenga pakati mukamamwa midostaurin komanso kwa miyezi 4 mutatha kumwa. Muyenera kukhala ndi mayeso olakwika pathupi pasanathe masiku 7 musanayambe kumwa midostaurin. Lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Ngati ndinu wamwamuna, inu ndi mnzanuyo muyenera kugwiritsa ntchito njira zakulera mukamalandira chithandizo ndikupitiliza kugwiritsa ntchito njira zakulera kwa miyezi 4 mutatha kumwa. Ngati inu kapena mnzanu mumakhala ndi pakati mukatenga midostaurin, itanani dokotala wanu mwachangu. Midostaurin itha kuvulaza mwana wosabadwayo.
• Uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwa mukamamwa midostaurin komanso kwa miyezi 4 mutatha kumwa.
• Muyenera kudziwa kuti mankhwalawa amachepetsa kubereka kwa abambo ndi amai.

Lankhulani ndi dokotala wanu za kudya mphesa ndi kumwa madzi amphesa mukamamwa mankhwalawa.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Pitani muyezo womwe mwaphonya ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Midostaurin ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• kutsegula m'mimba
• mutu
• mwazi wa m'mphuno
• kutopa
• kufooka
• chizungulire
• kudzimbidwa
• zotupa m'mimba
• thukuta lowonjezeka
• kupweteka m'mimba
• zigamba zoyera kapena zilonda pamilomo kapena mkamwa ndi pakhosi
• kutupa kwa manja, mapazi, akakolo, kapena miyendo yakumunsi
• msana, fupa, olowa, chiwalo, kapena kupweteka kwa minofu
• kuvuta kugona kapena kugona

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• malungo, chifuwa, zilonda zapakhosi, kuzizira, ndi zizindikiro zina za matenda
• kugunda kwamtima msanga, kosasinthasintha, kapena kwamphamvu
• kupuma movutikira
• kupweteka pachifuwa
• kuchapa
• kutupa kwa milomo, lilime, kapena pakhosi
• kuvuta kupuma kapena kumeza
• ming'oma
• zidzolo
• kuyabwa
• chifuwa chatsopano kapena chowonjezeka
• kupuma
• kusanza magazi kapena zinthu zosanza zomwe zimawoneka ngati malo a khofi
• kutuluka mwachilendo kapena kuphwanya
• kutentha kapena kupweteka pokodza

Midostaurin ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu akhoza kuyitanitsa mayeso ena a labu kuti muwone kuyankha kwa thupi lanu ku midostaurin.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Sungani^®