Jekeseni wa Fosphenytoin

Zamkati

• Asanalandire jakisoni wa fosphenytoin,
• Fophenytoin ingayambitse kuchuluka kwa shuga m'magazi anu. Lankhulani ndi dokotala wanu za zizindikiro za shuga wambiri wamagazi komanso zomwe muyenera kuchita mukakumana ndi izi.
• Jakisoni wa Fosphenytoin angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa mgulu la ZOYENERA, itanani dokotala wanu mwachangu:
• Zizindikiro za bongo zingaphatikizepo:

Mutha kukhala ndi kuthamanga kwa magazi koopsa kapena koopsa pamoyo kapena mtima wosakhazikika pomwe mukulandira jakisoni wa fosphenytoin kapena pambuyo pake. Uzani dokotala wanu ngati mwakhalapo ndi zingwe zosasinthasintha pamtima kapena zotchinga mtima (momwe magetsi samadutsidwira mwachizolowezi kuchokera kuzipinda zakumwamba zamkati mpaka kuzipinda zapansi). Dokotala wanu sangakonde kuti mulandire jakisoni wa fosphenytoin. Komanso, uzani dokotala ngati mwakhalapo ndi vuto la mtima kapena kuthamanga magazi. Ngati mukumane ndi izi, uzani dokotala nthawi yomweyo: chizungulire, kutopa, kugunda kwamtima mosasinthasintha, kapena kupweteka pachifuwa.

Mukalandira mlingo uliwonse wa jakisoni wa fosphenytoin kuchipatala, ndipo dokotala kapena namwino adzakuyang'anirani mosamala mukalandira mankhwalawo komanso kwa mphindi 10 mpaka 20 pambuyo pake.

Jakisoni wa Fosphenytoin amagwiritsidwa ntchito pochiza matenda opatsirana a tonic-clonic (omwe kale amadziwika kuti kugwidwa kwakukulu; kugwidwa komwe kumakhudza thupi lonse) ndikuchiza ndikupewa kugwidwa komwe kungayambike mkati kapena pambuyo pa opaleshoni ku ubongo kapena dongosolo lamanjenje. Jekeseni wa Fosphenytoin itha kugwiritsidwanso ntchito kuthana ndi kugwidwa kwamtundu wina mwa anthu omwe sangatenge phenytoin wamlomo. Fosphenytoin ali mgulu la mankhwala otchedwa anticonvulsants. Zimagwira ntchito pochepetsa magwiridwe antchito amagetsi muubongo.

Jakisoni wa Fosphenytoin amabwera ngati yankho (madzi) kuti alowemo kudzera m'mitsempha (mumtsempha) kapena mu mnofu (mu mnofu) ndi dokotala kapena namwino kuchipatala. Fosphenytoin ikabayidwa kudzera m'mitsempha, nthawi zambiri imabayidwa pang'onopang'ono. Nthawi zambiri mumalandira jakisoni wa fosphenytoin ndipo kutalika kwa chithandizo chanu kumadalira momwe thupi lanu limayankhira mankhwalawo. Dokotala wanu angakuuzeni kangati komwe mungalandire jakisoni wa fosphenytoin.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire jakisoni wa fosphenytoin,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi matupi awo sagwirizana ndi fosphenytoin, mankhwala ena a hydantoin monga ethotoin (Peganone) kapena phenytoin (Dilantin, Phenytek), mankhwala ena aliwonse, kapena chilichonse chothandizira mu jakisoni wa fosphenytoin Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu ngati mukumwa delavirdine (Rescriptor). Dokotala wanu mwina sakufuna kuti mulandire jakisoni wa fosphenytoin ngati mukumwa mankhwalawa.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: albendazole (Albenza); amiodarone (Nexterone, Pacerone); maanticoagulants ('oonda magazi') monga warfarin (Coumadin, Jantoven); mankhwala oletsa antifungal monga fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Onmel, Sporanox, Tolsura), miconazole (Oravig), posaconazole (Noxafil), ndi voriconazole (Vfend); ma antivirals ena monga efavirenz (Sustiva, ku Atripla), indinavir (Crixivan), lopinavir (ku Kaletra), nelfinavir (Viracept), ritonavir (Norvir, ku Kaletra), ndi saquinavir (Invirase); magazi; capecitabine (Xeloda); carboplatin; mankhwala enaake; chlordiazepoxide (Librium, ku Librax); mankhwala a cholesterol monga atorvastatin (Lipitor, mu Caduet), fluvastatin (Lescol), ndi simvastatin (Zocor, ku Vytorin); cisplatin; clozapine (Fazaclo, Versacloz); cyclosporine (Gengraf, Neoral, Sandimmune); diazepam (Valium); diazoxide (Proglycem); digoxin (Lanoxin); disopyramide (Norpace); disulfiram (Antabuse); doxorubicin (Doxil); doxycycline (Acticlate, Doryx, Monodox, Oracea, Vibramycin); fluorouril; fluoxetine (Prozac, Sarafem, mu Symbyax, ena); fluvoxamine (Luvox); kupatsidwa folic acid; fosamprenavir (Lexiva); furosemide (Lasix); H₂ otsutsa monga cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), ndi ranitidine (Zantac); njira zolerera za mahomoni (mapiritsi olera, zigamba, mphete, kapena jakisoni); mankhwala othandizira mahomoni (HRT); irinotecan (Camptosar); isoniazid (Laniazid, ku Rifamate, ku Rifater); mankhwala a matenda amisala ndi nseru; Mankhwala ena ogwidwa monga carbamazepine (Carbatrol, Equetro, Tegretol, ena), ethosuximide (Zarontin), felbamate (Felbatol), lamotrigine (Lamictal), methsuximide (Celontin), oxcarbazepine (Trilepta, Oxtellar XR), phenobar XR), phenobar ), ndi valproic acid (Depakene); methadone (Dolophine, Methadose); methotrexate (Otrexup, Rasuvo, Trexall, Xatmep); methylphenidate (Daytrana, Concerta, Metadate, Ritalin); mexiletine; nifedipine (Adalat, Procardia), nimodiwashpine (Nymalize), nisoldipine (Sular); omeprazole (Prilosec); oral steroids monga dexamethasone, methylprednisolone (Medrol), prednisolone, ndi prednisone (Rayos); paclitaxel (Abraxane, Taxol); paroxetine (Paxil, Pexeva); praziquantel (Biltricide); quetiapine (Seroquel); quinidine (mu Nuedexta); kuperekanso; rifampin (Rifadin, Rimactane, ku Rifamate, ku Rifater); kupweteka kwa salicylate kumachepetsa monga aspirin, choline magnesium trisalicylate, choline salicylate, diflunisal, magnesium salicylate (Doan's, ena), ndi salsalate; mankhwala opatsirana (Zoloft); mankhwala a sulfa; teniposide; theophylline (Elixophyllin, Theo-24, Theochron); ticlopidine; tolbutamide; trazodone; verapamil (Calan, Verelan, ku Tarka); kachilombo (Sabril); ndi vitamini D. Dokotala wanu angafunike kusintha mlingo wa mankhwala anu kapena kukuyang'anirani mosamala za zotsatirapo zake.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
• uzani dokotala wanu ngati mwakhalapo ndi vuto la chiwindi mukalandira jakisoni wa fosphenytoin kapena phenytoin. Dokotala wanu mwina sakufuna kuti mulandire jakisoni wa fosphenytoin.
• Uzani dokotala wanu ngati mumamwa kapena mwakhala mukumwapo mowa wambiri. Uzani dokotala wanu ngati mwayezetsa labotale yomwe yanena kuti muli ndi chiopsezo chobadwa nacho chomwe chimapangitsa kuti muthe kukhala ndi khungu lalikulu ku fosphenytoin. Komanso, uzani dokotala ngati mwakhalapo ndi matenda a shuga, porphyria (momwe zinthu zina zachilengedwe zimakhalira mthupi ndipo zimatha kupweteketsa m'mimba, kusintha kwamaganizidwe kapena machitidwe, kapena zizindikilo zina), milingo yotsika ya albin magazi, kapena matenda a impso kapena chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Lankhulani ndi dokotala wanu za njira zothandiza zolerera zomwe mungagwiritse ntchito mukamachiza. Fosphenytoin itha kuvulaza mwana wosabadwayo.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukulandira jakisoni wa fosphenytoin.
• lankhulani ndi dokotala wanu zakumwa koyenera kwa mowa mukamamwa mankhwalawa.
• lankhulani ndi dokotala wanu za njira yabwino yosamalirira mano, nkhama, ndi pakamwa mukamamwa jakisoni wa fosphenytoin. Ndikofunikira kuti musamalire pakamwa panu moyenera kuti muchepetse chiwopsezo cha kuwonongeka kwa chingamu chifukwa cha fosphenytoin.

Fophenytoin ingayambitse kuchuluka kwa shuga m'magazi anu. Lankhulani ndi dokotala wanu za zizindikiro za shuga wambiri wamagazi komanso zomwe muyenera kuchita mukakumana ndi izi.

Jakisoni wa Fosphenytoin angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kuyabwa, kuwotcha, kapena kumva kulasalasa
• mayendedwe osalamulirika amaso
• kusuntha kwa thupi
• kutayika kwa mgwirizano
• chisokonezo
• chizungulire
• kufooka
• kubvutika
• mawu osalankhula
• pakamwa pouma
• mutu
• amasintha momwe mumamvera kukoma
• mavuto owonera
• kulira kwa makutu kapena kumva kumva
• kudzimbidwa

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa mgulu la ZOYENERA, itanani dokotala wanu mwachangu:

• kutupa, kusintha, kapena kupweteka pamalo obayira
• matuza
• zidzolo
• ming'oma
• kutupa kwa maso, nkhope, mmero, kapena lilime
• kuvuta kupuma kapena kumeza
• ukali
• zotupa zotupa
• nseru
• kusanza
• chikasu cha khungu kapena maso
• kupweteka kumtunda chakumanja kwam'mimba
• kutopa kwambiri
• kuvulaza kapena kutuluka mwachilendo
• mawanga ofiira kapena ofiirira pakhungu
• kusowa chilakolako
• zizindikiro ngati chimfine
• malungo, zilonda zapakhosi, zotupa, zilonda mkamwa, kapena mabala osavuta, kapena kutupa kwa nkhope
• kutupa kwa mikono, manja, akakolo, kapena miyendo yakumunsi

Jakisoni wa Fosphenytoin angayambitse zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Kulandila fosphenytoin kumatha kuonjezera chiopsezo kuti mungadzakhale ndi vuto ndi ma lymph node anu kuphatikizapo matenda a Hodgkin (khansa yomwe imayamba m'mitsempha). Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa pochiza matenda anu.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

• nseru
• kusanza
• kutopa
• kukomoka
• kugunda kwamtima kosasintha
• mayendedwe osalamulirika amaso
• kutayika kwa mgwirizano
• mawu odekha kapena osalankhula
• kugwedezeka kosalamulirika kwa gawo lina la thupi

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu akhoza kuyitanitsa mayeso ena a labu kuti muwone kuyankha kwanu ku jakisoni wa fosphenytoin.

Musanayezetsedwe kwa labotale, uzani adotolo ndi omwe akuwalembera kuti mukulandira jakisoni wa fosphenytoin.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Cerebyx^®