Azacitidine

Zamkati

• Musanatenge azacitidine,
• Azacitidine amatha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

Azacitidine amagwiritsidwa ntchito pochiza matenda oopsa a leukemia (AML; khansa yamagazi oyera) mwa akulu omwe adachita bwino atalandira chemotherapy, koma omwe sangathe kumaliza kuchiritsa. Azacitidine ali mgulu la mankhwala otchedwa demethylation agents. Zimagwira ntchito pothandiza mafupa kupanga maselo abwinobwino amwazi komanso kupha maselo osadziwika bwino.

Azacitidine amabwera ngati piritsi kuti atenge pakamwa. Nthawi zambiri amatengedwa wopanda chakudya kamodzi tsiku lililonse kwa masiku 14 oyambira masiku 28. Dokotala wanu adzasankha kangati zomwe muyenera kubwereza izi kutengera momwe mumayankhira mankhwalawa ndi zovuta zina zomwe mungakumane nazo. Tengani azacitidine mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani azacitidine ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi lonse; osagawana, kutafuna, kapena kuwaphwanya.

Ngati khungu lanu limakhudzana ndi ufa kuchokera mkati mwa mapiritsi, tsukani malo owonekera nthawi yomweyo ndi sopo. Ngati maso anu kapena pakamwa panu zimakhudzana ndi ufa kuchokera mkati mwa mapiritsi, tsitsani malowo nthawi yomweyo ndi madzi.

Dokotala wanu adzakupatsani mankhwala kuti muchepetse kunyoza komanso kusanza mphindi 30 musanalandire mlingo uliwonse wa azacitidine pazigawo ziwiri zoyambirira. Dokotala wanu akhoza kupitiliza kukupatsani mankhwalawa kwa nthawi ina, ngati kuli kofunikira.

Ngati musanza mutatenga azacitidine, musamwe mlingo wina. Pitirizani dongosolo lanu lokhazikika.

Dokotala wanu akhoza kuchepetsa mlingo wanu kapena kuimitsa kanthawi kochepa kapena kosatha ngati mukukumana ndi zovuta zina. Onetsetsani kuti muuze dokotala momwe mukumvera mukamalandira azacitidine.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge azacitidine,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la azacitidine, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a azacitidine. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• auzeni adotolo ngati mwadwalapo chiwindi kapena impso.
• uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena ngati mukufuna kukhala ndi mwana. Inu kapena mnzanu simuyenera kutenga pakati mukatenga azacitidine. Ngati ndinu wamkazi, muyenera kuyezetsa asanayambe kulandira chithandizo ndikugwiritsa ntchito njira zakulera kuti muchepetse mimba mukamalandira chithandizo komanso kwa miyezi isanu ndi umodzi mutatha kumwa. Ngati ndinu wamwamuna ndipo mnzanu atha kukhala ndi pakati, muyenera kugwiritsa ntchito njira yolerera yoyenerera mukamalandira chithandizo komanso kwa miyezi itatu mutalandira mankhwala. Ngati inu kapena mnzanu mumakhala ndi pakati mukatenga azacitidine, itanani dokotala wanu. Azacitidine atha kuvulaza mwana wosabadwayo.
• musamwe mkaka pamene mukumwa azacitidine komanso kwa sabata limodzi mutamwa mankhwala omaliza.
• Muyenera kudziwa kuti mankhwalawa amachepetsa kubereka kwa abambo ndi amai. Lankhulani ndi dokotala wanu za kuopsa kwakumwa azacitidine.
• muyenera kudziwa kuti azacitidine nthawi zambiri imayambitsa kutsegula m'mimba, komwe kumatha kukhala koopsa. Dokotala wanu angakuuzeni kuti mutenge mankhwala oletsa kutsegula m'mimba kuti muchepetse kuchepa kwa madzi m'thupi (kutaya madzi ochulukirapo m'thupi lanu) mukamalandira azacitidine.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Ngati mwaphonya mlingo kapena ngati simutenga mankhwala anu nthawi yokhazikika, imwani msanga tsiku lomwelo. Tengani mlingo wanu wotsatira nthawi yotsatira tsiku lotsatira. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Azacitidine amatha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• kutsegula m'mimba
• kudzimbidwa
• kusowa chilakolako
• kutopa
• kupweteka m'mimba
• kupweteka pamodzi
• kupweteka kwa minofu
• chizungulire
• kupweteka m'manja kapena miyendo

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• zilonda zapakhosi, malungo, kuzizira, kupweteka kwa thupi, kapena zizindikilo zina za matenda
• kupuma pang'ono kapena khungu lotumbululuka
• kuvulaza kapena kutuluka mwachilendo, masanzi amwazi, masanzi omwe amawoneka ngati malo a khofi, kapena akuda, kudikirira, kapena mipando yamagazi

Azacitidine amatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa). Sungani zidebe ziwiri za desiccant (zoyanika) mu botolo la mankhwala kuti mapiritsiwo asayume. Musadye zotsekemera za desiccant.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu musanachitike komanso mukamalandira chithandizo kuti muwone momwe thupi lanu likuyankhira azacitidine.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Onureg^®