Azathioprine

Zamkati

• Musanatenge azathioprine,
• Azathioprine amatha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu.
• Zizindikiro za bongo zingaphatikizepo izi:

Azathioprine akhoza kuonjezera chiopsezo chotenga mitundu ina ya khansa, makamaka khansa yapakhungu ndi lymphoma (khansa yomwe imayamba m'maselo omwe amalimbana ndi matenda). Ngati mudalandira impso, pakhoza kukhala pachiwopsezo chachikulu kuti mungakhale ndi khansa ngakhale simutenga azathioprine. Uzani dokotala wanu ngati mwakhalapo ndi khansa kapena ngati mumamwa kapena kumwa mankhwala a alkylating monga chlorambucil (Leukeran), cyclophosphamide (Cytoxan), kapena melphalan (Alkeran) ya khansa. Kuti muchepetse chiopsezo choti mungakhale ndi khansa yapakhungu, pewani kuwunika kwa nthawi yayitali kapena kosafunikira ndikuvala zovala zoteteza, magalasi a dzuwa, ndi zotchinga dzuwa. Uzani dokotala wanu nthawi yomweyo mukawona zosintha pakhungu lanu kapena zotupa zilizonse kapena misa paliponse mthupi lanu.

Achinyamata ena achikulire omwe amatenga azathioprine okha kapena ndi mankhwala ena otchedwa chotupa chotupa chotchedwa tumor necrosis factor (TNF) kuti athetse matenda a Crohn's (momwe thupi limagwirira mbali yam'mimba yomwe imayambitsa kupweteka, kutsegula m'mimba, kuchepa thupi, ndi malungo) kapena ulcerative colitis (vuto lomwe limayambitsa kutupa ndi zilonda mkatikati mwa matumbo [matumbo akulu] ndi rectum) zidapanga hepatosplenic T-cell lymphoma (HSTCL). HSTCL ndi khansa yoyipa kwambiri yomwe imayambitsa imfa munthawi yochepa. Azathioprine sanavomerezedwe ndi Food and Drug Administration (FDA) kuti azitha kuchiza matenda a Crohn's kapena ulcerative colitis, koma madotolo nthawi zina amatha kupereka azathioprine kuti athetse mikhalidwe imeneyi. Ngati mukukhala ndi zizindikilo izi mukamalandira chithandizo, pitani kuchipatala nthawi yomweyo: kupweteka m'mimba; malungo; kuwonda kosadziwika; Kutuluka thukuta usiku kapena kuvulaza kosavuta kapena kutuluka magazi.

Azathioprine ikhoza kuyambitsa kuchepa kwa maselo am'magazi m'mafupa anu, omwe angayambitse matenda oopsa kapena owopsa. Chiwopsezo choti kuchuluka kwamaselo amwazi omwe muli nawo chicheperako kwambiri ngati mungakhale pachiwopsezo chobadwa nawo. Dokotala wanu akhoza kuyitanitsa mayeso musanalandire kapena mukamalandira chithandizo kuti muwone ngati muli pachiwopsezo chotere. Kumwa mankhwala ena kungapangitsenso kuti magazi anu achepe, choncho uzani dokotala ngati mukumwa izi: angiotensin otembenuza enzyme (ACE) zoletsa monga benazepril (Lotensin), captopril, enalapril (Vasotec), fosinopril , lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), Ramipril (Altace), kapena trandolapril (Mavik); trimethoprim ndi sulfamethoxazole (Bactrim, Septra); ndi ribavirin (Copegus, Rebetol, Virazole). Ngati mukumane ndi izi, uzani dokotala nthawi yomweyo: kutuluka mwachilendo kapena kuvulala; kutopa kwambiri; khungu lotumbululuka; mutu; chisokonezo; chizungulire; kugunda kwamtima; kuvuta kugona; kufooka; kupuma movutikira; zilonda zapakhosi, malungo, kuzizira, ndi zizindikiro zina za matenda. Dokotala wanu adzaitanitsa mayesero musanapite, mkati, komanso mutatha chithandizo chanu kuti muwone ngati maselo anu amakhudzidwa ndi mankhwalawa.

Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa.

Azathioprine imagwiritsidwa ntchito ndi mankhwala ena kupewa kupewetsa kukanidwa (kuwonongeka kwa chitetezo chamthupi) mwa anthu omwe adalandilidwa impso. Amagwiritsidwanso ntchito pochiza nyamakazi ya nyamakazi (momwe thupi limagwirira mafupa ake, kupweteketsa, kutupa, komanso kutayika kwa ntchito) pomwe mankhwala ndi mankhwala ena sanathandize. Azathioprine ali mgulu la mankhwala otchedwa immunosuppressants. Zimagwira ntchito pochepetsa kuchepa kwa chitetezo cha mthupi kotero kuti sichidzawononga chiwalo chojambulidwa kapena malo olumikizirana.

Azathioprine amabwera ngati piritsi kuti atenge pakamwa. Nthawi zambiri amatengedwa kamodzi kapena kawiri patsiku mukatha kudya. Tengani azathioprine mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani azathioprine ndendende monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Ngati mukumwa azathioprine kuchiza nyamakazi, dokotala wanu akhoza kukuyambitsani pang'ono ndikuchulukitsa pang'onopang'ono pambuyo pa masabata 6-8 osapitilira kamodzi pakatha milungu inayi. Dokotala wanu akhoza kuchepetsa pang'onopang'ono mlingo wanu pamene matenda anu akuyang'aniridwa. Ngati mukumwa azathioprine kuti muchepetse kukanidwa kwa impso, dokotala wanu akhoza kukuyambitsani kwambiri ndikuchepetsa mlingo wanu pang'onopang'ono thupi lanu litasintha.

Azathioprine amalamulira nyamakazi koma samachiritsa. Zitha kutenga milungu 12 musanapindule ndi azathioprine. Azathioprine amalepheretsa kukanidwa pokhapokha mutamwa mankhwalawo. Pitilizani kumwa azathioprine ngakhale mukumva bwino. Osasiya kumwa azathioprine osalankhula ndi dokotala.

Azathioprine amagwiritsidwanso ntchito pochiza ulcerative colitis (vuto lomwe limayambitsa kutupa ndi zilonda mkatikati mwa colon [matumbo akulu] ndi rectum) ndi matenda a Crohn. Lankhulani ndi dokotala wanu za kuopsa kokugwiritsa ntchito mankhwalawa.

Mankhwalawa nthawi zina amapatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge azathioprine,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi azathioprine, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a azathioprine. Funsani dokotala wanu kapena wamankhwala mndandanda wa zosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchula mankhwala omwe atchulidwa mgawo la CHENJEZO LACHENJEZO ndi izi: allopurinol (Zyloprim); aminosalicylates monga mesalamine (Apriso, Asacol, Pentasa, ena), olsalazine (Dipentum), ndi sulfasalazine (Azulfidine); ndi maanticoagulants ('oonda magazi') monga warfarin (Coumadin). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• uzani dokotala wanu ngati muli ndi matenda amtundu uliwonse, kapena ngati mwakhalapo ndi matenda a impso.
• uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Muyenera kugwiritsa ntchito njira zolerera kuti muwonetsetse kuti inu kapena mnzanu simudzakhala ndi pakati mukamamwa mankhwalawa. Itanani dokotala wanu ngati inu kapena mnzanu muli ndi pakati mukatenga azathioprine. Azathioprine akhoza kuvulaza mwana wosabadwayo.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa azathioprine.
• mulibe katemera uliwonse mukamalandira chithandizo musanalankhule ndi dokotala.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Azathioprine amatha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• kutsegula m'mimba

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu.

• zidzolo
• malungo
• kufooka
• kupweteka kwa minofu

Mankhwalawa amatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa azathioprine.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• nseru
• kusanza
• kutsegula m'mimba
• zilonda zapakhosi, malungo, kuzizira, ndi zizindikiro zina za matenda

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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