Doravirine

Zamkati

• Musanatenge doravirine,
• Doravirine imatha kubweretsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

Doravirine imagwiritsidwa ntchito limodzi ndi mankhwala ena kuchiza matenda a kachirombo ka HIV kwa anthu achikulire omwe sanalandire mankhwala ena a HIV. Amagwiritsidwanso ntchito m'malo mwa mankhwala omwe alipo pakadali pano mwa anthu ena omwe amamwa kale mankhwala a HIV. Doravirine ali mgulu la mankhwala otchedwa non-nucleoside reverse transcriptase inhibitors (NNRTIs). Zimagwira ntchito pochepetsa kuchuluka kwa kachilombo ka HIV m'magazi. Ngakhale doravirine sachiza kachilombo ka HIV, imatha kuchepetsa mwayi wanu wopeza matenda a immunodeficiency syndrome (AIDS) ndi matenda okhudzana ndi HIV monga matenda akulu kapena khansa. Kumwa mankhwalawa pamodzi ndi kugonana mosatekeseka ndikusintha zina pamoyo wanu kumachepetsa chiopsezo chotenga (kufalitsa) kachirombo ka HIV kwa anthu ena.

Doravirine amabwera ngati piritsi kuti atenge pakamwa. Nthawi zambiri amatengedwa popanda chakudya kamodzi patsiku. Tengani doravirine mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani doravirine ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Doravirine amathandiza kupewa kachilombo ka HIV koma samachiritsa. Pitirizani kumwa doravirine ngakhale mukumva bwino. Osasiya kumwa doravirine osalankhula ndi dokotala. Mukasiya kumwa doravirine kapena kusowa mankhwala, matenda anu akhoza kukhala ovuta kuchiza. Doravirine yanu ikayamba kuchepa, pezani zambiri kuchokera kwa dokotala kapena wamankhwala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge doravirine,

• Uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la doravirine, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a doravirine. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala ngati mukumwa carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), enzalutamide (Xtandi), mitotane (Lysodren), oxcarbazepine (Trileptal), phenobarbital, phenytoin (Dilantin, Phenytek), rifampin (Rifampin (Rifampin) mu Rifamate, mu Rifater), rifapentine (Priftin), kapena wort wa St. Dokotala wanu angakuuzeni kuti musatenge doravirine ngati mukumwa mankhwala amodzi kapena angapo kapena mwamwa kamodzi m'masabata 4 apitawa.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: efavirenz (Sustiva, ku Atripla), etravirine (Intelence), kapena nevirapine (Viramune). Komanso, uzani dokotala ngati mukumwa rifabutin (Mycobutin) kapena mwamwa masabata 4 apitawa. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi doravirine, chifukwa chake onetsetsani kuti muwauze adotolo zamankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• auzeni adotolo ngati mwadwala kapena simunakhalepo ndi matenda omwe samatha kapena omwe amabwera ndikadwala monga cytomegalovirus (CMV; matenda omwe amayambitsa matenda omwe ali ndi chitetezo chamthupi), mycobacterium avium complex disease (MAC; Matenda omwe amabwera chifukwa cha Edzi, chibayo, chifuwa chachikulu (TB; mtundu wamatenda am'mapapo) kapena matenda am'magazi (zomwe zimachitika chitetezo chamthupi chikamalimbana ndi maselo athanzi mthupi mosazindikira) monga Matenda a manda (momwe thupi limagwirira chithokomiro kuchititsa kuti likhale lopitilira muyeso), polymyositis (zomwe zimayambitsa kufooka kwa minofu koma osati zotupa pakhungu), Guillain-Barré syndrome (kufooka, kugwedezeka, komanso kufa ziwalo chifukwa cha kuwonongeka kwamitsempha mwadzidzidzi) , ndi autoimmune hepatitis (momwe maselo am'thupi amalimbana ndi chiwindi).
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Mukakhala ndi pakati mukatenga doravirine, itanani dokotala wanu. Uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwa ngati muli ndi kachilombo ka HIV kapena ngati mukumwa doravirine.
• muyenera kudziwa kuti pamene mukumwa mankhwala ochizira kachilombo ka HIV, chitetezo chanu cha mthupi chingakhale champhamvu ndikuyamba kulimbana ndi matenda ena omwe anali kale mthupi lanu kapena amayambitsa zina. Izi zitha kukupangitsani kukhala ndi zizindikilo za matendawa kapena mikhalidwe. Ngati muli ndi zizindikiro zatsopano kapena zowonjezereka mukamamwa mankhwala a doravirine onetsetsani kuti mwauza dokotala wanu.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Doravirine imatha kubweretsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• mutu
• kutopa
• kupweteka m'mimba
• maloto achilendo
• kuvuta kugona kapena kugona
• chizungulire

Doravirine imatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa). Osasunga mapiritsi mu bokosi lamapiritsi kapena lokonzekera mapiritsi. Musachotse desiccant (wouma) mu botolo.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi.M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira ku doravirine.

Sungani doravirine m'manja. Musayembekezere mpaka mutatsala pang'ono kumwa mankhwala kuti mudzaze mankhwala anu.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Pifeltro^®