Rifampin

Zamkati

• Musanamwe rifampin,
• Rifampin amatha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo:
• Zizindikiro za bongo zingaphatikizepo izi:

Rifampin amagwiritsidwa ntchito ndi mankhwala ena kuchiza chifuwa chachikulu (TB; matenda akulu omwe amakhudza mapapo ndipo nthawi zina mbali zina za thupi). Rifampin imagwiritsidwanso ntchito pochizira anthu ena omwe ali ndi Neisseria meningitidis (mtundu wa mabakiteriya omwe angayambitse matenda akulu otchedwa meningitis) m'mphuno kapena pakhosi. Anthuwa sanapeze zizindikiro za matendawa, ndipo mankhwalawa amawathandiza kuti asatengere anthu ena. Rifampin sayenera kugwiritsidwa ntchito pochiza anthu omwe ali ndi zizindikiro za meningitis. Rifampin ali mgulu la mankhwala otchedwa antimycobacterials. Zimagwira ntchito popha mabakiteriya omwe amayambitsa matenda.

Maantibayotiki monga rifampin sangagwire chimfine, kapena matenda ena a ma virus. Kugwiritsa ntchito maantibayotiki ngati sakufunika kumawonjezera chiopsezo chanu chotenga matenda pambuyo pake omwe amalephera kulandira mankhwala.

Rifampin amabwera ngati kapisozi woti amwe pakamwa. Iyenera kumwedwa ndi kapu yamadzi m'mimba yopanda kanthu, ola limodzi musanadye kapena maola awiri mutadya. Pamene rifampin imagwiritsidwa ntchito kuchiza TB, imamwa kamodzi patsiku. Pamene rifampin imagwiritsidwa ntchito popewa kufalikira kwa Neisseria meningitidis mabakiteriya kwa anthu ena, amatengedwa kawiri tsiku lililonse kwa masiku awiri kapena kamodzi tsiku lililonse kwa masiku anayi. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani rifampin ndendende monga momwe akuuzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Uzani dokotala wanu kapena wamankhwala ngati simungathe kumeza makapisozi. Wosunga mankhwala anu akhoza kukonzekera madzi oti mutenge m'malo mwake.

Ngati mukumwa rifampin kuchiza chifuwa chachikulu, dokotala wanu angakuuzeni kuti mutenge rifampin kwa miyezi ingapo kapena kupitilira apo. Pitirizani kumwa rifampin mpaka mutsirize mankhwalawa ngakhale mutakhala bwino, ndipo samalani kuti musaphonye mlingo. Mukasiya kumwa rifampin posachedwa, matenda anu sangachiritsidwe kwathunthu ndipo mabakiteriya amatha kulimbana ndi maantibayotiki. Mukaphonya mlingo wa rifampin, mutha kukhala ndi nkhawa kapena zizindikilo zoyipa mukayambiranso kumwa mankhwalawo.

Rifampin imagwiritsidwanso ntchito nthawi zina kuchiza matenda omwe amayambitsidwa ndi mitundu ina ya mabakiteriya komanso kupewa matenda mwa anthu omwe amalumikizana kwambiri ndi munthu yemwe ali ndi matenda ena obwera ndi mabakiteriya. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa ngati muli ndi vuto lanu.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanamwe rifampin,

• uzani dokotala ndi wamankhwala ngati muli ndi matupi awo sagwirizana ndi rifampin, rifabutin (Mycobutin), rifapentine (Priftin), mankhwala ena aliwonse, kapena chilichonse chosakaniza mu makapisozi a rifampin. Funsani dokotala wanu kapena wamankhwala mndandanda wa zosakaniza.
• Uzani dokotala ngati mukumwa mankhwala aliwonse awa: atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), praziquantel (Biltricide), saquinavir (Invirase), tipranavir (Aptivus), kapena ritonavir (Norvir) ndi saquinavir (Invirase) atengedwa pamodzi. Dokotala wanu angakuuzeni kuti musamwe rifampin ngati mukumwa mankhwala aliwonse. Ngati mukumwa rifampin ndipo mukufunika kumwa praziquantal (Biltricide), muyenera kuyembekezera pakadutsa milungu 4 mutasiya kumwa rifampin musanayambe kumwa praziquantel.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: maanticoagulants ('opopera magazi') monga warfarin (Coumadin, Jantoven); antifungals monga fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ndi ketoconazole; atovaquone (Mepron, ku Malarone); barbiturates monga phenobarbital; zotchinga beta monga atenolol (Tenormin), labetalol (Trandate), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), ndi propranolol (Inderal, Innopran); calcium blockers monga diltiazem (Cardizem, Cartia, Tiazac), nifedipine (Adalat, Procardia), ndi verapamil (Calan, Verelan); mankhwala enaake; clarithromycin (Biaxin); cyclosporine (Gengraf, Neoral, Sandimmune); daclatasvir (Daklinza); dapsone; diazepam (Valium); doxycycline (Monodox, Oracea, Vibramycin); efavirenz (Sustiva); enalapril (Vaseretic); fluoroquinolone maantibayotiki monga ciprofloxacin (Cipro) ndi moxifloxacin (Avelox); gemfibrozil (Lopid); haloperidol (Haldol); njira zolerera za mahomoni (mapiritsi olera, zigamba, mphete, kapena jakisoni); mankhwala othandizira mahomoni (HRT); indinavir (Crixivan); irinotecan (Camptosar); isoniazid (mu Rifater, Rifamate); levothyroxine (Levoxyl, Synthroid, Tirosint); losartan (Cozaar); mankhwala a kugunda kwamtima mosasinthasintha monga digoxin (Lanoxin), disopyramide (Norpace), mexiletine, propafenone (Rythmol), ndi quinidine (ku Nuedexta); mankhwala ogwidwa monga phenytoin (Dilantin, Phenytek); methadone (Dolophine, Methadose); mankhwala ozunguza bongo opweteka monga oxycodone (Oxaydo, Xtampza) ndi morphine (Kadian); ondansetron (Zofran, Zuplenz); mankhwala akumwa ashuga monga glipizide (Glucotrol), glyburide (Diabeta), ndi rosiglitazone (Avandia); zofufuza (Probalan); quinine (Qualquin); simvastatin (Flolipid, Zocor), ma steroids monga dexamethasone (Decadron), methylprednisolone (Medrol), ndi prednisone; sofosbuvir (Sovaldi); tamoxifen (Soltamox); toremifene (Fareston); trimethoprim ndi sulfamethoxazole (Bactrim, Septra); tacrolimus (Prograf); theophylline (Elixophyllin, Theo-24); tricyclic antidepressants monga amitriptyline ndi nortriptyline (Pamelor); zidovudine (Retrovir, mu Trizivir), ndi zolpidem (Ambien). Mankhwala ambiri amatha kulumikizana ndi rifampin, chifukwa chake onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• ngati mukumwa maantacid, tengani rifampin osachepera ola limodzi musanamwe ma antacids.
• Uzani dokotala wanu ngati mukumwa kapena mukugwiritsa ntchito njira zolerera za mahomoni (mapiritsi olerera, zigamba, mphete, zopangira, ndi jakisoni). Rifampin imatha kuchepetsa mphamvu yolera yakuchipatala. Muyenera kugwiritsa ntchito njira ina yolerera mukamamwa mankhwalawa. Lankhulani ndi dokotala wanu zakulera mukamamwa rifampin.
• Uzani dokotala ngati mwakhalapo ndi matenda a shuga, porphyria (momwe zinthu zina zachilengedwe zimakhalira mthupi ndipo zimatha kupweteketsa m'mimba, kusintha kwamaganizidwe ndi machitidwe, kapena zizindikilo zina), vuto lililonse lomwe limakhudza adrenal gland ( kanyama kakang'ono pafupi ndi impso kamene kamatulutsa zinthu zofunikira zachilengedwe) kapena matenda a chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga rifampin, itanani dokotala wanu.
• uzani dokotala wanu ngati muvala magalasi ofewa. Rifampin imatha kuyambitsa mabala ofiira osalekeza pamagalasi anu ngati muwavala mukamamwa mankhwala ndi rifampin.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Musaphonye Mlingo wa rifampin. Mlingo wosowa ungapangitse kuti mukhale ndi zovuta zina. Ngati mwaphonya mlingo, tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, tulukani mlingo womwe mwaphonya ndikuyimbira dokotala wanu. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Rifampin amatha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• Kutulutsa khungu kwakanthawi (chikaso, pabuka-lalanje, kapena bulauni) pakhungu lanu, mano, malovu, mkodzo, chopondapo, thukuta, ndi misozi)
• kuyabwa
• kuchapa
• mutu
• Kusinza
• chizungulire
• kusowa kwa mgwirizano
• zovuta kulingalira
• chisokonezo
• kusintha kwamakhalidwe
• kufooka kwa minofu
• dzanzi
• kupweteka m'manja, manja, mapazi, kapena miyendo
• kutentha pa chifuwa
• kukokana m'mimba
• kusowa chilakolako
• nseru
• kusanza
• kutsegula m'mimba
• mpweya
• msambo wopweteka kapena wosasamba
• masomphenya amasintha

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo:

• chimbudzi chamadzi kapena chamagazi, kukokana m'mimba, kapena malungo akamalandira chithandizo kapena kwa miyezi iwiri kapena kupitilira apo mutasiya kumwa mankhwala
• zidzolo; ming'oma; malungo; kuzizira; kutupa kwa maso, nkhope, milomo, lilime, kapena mmero; zovuta kumeza kapena kupuma; kupuma movutikira; kupuma; zotupa zaminyewa zotupa; chikhure; diso la pinki; zizindikiro ngati chimfine; kutuluka mwachilendo kapena kuvulala; kapena kutupa molumikizana kapena kupweteka
• nseru, kusanza, kusowa kwa njala, mkodzo wakuda, kapena chikasu pakhungu kapena m'maso

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Rifampin amatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• nseru
• kusanza
• kupweteka m'mimba
• kuyabwa
• mutu
• kutaya chidziwitso
• chikasu cha khungu kapena maso
• khungu lofiirira, malovu, mkodzo, ndowe, thukuta, ndi misozi
• kukoma kumtunda chakumanja kwam'mimba
• kutupa kwa maso kapena nkhope
• kuthamanga kapena kusakhazikika kwamtima
• kugwidwa

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone yankho lanu ku rifampin.

Musanapimidwe mayeso a labotale, kuphatikizapo kuyesa kuyezetsa mankhwala osokoneza bongo, auzeni ogwira nawo ntchito kuti mukumwa rifampin. Rifampin atha kuyambitsa zotsatira za mayeso ena owunikira mankhwala osokoneza bongo kukhala abwino ngakhale simunamwe mankhwalawo.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Rifadin^®
• Rimactane^®

• Yambitsani^® (okhala ndi Isoniazid, Rifampin)
• Mfuti^® (okhala ndi Isoniazid, Pyrazinamide, Rifampin)