Fenfluramine

Zamkati

• Musanatenge fenfluramine,
• Fenfluramine ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi chimodzi mwazizindikirozi kapena zomwe zalembedwa mgulu la CHENJEZO CHENJEZO kapena CHENJEZO LAPadera, siyani kumwa fenfluramine ndipo itanani dokotala wanu mwachangu kapena mupeze chithandizo chadzidzidzi:
• Zizindikiro za bongo zingaphatikizepo:

Fenfluramine imatha kubweretsa mavuto akulu amtima ndi mapapo. Uzani dokotala wanu ngati mwakhalapo ndi matenda amtima kapena am'mapapo. Dokotala wanu adzapanga echocardiogram (kuyesa komwe kumagwiritsa ntchito mafunde akumveka kuti muyese kuthekera kwa mtima wanu kupopera magazi) musanayambe kumwa fenfluramine, miyezi isanu ndi umodzi iliyonse mukamalandira chithandizo, komanso kamodzi pa miyezi 3 mpaka 6 mutalandira fenfluramine yanu yomaliza.Itanani dokotala wanu nthawi yomweyo ngati muli ndi zina mwazizindikiro mukamalandira chithandizo: kupuma pang'ono, kupweteka pachifuwa, kutopa kapena kufooka, kugunda kwamphamvu kapena kupweteketsa mtima makamaka makamaka pakuchita zambiri, kupepuka mutu, kukomoka, kugunda kosasinthasintha, mawondo kapena mapazi otupa, kapena Mtundu wabuluu kumilomo ndi khungu.

Chifukwa cha kuopsa kwa mankhwalawa, fenfluramine imangopezeka pokhapokha mu pulogalamu yapadera yogawa yogawa. Pulogalamu yotchedwa Fintepla Risk Evaluation and Mitigation Strategies (REMS). Inu, dokotala wanu, ndi pharmacy yanu muyenera kulembetsa nawo pulogalamu ya Fintepla REMS musanalandire.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena kuti aone momwe thupi lanu limayankhira fenfluramine.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba mankhwala ndi fenfluramine ndipo nthawi iliyonse mukamadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Fenfluramine imagwiritsidwa ntchito poletsa kugwa kwa ana azaka ziwiri kapena kupitilira apo omwe ali ndi matenda a Dravet (matenda omwe amayamba adakali ana ndipo amayamba kukomoka ndipo pambuyo pake atha kubweretsa kuchedwa kwachitukuko ndikusintha pakudya, kuyerekeza, komanso kuyenda). Fenfluramine ali mgulu la mankhwala otchedwa anticonvulsants. Sizikudziwika momwe fenfluramine imagwirira ntchito, koma imakulitsa kuchuluka kwa zinthu zachilengedwe muubongo zomwe zingachepetse kugwidwa.

Fenfluramine amabwera ngati yankho (madzi) kuti atenge pakamwa. Nthawi zambiri amatengedwa kawiri patsiku kapena wopanda chakudya. Tengani fenfluramine mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani fenfluramine ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Dokotala wanu mwina angakuyambitseni pa fenfluramine yocheperako pang'onopang'ono ndikuwonjezerani mlingo wanu, osapitilira kamodzi sabata iliyonse.

Gwiritsani ntchito syringe yapakamwa yomwe idabwera ndi mankhwalawa poyesa yankho. Musagwiritse ntchito supuni ya banja kuti muyese mlingo wanu. Masipuni apanyumba si zida zoyezera molondola, ndipo mutha kulandira mankhwala ochulukirapo kapena osakwanira mukayesa mlingo wanu ndi supuni ya tiyi ya banja. Muzimutsuka ndi jekeseni wam'kamwa ndi madzi apampopi oyera ndipo mulole kuti uume mouma ntchito mukamaliza. Gwiritsani ntchito syringe pakamwa nthawi iliyonse yomwe mumamwa mankhwalawo.

Ngati muli ndi nasogastric (NG) kapena chubu cha m'mimba, dokotala wanu kapena wamankhwala akufotokozerani momwe mungakonzekerere fenfluramine kuti ayendetse.

Fenfluramine amathandiza kuchepetsa khunyu, koma sawachiritsa. Pitirizani kumwa fenfluramine ngakhale mukumva bwino. Osasiya kumwa fenfluramine osalankhula ndi dokotala. Mukasiya kumwa fenfluramine mwadzidzidzi, mutha kukhala ndi zizindikilo zobwerera m'mbuyo monga kukomoka kwatsopano kapena kukulira. Dokotala wanu mwina amachepetsa mlingo wanu pang'onopang'ono.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge fenfluramine,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi fenfluramine, mankhwala ena aliwonse, kapena zosakaniza zilizonse mu fenfluramine yankho la m'kamwa. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• uzani dokotala ngati mukumwa kapena kulandira mankhwala otsatirawa kapena mwasiya kumwa masiku 14 apitawa: monoamine oxidase (MAO) inhibitors kuphatikiza isocarboxazid (Marplan), linezolid (Zyvox), methylene buluu, phenelzine (Nardil), selegiline ( Eldepryl, Emsam, Zelapar), ndi tranylcypromine (Parnate). Mukasiya kumwa fenfluramine, muyenera kudikirira masiku osachepera 14 musanayambe kumwa MAO inhibitor.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: antidepressants monga bupropion (Aplenzin, Wellbutrin); mankhwala a nkhawa; cyproheptadine; dextromethorphan (yomwe imapezeka m'mankhwala ambiri a chifuwa; ku Nuedexta); efavirenz (Sustiva); lifiyamu (Lithobid); mankhwala a matenda amisala; mankhwala a mutu waching'alang'ala monga almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), ndi zolmitriptan (Zomig); omeprazole (Prilosec); rifampin (Rifadin, Rimactane, ku Rifamate, ku Rifater); mankhwala ogonetsa; mankhwala a khunyu monga carbamazepine (Carbatrol, Equetro, Tegretol, Teril), clobazam (Onfi, Sympazan), phenobarbital, phenytoin (Dilantin, Phenytek), ndi stiripentol (Diamcomit); serotonin-reuptake inhibitors monga fluoxetine (Prozac, Sarafem, Selfemra), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), ndi sertraline (Zoloft); serotonin-norepinephrine reuptake inhibitors (SNRI) monga desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), levomilnacipran (Fetzima), milnacipran (Savella), ndi venlafaxine (Effexor); mapiritsi ogona; zotetezera; trazodone; ndi tricyclic antidepressants ('mood elevator') monga desipramine (Norpramin) kapena protriptyline (Vivactil). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi fenfluramine, chifukwa chake onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• uzani dokotala wanu za mankhwala azitsamba ndi zowonjezera zakudya zomwe mumamwa, makamaka wort St. John's and tryptophan.
• uzani dokotala wanu ngati mwakhalapo ndi glaucoma (kuthamanga kwambiri m'maso komwe kumatha kuyambitsa kutaya kwamaso) kapena kuthamanga kwa magazi. Komanso, uzani dokotala ngati mwakhalapo ndi vuto lakukhumudwa, mavuto amisala, malingaliro ofuna kudzipha kapena machitidwe kapena impso kapena matenda a chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga fenfluramine, itanani dokotala wanu.
• muyenera kudziwa kuti fenfluramine imatha kukupangitsani kugona komanso kukupangitsani kuti zizikhala zovuta kuchita zinthu zomwe zimafunikira kukhala tcheru kapena kulumikizana. Osayendetsa galimoto kapena kugwiritsa ntchito makina mpaka mutadziwa momwe mankhwalawa amakukhudzirani.
• Funsani adotolo za zakumwa zoledzeretsa komanso mankhwala okhala ndi mowa (chifuwa ndi zinthu zozizira, monga Nyquil, ndi zinthu zina zamadzimadzi) mukamamwa fenfluramine. Mowa umatha kuwonjezera kugona komwe kumayambitsidwa ndi mankhwalawa.
• muyenera kudziwa kuti thanzi lanu lamisala lingasinthe m'njira zosayembekezereka ndipo mutha kudzipha (kuganiza zodzipweteka kapena kudzipha nokha kapena kukonzekera kapena kuyesa kutero) mukamamwa fenfluramine. Chiwerengero chochepa cha achikulire ndi ana azaka 5 zakubadwa kapena kupitilira (pafupifupi 1 mwa anthu 500) omwe adatenga ma anticonvulsants, monga fenfluramine, kuti athetse mavuto osiyanasiyana panthawi yamaphunziro azachipatala adadzipha panthawi yomwe amalandira chithandizo. Ena mwa anthuwa adayamba kudzipha sabata limodzi atayamba kumwa mankhwalawo. Inu ndi dokotala wanu muwona ngati kuopsa kokumwa mankhwala a anticonvulsant ndiokulirapo kuposa kuopsa kosamwa mankhwalawo. Inu, banja lanu, kapena amene amakusamalirani muyenera kuyimbira dokotala nthawi yomweyo mukakumana ndi izi: mantha; kusakhazikika kapena kusakhazikika; kukwiya kwatsopano kapena kukulira, nkhawa, kapena kukhumudwa; kuchita zofuna zawo; kuvuta kugona kapena kugona; aukali, aukali, kapena achiwawa; mania (kukwiya, kusangalala modabwitsa); kuganiza zodzipweteka kapena kudzipha, kapena kukonzekera kapena kuyesa kutero; kapena kusintha kwina kulikonse pamakhalidwe kapena malingaliro. Onetsetsani kuti banja lanu kapena amene akukusamalirani akudziwa zomwe zingakhale zovuta kuti athe kuyimbira dokotala ngati mukulephera kupeza chithandizo chanokha.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Fenfluramine ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutsegula m'mimba
• kudzimbidwa
• kusanza
• kusakhazikika kapena mavuto poyenda
• kukhetsa kapena malovu opyola muyeso
• kuvuta kugona kapena kugona
• kugwa
• malungo, chifuwa, kapena zizindikiro zina za matenda

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi chimodzi mwazizindikirozi kapena zomwe zalembedwa mgulu la CHENJEZO CHENJEZO kapena CHENJEZO LAPadera, siyani kumwa fenfluramine ndipo itanani dokotala wanu mwachangu kapena mupeze chithandizo chadzidzidzi:

• kusokonezeka, kuyerekezera zinthu m'maganizo, kuyerekezera thupi, kutentha thupi, thukuta, chisokonezo, kugunda kwamtima, kuzizira, kuuma kwa minofu kapena kugwedezeka, kutayika kwa mgwirizano, nseru, kusanza, kapena kutsekula m'mimba
• kusawona bwino kapena masomphenya amasintha, kuphatikiza kuwona ma halos (mawonekedwe osalongosoka mozungulira zinthu) kapena madontho achikuda

Fenfluramine imatha kuyambitsa njala komanso kuwonda. Mukawona kuti mwana wanu akutaya thupi, itanani dokotala wanu. Dokotala wanu amayang'ana kukula ndi kulemera kwa mwana wanu mosamala. Lankhulani ndi dokotala wanu ngati muli ndi nkhawa zakukula kapena kulemera kwa mwana wanu akamamwa mankhwalawa.

Fenfluramine ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Sungani yankho pakamwa kutentha ndikutentha ndi kutentha kwambiri ndi chinyezi (osati kubafa). Osazizira kapena kuyimitsa njirayo. Chotsani yankho lililonse lomwe simunaligwiritse ntchito lomwe latsala miyezi itatu mutangotsegula botolo kapena "mutayike pambuyo" patsikulo, tsiku lililonse lifulumira.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

• ana otayirira
• kubwerera kumbuyo
• kuthamanga kapena kusakhazikika kwamtima
• kuchapa
• kusakhazikika
• nkhawa
• kunjenjemera
• kulanda
• chikomokere (kutaya chidziwitso kwakanthawi)
• kusokonezeka, kuyerekezera zinthu m'maganizo, kuyerekezera thupi, kutentha thupi, thukuta, chisokonezo, kugunda kwa mtima, kunjenjemera, kuuma kwa minofu kapena kugwedezeka, kutayika kwa mgwirizano, nseru, kusanza, kapena kutsegula m'mimba

Musalole kuti aliyense azimwa mankhwala anu. Fenfluramine ndichinthu cholamulidwa. Malangizo amatha kudzazidwanso kangapo; funsani wamankhwala wanu ngati muli ndi mafunso.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Fintepla^®