Mlembi: Joan Hall
Tsiku La Chilengedwe: 1 Febuluwale 2021
Sinthani Tsiku: 22 Novembala 2024
Anonim
Acyclovir - Mechanism of Action, Indications, and Side Effects
Kanema: Acyclovir - Mechanism of Action, Indications, and Side Effects

Zamkati

Acyclovir imagwiritsidwa ntchito kuchepetsa kupweteka ndikufulumizitsa kuchiritsa zilonda kapena zotupa kwa anthu omwe ali ndi varicella (nkhuku), herpes zoster (shingles; Kuphulika kwa ziwalo zoberekera (matenda a herpes virus omwe amayambitsa zilonda kuzungulira ziwalo zoberekera ndi zotuluka nthawi ndi nthawi). Acyclovir imagwiritsidwanso ntchito popewa kuphulika kwa ziwalo zoberekera mwa anthu omwe ali ndi kachilomboka. Acyclovir ili m'kalasi la mankhwala ochepetsa ma virus otchedwa synthetic nucleoside analogues. Zimagwira ntchito poletsa kufalikira kwa kachilombo ka herpes m'thupi. Acyclovir sichiza matenda opatsirana pogonana ndipo mwina singaletse kufalikira kwa ziwalo zoberekera kwa anthu ena.

Acyclovir imabwera ngati piritsi, kapisozi, ndi kuyimitsidwa (madzi) kuti atenge pakamwa. Zimabweranso ngati piritsi lotchedwa buccal lomwe limachedwa kutulutsidwa kuti ligwiritsidwe ntchito kumtedza wapamwamba pakamwa. Mapiritsi, makapisozi, ndi kuyimitsa nthawi zambiri amatengedwa kapena opanda chakudya kawiri kapena kasanu patsiku kwa masiku 5 mpaka 10, kuyambira posachedwa pomwe zizindikiro zanu zayamba. Acyclovir ikagwiritsidwa ntchito popewa kuphulika kwa ziwalo zoberekera, nthawi zambiri amatengedwa kawiri kapena kasanu patsiku kwa miyezi 12. Pulogalamu yotulutsira mochedwa yotulutsa buccal nthawi zambiri imagwiritsidwa ntchito ndi chala chowuma ngati kamodzi kamodzi mkati mwa ola limodzi kutayirira, kufiira, kuwotcha kapena kumva kuzizira kwa zilonda kumayamba koma chisanu chisanachitike. Tengani kapena mugwiritse ntchito acyclovir mozungulira nthawi yofanana tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani kapena gwiritsani ntchito acyclovir monga momwe mwalamulira. Osamutenga kapena kuugwiritsa ntchito wocheperako kapena kumugwiritsa ntchito nthawi zambiri kapena kwa nthawi yayitali kuposa momwe adalangizira dokotala.


Osatafuna, kuphwanya, kuyamwa, kapena kumeza mapiritsi otchedwa buccal. Imwani zamadzimadzi zambiri, ngati muli ndi kamwa youma mukamagwiritsa ntchito mapiritsi otchedwa a buccal.

Kuti mugwiritse ntchito buccal acyclovir, tsatirani izi:

  1. Pezani dera lomwe lili pamwambapa pamwamba pamano anu akumanzere ndi kumanzere oyikirira (mano kumanzere ndi kumanzere kwa mano anu awiri akumaso).
  2. Ndi manja owuma, chotsani piritsi limodzi lotulutsidwa mochedwa.
  3. Pepani piritsi lanu kumtunda kwa chingamu chapamwamba kwambiri momwe lidzapitirire pa chingamu chanu pamwamba pa mano anu oyambira mbali yakumlomo kwanu ndi zilonda zozizira. Osayigwiritsa ntchito mkamwa kapena patsaya.
  4. Gwirani piritsi m'malo mwa masekondi 30.
  5. Ngati phale lanu silikumamatira ku chingamu chanu kapena ngati limamatira ku tsaya lanu kapena mkati mwa mlomo wanu, likonzeninso kuti likumirire kunkhama kwanu. Siyani piritsilo mpaka litasungunuka.
  6. Osasokoneza kuyika kwa piritsi. Onani ngati piritsiyo idakalipo mutadya, kumwa, kapena kutsuka mkamwa.

Ngati piritsi la buccal lotulutsidwa mochedwa lituluka mkati mwa maola 6 oyamba, ikani pulogalamu yomweyo. Ngati sichingakakamire, ikani pulogalamu yatsopano. Ngati mwameza piritsilo mwangozi mkati mwa maola 6 oyamba, mugwiritse madzi ndikumwa piritsi yatsopano. Ngati piritsiyo idagwa kapena kumeza 6 kapena kupitilira maola mutagwiritsa ntchito, musagwiritse ntchito piritsi yatsopano mpaka nthawi yanu yotsatira.


Pewani zotsatirazi mukamagwiritsa ntchito piritsi yotulutsa acyclovir buccal:

  • Osatafuna chingamu, kukhudza, kapena kukanikiza piritsi la buccal mutatha kuligwiritsa ntchito.
  • Osavala zodzikongoletsera zapamwamba.
  • Osatsuka mano mpaka itasungunuka. Ngati mano anu akuyenera kutsukidwa piritsi likadalipo, tsukutsani mkamwa pang'ono.

Sambani kuyimitsidwa bwino musanagwiritse ntchito kusakaniza mankhwala mofanana.

Zizindikiro zanu ziyenera kusintha mukamachiza acyclovir. Itanani dokotala wanu ngati matenda anu sakusintha kapena akukulirakulira.

Tengani kapena mugwiritse ntchito acyclovir mpaka mutha kumaliza mankhwala, ngakhale mutakhala bwino. Mukasiya kumwa acyclovir posachedwa kapena kudumpha mlingo, matenda anu sangachiritsidwe kwathunthu kapena atha kukhala ovuta kuwachiza. Pulogalamu yotulutsira mochedwa yotulutsidwa ya buccal imagwiritsidwa ntchito ngati kamodzi.

Acyclovir nthawi zina amagwiritsidwanso ntchito kuthana ndi eczema herpeticum (matenda apakhungu omwe amayamba chifukwa cha herpes virus) kuchiza ndikupewa matenda a herpes pakhungu, m'maso, mphuno, ndi pakamwa mwa odwala omwe ali ndi kachilombo ka HIV (HIV), ndikuchiza ubweya wam'kamwa leukoplakia (vuto lomwe limayambitsa zigamba zoyera kapena zotuwa pa lilime kapena mkati mwa tsaya).


Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge acyclovir,

  • uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la acyclovir, valacyclovir (Valtrex), mankhwala ena aliwonse, mapuloteni amkaka, kapena chilichonse mwazinthu zopangidwa ndi acyclovir. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
  • Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: amphotericin B (Fungizone); maantibayotiki aminoglycoside monga amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), neomycin (Nes-RX, Neo-Fradin), paramomycin (Humatin), streptomycin, ndi tobramycin (Tobi, Nebcin); aspirin ndi mankhwala ena osagwiritsa ntchito kutupa monga ibuprofen (Advil, Motrin), ndi naproxen (Aleve, Naprosyn); cyclosporine (Gengraf, Neoral, Sandimmune); mankhwala ochizira HIV kapena Edzi monga zidovudine (Retrovir, AZT); pentamidine (NebuPent); ma probenecid (Benemid); sulfonamides monga sulfamethoxazole ndi trimethoprim (Bactrim); tacrolimus (Prograf); ndi vancomycin. Mankhwala ena ambiri amathanso kulumikizana ndi acyclovir, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
  • uzani dokotala wanu ngati pali kuthekera kuti mutha kuchepa madzi m'thupi chifukwa cha matenda kapena zochita zaposachedwa, kapena ngati mwakhala mukukumana ndi mavuto ndi chitetezo chamthupi chanu; matenda opatsirana m'thupi (HIV); anapeza matenda a immunodeficiency (AIDS); kapena matenda a impso.
  • Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga acyclovir, itanani dokotala wanu.
  • ngati mukumwa acyclovir kuchiza matenda opatsirana pogonana, muyenera kudziwa kuti nsungu zoberekera zimatha kufalikira kudzera mukugonana ngakhale mulibe matuza kapena zizindikiro zina ndipo mwina ngakhale mutenga acyclovir. Lankhulani ndi dokotala wanu za njira zothetsera kufalikira kwa matenda opatsirana pogonana komanso ngati mnzanuyo ayenera kulandira chithandizo.

Imwani madzi ambiri mukamamwa kapena mukugwiritsa ntchito acyclovir.

Tengani mlingo womwe mwaphonya mukangokumbukira ndikumwa mankhwala omwe atsala tsiku lomwelo mosiyanasiyana. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Acyclovir angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • kukhumudwa m'mimba
  • kusanza
  • kutsegula m'mimba
  • chizungulire
  • kutopa
  • kubvutika
  • ululu, makamaka m'malo olumikizirana mafupa
  • kutayika tsitsi
  • kusintha kwa masomphenya

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo:

  • ming'oma
  • zidzolo kapena matuza
  • kuyabwa
  • kuvuta kupuma kapena kumeza
  • kutupa kwa nkhope, mmero, lilime, milomo, maso, manja, mapazi, akakolo, kapena miyendo yakumunsi
  • ukali
  • kugunda kwamtima mwachangu
  • kufooka
  • khungu lotumbululuka
  • kuvuta kugona
  • malungo, zilonda zapakhosi, kuzizira, chifuwa, ndi zizindikiro zina za matenda
  • kuvulaza kapena kutuluka mwachilendo
  • magazi mkodzo
  • kupweteka m'mimba kapena kukokana
  • kutsegula m'mimba
  • kuchepa pokodza
  • mutu
  • kuyerekezera zinthu m'maganizo (kuwona zinthu kapena kumva mawu omwe kulibe)
  • chisokonezo
  • nkhanza
  • zovuta kuyankhula
  • dzanzi, kutentha, kapena kumva kulasalasa m'manja kapena m'miyendo
  • kulephera kwakanthawi kusuntha ziwalo za thupi lanu
  • kugwedeza gawo la thupi lanu lomwe simungathe kulilamulira
  • kugwidwa
  • kutaya chidziwitso

Acyclovir ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa kapena kugwiritsa ntchito mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

  • kubvutika
  • kugwidwa
  • kutopa kwambiri
  • kutaya chidziwitso
  • kutupa kwa manja, mapazi, akakolo, kapena miyendo yakumunsi
  • kuchepa pokodza

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amatha kuyitanitsa mayeso ena a labu kuti muwone kuyankha kwanu ku acyclovir.

Musalole kuti aliyense azimwa kapena kugwiritsa ntchito mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

  • Sitavig®
  • Zovirax® Makapisozi
  • Zovirax® Mapiritsi
  • Acycloguanosine
  • ACV
Idasinthidwa Komaliza - 11/15/2019

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