Mlembi: Clyde Lopez
Tsiku La Chilengedwe: 26 Kulayi 2021
Sinthani Tsiku: 15 Novembala 2024
Anonim
New Prescribing Information on Survival Benefit for Nubeqa® (Darolutamide) Approved
Kanema: New Prescribing Information on Survival Benefit for Nubeqa® (Darolutamide) Approved

Zamkati

Darolutamide amagwiritsidwa ntchito pochiza mitundu ina ya khansa ya prostate (khansa yomwe imayamba mu prostate [gland yamwamuna yobereka]) yomwe siinafalikire mbali zina za thupi mwa amuna omwe sanathandizidwe ndi mankhwala ena. Darolutamide ali mgulu la mankhwala otchedwa androgen receptor inhibitors. Zimagwira ntchito poletsa zotsatira za androgen (mahomoni oberekera amuna) kuti athetse kukula ndi kufalikira kwa maselo a khansa.

Darolutamide amabwera ngati piritsi kuti atenge pakamwa. Nthawi zambiri amatengedwa ndi chakudya kawiri patsiku. Tengani darolutamide mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani darolutamide ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi lonse; osagawana, kutafuna, kapena kuwaphwanya.

Dokotala wanu angakuuzeni kuti musiye kumwa darolutamide kwakanthawi kochepa kapena muchepetse mlingo wanu ngati mutakumana ndi zovuta panthawi yamankhwala anu. Onetsetsani kuti mwalankhula ndi dokotala za momwe mukumvera mukamalandira chithandizo cha darolutamide.


Ngati dokotala wanu wakulemberani mankhwala ena monga goserelin (Zoladex), histrelin (Supprelin LA, Vantas), leuprolide (Eligard, Lupron), kapena triptorelin (Trelstar) yothandizira khansa yanu ya prostate, muyenera kupitiriza kulandira mankhwalawa nthawi yanu chithandizo ndi darolutamide.

Pitirizani kumwa darolutamide ngakhale mukumva bwino. Osasiya kumwa darolutamide osalankhula ndi dokotala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge darolutamide,

  • auzeni dokotala wanu komanso wamankhwala ngati muli ndi vuto la darolutamide, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a darolutamide. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
  • auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: ma antifungal ena monga itraconazole (Sporanox) ndi ketoconazole (Nizoral), apalutamide, carbamazepine (Carbatrol, Equetro, Tegretol), clarithromycin (Biaxin); fosphenytoin (Cerebyx), phenytoin (Dilantin, Phenytek), rifampin (Rimactane, ku Rifamate, ku Rifater), ndi ritonavir (Norvir, ku Kaletra, ku Technivie). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi darolutamide, onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
  • uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka St. John's Wort.
  • uzani dokotala wanu ngati mwakhalapo ndi matenda a impso kapena chiwindi.
  • muyenera kudziwa kuti darolutamide amangogwiritsidwa ntchito mwa amuna. Azimayi sayenera kumwa mankhwalawa, makamaka ngati ali ndi pakati kapena akhoza kutenga pakati kapena akuyamwitsa. Ngati atengedwa ndi amayi apakati, darolutamide atha kuvulaza mwanayo. Ngati mayi wapakati atenga darolutamide, ayenera kuyimbira foni msanga. Ngati bwenzi lanu silili ndi pakati koma atha kukhala ndi pakati, inu ndi mnzanuyo muyenera kugwiritsa ntchito njira zakulera mukamalandira chithandizo komanso kwa sabata limodzi mutatha kumwa.
  • Muyenera kudziwa kuti mankhwalawa amachepetsa kubereka mwa amuna. Komabe, simuyenera kuganiza kuti mnzanuyo sangatenge mimba mukamalandira chithandizo.

Musadye zipatso zamphesa kapena kumwa madzi amphesa mukamamwa mankhwalawa.


Tengani mlingo womwe mwaphonya mukangokumbukira. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Darolutamide ingayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • kutopa kwambiri
  • kupweteka kwa mkono, mwendo, dzanja, kapena phazi

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

  • kupweteka kwa mkono, mwendo, dzanja, kapena phazi
  • zidzolo
  • magazi mkodzo
  • osakhoza kukodza
  • malungo, kupuma mofulumira komanso / kapena kupuma pang'ono, kapena kutsokomola

Darolutamide ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).


Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu akhoza kuyitanitsa mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira ku darolutamide.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

  • Nubeqa®
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