Erdafitinib

Zamkati

• Musanatenge erdafitinib,
• Erdafitinib ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi chimodzi mwazizindikirozi, lekani kumwa erdafitinib ndikuyimbira dokotala nthawi yomweyo:

Erdafitinib amagwiritsidwa ntchito pochiza khansa ya m'mitsempha (khansara ya chikhodzodzo ndi mbali zina za thirakiti) yomwe imafalikira kumatumba oyandikira kapena ziwalo zina za thupi zomwe sizingachotsedwe ndi opareshoni ndipo zawonjezeka kwambiri mukamathandizidwa ndi ena mankhwala a chemotherapy. Erdafitinib ali mgulu la mankhwala otchedwa kinase inhibitors. Zimagwira ntchito poletsa proteni yachilendo yomwe imawonetsa kuti ma cell a khansa achulukane. Izi zimathandiza kuchepetsa kapena kuletsa kufalikira kwa maselo a khansa.

Erdafitinib imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku kapena wopanda chakudya. Tengani erdafitinib mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani erdafitinib ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi lonse; osagawana, kutafuna, kapena kuwaphwanya.

Ngati musanza mutatenga erdafitinib, musamwe mlingo wina. Pitirizani dongosolo lanu lokhazikika.

Dokotala wanu akhoza kuchepetsa mlingo wanu kapena kuimitsa kanthawi kochepa kapena kosatha ngati mukukumana ndi zovuta zina. Onetsetsani kuti muuze dokotala momwe mukumvera mukamalandira chithandizo cha erdafitinib. Osasiya kumwa erdafitinib osalankhula ndi dokotala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge erdafitinib,

• auzeni dokotala ndi wazamankhwala ngati muli ndi vuto la erdafitinib, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a erdafitinib. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: ma antifungals monga fluconazole (Diflucan), itraconazole (Sporonox, Onmel, Tolsura), ndi ketoconazole; carbamazepine (Carbatrol, Equetro, Tegretol, ena); kumvetsetsa; Mankhwala a kachilombo ka HIV monga efavirenz (Sustiva, ku Atripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, ku Kaletra, ku Viekira), ndi saquinavir (Fortovase, Invirase ); metformin (Fortamet, Glucophage, mu Actoplus Met, ena); nefazodone; phenobarbital; phenytoin (Dilantin, Phenytek;), rifampin (Rifadin, Rimactane, ku Rifater); ndi telithromycin (Ketek). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi erdafitinib, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• uzani dokotala ngati mwauzidwapo kuti muli ndi phosphorous yambiri yamagazi kapena ngati mwakhala mukukumana ndi mavuto amaso kapena masomphenya, kapena matenda a impso kapena chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena ngati mukufuna kukhala ndi mwana. Ngati ndinu wamkazi, muyenera kuyezetsa asanayambe kulandira chithandizo ndikugwiritsa ntchito njira zakulera kuti muchepetse mimba mukamalandira chithandizo komanso mwezi umodzi mutatha kumwa. Ngati ndinu wamwamuna, inu ndi mnzanuyo muyenera kugwiritsa ntchito njira zakulera mukamamwa mankhwala ndi erdafitinib komanso kwa mwezi umodzi mutatha kumwa. Lankhulani ndi dokotala wanu za njira zolerera zomwe mungagwiritse ntchito mukamachiza. Ngati inu kapena mnzanu mumakhala ndi pakati mukatenga erdafitinib, itanani dokotala wanu mwachangu. Erdafitinib atha kuvulaza mwana wosabadwayo.
• Uzani dokotala wanu ngati mukuyamwitsa. Simukuyenera kuyamwa mukamamwa erdafitinib komanso kwa mwezi umodzi mutalandira mankhwala omaliza.
• Muyenera kudziwa kuti mankhwalawa amachepetsa kubereka mwa amayi. Lankhulani ndi dokotala wanu za kuopsa kotenga erdafitinib.
• muyenera kudziwa kuti mankhwalawa amatha kuyambitsa maso owuma komanso mavuto ena amaso, omwe atha kukhala owopsa.Dokotala wanu angakuuzeni kuti mugwiritse ntchito misozi yokumba kapena mafuta amdontho m'maso mukamamwa ndi erdafitinib.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Ngati mukukumbukira mlingo womwe munaphonya patsiku lomwe mumayenera kumwa, tengani mlingo womwe mwaphonya mukangokumbukira tsiku lomwelo. Komabe, ngati simukumbukira mlingo womwe mwaphonya mpaka tsiku lotsatira, tulukani mlingo womwe mwaphonyawo ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Erdafitinib ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kutsegula m'mimba
• kusanza
• kudzimbidwa
• zilonda pamilomo, mkamwa, kapena pakhosi
• pakamwa pouma
• kusintha kwa kukoma
• kupweteka m'mimba
• kuchepa kudya
• kuonda
• kutsitsa tsitsi kosazolowereka kapena kutayika tsitsi
• malungo
• kupweteka kwa minofu kapena molumikizana
• kutentha pa nthawi yokodza
• kutopa kapena kutopa
• kupuma movutikira

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi chimodzi mwazizindikirozi, lekani kumwa erdafitinib ndikuyimbira dokotala nthawi yomweyo:

• kusawona bwino, kutayika kwa masomphenya, kapena zosintha zina
• msomali mavuto kapena kusintha
• khungu loyabwa, louma, kapena losweka
• zidzolo
• kutupa, kupweteka, kufiira, kapena khungu la zikhatho ndi mapazi

Erdafitinib ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu, dotolo wamaso, ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira erdafitinib.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Balversa^®