Enasidenib

Zamkati

• Musanatenge enasidenib,
• Enasidenib ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, itanani dokotala wanu mwachangu:

Enasidenib itha kuyambitsa matenda owopsa kapena owopsa omwe amatchedwa kusiyanitsa. Dokotala wanu amayang'anitsitsa mosamala kuti awone ngati mukukula matendawa. Ngati mukumane ndi izi, itanani dokotala wanu nthawi yomweyo: malungo, kunenepa mwadzidzidzi, kuchepa pokodza, kutupa kwa mikono yanu, miyendo, khosi, kubuula, kapena malo am'munsi, kupuma movutikira, kupuma movutikira, kupweteka pachifuwa, chifuwa, kapena kupweteka kwa mafupa. Pachizindikiro choyamba kuti mukuyamba kusiyanitsa, dokotala wanu adzakupatsani mankhwala ochizira matendawa, ndipo angakuuzeni kuti musiye kumwa enasidenib kwakanthawi.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Chithandizo cha Mankhwala) mukayamba chithandizo ndi enasidenib ndipo nthawi iliyonse mukadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Enasidenib amagwiritsidwa ntchito pochiza mtundu winawake wa myeloid leukemia (AML; mtundu wa khansa womwe umayambira m'maselo oyera a magazi) omwe awonjezeka kapena kubweranso atalandira chithandizo ndi mankhwala ena a chemotherapy. Enasidenib ali mgulu la mankhwala otchedwa isocitrate dehydrongenase-2 (IDH2) inhibitor. Zimagwira pochepetsa kapena kuletsa kukula kwa maselo a khansa.

Enasidenib imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku kapena wopanda chakudya. Tengani enasidenib mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani enasidenib ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi athunthu ndi kapu (ma ola 240) ya madzi; osagawana, kutafuna, kapena kuwaphwanya.

Ngati musanza mutamwa mankhwala a enasidenib, tengani mlingo wina posachedwa tsiku lomwelo.

Dokotala wanu akhoza kuyimitsa chithandizo chanu kwakanthawi kapena kosatha, amachepetsa kuchuluka kwa enasidenib, kapena amakuthandizani ndi mankhwala ena kutengera zovuta zomwe mumakumana nazo. Onetsetsani kuti mwalankhula ndi dokotala za momwe mukumvera mukamalandira chithandizo. Osasiya kumwa enasidenib osalankhula ndi dokotala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge enasidenib,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la enasidenib, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a enasidenib. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena konzekerani kukhala ndi mwana. Simuyenera kutenga pakati mukatenga enasidenib. Muyenera kukhala ndi mayeso olakwika okhudzana ndi mimba musanayambe kumwa mankhwalawa. Gwiritsani ntchito njira yolerera yothandiza panthawi yomwe mukuchiritsidwa ndi enasidenib komanso mwezi umodzi mutatha kumwa. Ngati muli wamwamuna ndipo mnzanu atha kukhala ndi pakati, muyenera kugwiritsa ntchito njira yolerera yoyenerera mukamalandira chithandizo komanso mwezi umodzi mutamwa. Enasidenib ikhoza kuchepetsa kugwiritsa ntchito njira zina zakulera zam'kamwa kotero lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Ngati inu kapena mnzanu mutakhala ndi pakati mukatenga enasidenib, itanani dokotala wanu.
• Uzani dokotala wanu ngati mukuyamwitsa. Simukuyenera kuyamwa mukakhala enasidenib komanso mwezi umodzi mutatha kumwa.
• Muyenera kudziwa kuti mankhwalawa amachepetsa kubereka kwa abambo ndi amai. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito enasidenib.

Imwani madzi ambiri kapena madzi ena tsiku lililonse mukamamwa mankhwala ndi enasidenib,

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya mukangokumbukira tsiku lomwelo. Komabe, ngati lakhala kale tsiku lotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Enasidenib ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• kutsegula m'mimba
• kuchepa kudya
• sintha momwe zinthu zimamvekera

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, itanani dokotala wanu mwachangu:

• chikasu cha maso kapena khungu lako
• kutuluka kwa minofu kapena kugwedezeka; kutentha, kumenyedwa, kapena kumva kulira pakhungu; kugunda kwamtima kosasintha; kapena kugwidwa

Enasidenib ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa). Musachotse desiccant (paketi yaying'ono yophatikizidwa ndi mankhwala oti mutenge chinyezi) kuchokera mchidebecho.

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira ku enasidenib.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Idhifa^®