Chlorpropamide

Zamkati

• Musanayambe kumwa mankhwala a chlorpropamide,
• Mankhwalawa amatha kusintha shuga m'magazi anu. Muyenera kudziwa zizindikiro za shuga wotsika kwambiri komanso zomwe muyenera kuchita ngati muli ndi izi.
• Chlorpropamide ikhoza kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:
• Zizindikiro za bongo zingaphatikizepo zizindikiro za hypoglycemia komanso izi:

Chlorpropamide sikupezeka ku United States.

Chlorpropamide imagwiritsidwa ntchito limodzi ndi zakudya komanso masewera olimbitsa thupi, ndipo nthawi zina ndimankhwala ena, kuchiza matenda ashuga amtundu wa 2 (momwe thupi siligwiritsa ntchito insulini mwachizolowezi, chifukwa chake, silingathe kuwongolera kuchuluka kwa shuga m'magazi). Chlorpropamide ili mgulu la mankhwala otchedwa sulfonylureas. Chlorpropamide imachepetsa shuga wamagazi popangitsa kuti kapamba apange insulin (chinthu chachilengedwe chomwe chimafunikira kuwononga shuga m'thupi) ndikuthandizira thupi kugwiritsa ntchito insulini moyenera. Mankhwalawa amangothandiza kuchepetsa shuga m'magazi mwa anthu omwe matupi awo amapanga insulin mwachilengedwe. Chlorpropamide sagwiritsidwa ntchito pochiza matenda ashuga amtundu wa 1 (momwe thupi silimatulutsa insulini, chifukwa chake, silingathe kuwongolera kuchuluka kwa shuga m'magazi) kapena matenda ashuga ketoacidosis (vuto lalikulu lomwe lingachitike ngati shuga wa magazi sanalandiridwe mankhwala ).

Popita nthawi, anthu omwe ali ndi matenda ashuga komanso shuga wambiri m'magazi amatha kukhala ndi mavuto owopsa kapena owopsa, kuphatikizapo matenda amtima, sitiroko, mavuto a impso, kuwonongeka kwa mitsempha, komanso mavuto amaso. Kumwa mankhwala (mankhwala), kusintha moyo wanu (mwachitsanzo, zakudya, kuchita masewera olimbitsa thupi, kusiya kusuta), komanso kuwunika shuga wanu wamagazi pafupipafupi kungakuthandizeni kuthana ndi matenda anu ashuga komanso kukhala ndi thanzi labwino. Mankhwalawa amathanso kuchepetsa mwayi wokhala ndi vuto la mtima, sitiroko, kapena zovuta zina zokhudzana ndi matenda ashuga monga impso kulephera, kuwonongeka kwamitsempha (dzanzi, miyendo yozizira kapena mapazi; kuchepa kwa kugonana kwa amuna ndi akazi), mavuto amaso, kuphatikiza kusintha kutaya masomphenya, kapena matenda a chiseyeye. Dokotala wanu ndi ena othandizira zaumoyo adzakambirana nanu za njira yabwino yothetsera matenda anu ashuga.

Chlorpropamide imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa ndi kadzutsa kamodzi patsiku. Uzani dokotala wanu ngati chlorpropamide imakhumudwitsa m'mimba mwanu. Dokotala wanu akhoza kukuwuzani kuti muzimwa mankhwala ochepa a chlorpropamide kawiri patsiku ndikudya. Kukuthandizani kukumbukira kukumbukira kumwa chlorpropamide, imwani nthawi yofanana tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani chlorpropamide ndendende monga momwe akuuzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Dokotala wanu mwina angakuyambitseni ndi mankhwala ochepa a chlorpropamide ndipo pang'onopang'ono muwonjezere mlingo wanu ngati mukufunikira. Mutamwa mankhwala a chlorpropamide kwakanthawi, chlorpropamide silingathe kuyendetsa shuga wamagazi komanso momwe inalili koyambirira kwa mankhwala anu. Dokotala wanu amatha kusintha mlingo wa mankhwala anu ngati mukufunikira kuti mankhwalawa azikugwirirani ntchito bwino. Onetsetsani kuti muuze dokotala momwe mukumvera komanso ngati zotsatira za mayeso anu a shuga akhala apamwamba kapena ocheperapo kuposa nthawi zonse mukamalandira chithandizo.

Chlorpropamide imathandiza kuchepetsa magazi koma sichiritsa matenda ashuga. Pitirizani kumwa chlorpropamide ngakhale mukumva bwino. Osasiya kumwa mankhwala a chlorpropamide osalankhula ndi dokotala.

Mankhwalawa nthawi zina amapatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanayambe kumwa mankhwala a chlorpropamide,

• uzani dokotala ndi wamankhwala ngati mankhwala a chlorpropamide, mankhwala ena aliwonse, kapena mankhwala ena aliwonse a chlorpropamide amakupatsani. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchula ma anticoagulants ('magazi opopera magazi') monga warfarin (Coumadin); aspirin ndi mankhwala ena osagwiritsa ntchito kutupa (NSAIDs) monga ibuprofen (Advil, Motrin) ndi naproxen (Aleve, Naprosyn); barbiturates monga amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), phenobarbital, ndi secobarbital (Seconal); zotchinga beta monga atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), ndi propranolol (Inderal); calcium blockers monga amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac, ena), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotop), nisold Sular), ndi verapamil (Calan, Isoptin, Verelan); mankhwala enaake; okodzetsa ('mapiritsi amadzi'); fluconazole (Diflucan); mankhwala obwezeretsa mahomoni ndi njira zolerera za mahomoni (mapiritsi olera, zigamba, mphete, zopangira, ndi jakisoni); insulin kapena mankhwala ena ochiza shuga kapena magazi ashuga; isoniazid (INH); MaO inhibitors monga isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), ndi tranylcypromine (Parnate); mankhwala a mphumu ndi chimfine; mankhwala a matenda amisala ndi nseru; miconazole (Monistat); kachilombo; mankhwala amlomo monga dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), ndi prednisone (Deltasone); phenytoin (Dilantin); ma probenecid (Benemid); kupweteka kwa salicylate kumachepetsa monga choline magnesium trisalicylate, choline salicylate (Arthropan), diflunisal (Dolobid), magnesium salicylate (Doan's, ena), ndi salsalate (Argesic, Disalcid, Salgesic); mankhwala a sulfa monga co-trimoxazole (Bactrim, Septra); sulfasalazine (Azulfidine); ndi mankhwala a chithokomiro. Onetsetsani kuti muuze dokotala kapena wamankhwala mukasiya kumwa mankhwala aliwonse mukamamwa mankhwala a chlorpropamide. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• auzeni adotolo ngati muli ndi vuto la G6PD (cholowa chomwe chimayambitsa kuwonongeka msanga kwa maselo ofiira kapena kuchepa kwa magazi m'thupi); ngati muli ndi vuto la mahomoni okhudzana ndi adrenal, pituitary, kapena chithokomiro; kapena ngati muli ndi matenda a mtima, impso, kapena chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga chlorpropamide, itanani dokotala wanu.
• lankhulani ndi dokotala wanu za kuopsa ndi maubwino otenga chlorpropamide ngati muli ndi zaka 65 kapena kupitilira apo.Okalamba sayenera kumwa chlorpropamide chifukwa siotetezeka kapena yothandiza ngati mankhwala ena omwe angagwiritsidwe ntchito kuthana ndi vuto lomwelo.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani adotolo kapena dokotala kuti mukumwa mankhwala a chlorpropamide.
• Funsani dokotala wanu za zakumwa zoledzeretsa pamene mukumwa mankhwalawa. Mowa umatha kukulitsa mavuto amtundu wa chlorpropamide. Kumwa mowa mukamamwa mankhwala otchedwa chlorpropamide kungayambitsenso zizindikiro monga kutsuka (kufiira nkhope), kupweteka mutu, kusanza, kusanza, kupweteka pachifuwa, kufooka, kusawona bwino, kusokonezeka m'maganizo, kutuluka thukuta, kutsamwa, kupuma movutikira, komanso nkhawa.
• konzekerani kupeŵa kuwunika kwa dzuwa kosafunikira kapena kwanthawi yayitali komanso kuvala zovala zoteteza, magalasi a dzuwa, ndi zoteteza ku dzuwa. Chlorpropamide imatha kupangitsa khungu lanu kuzindikira dzuwa.
• funsani dokotala wanu choti muchite mukadwala, mutenga matenda kapena malungo, mukumva kupsinjika kwachilendo, kapena mukavulala. Izi zimatha kukhudza shuga wamagazi ndi kuchuluka kwa chlorpropamide komwe mungafune.

Onetsetsani kuti mukutsatira zolimbitsa thupi komanso malingaliro azakudya zomwe adokotala anu kapena odyetsa. Ndikofunika kudya chakudya chopatsa thanzi, kuchita masewera olimbitsa thupi nthawi zonse, komanso kuonda ngati kuli kofunikira.

Musanayambe kumwa mankhwala a chlorpropamide, funsani dokotala zomwe muyenera kuchita mukaiwala kumwa mankhwala. Lembani malangizo awa kuti muthe kuwawunikiranso mtsogolo.

Monga mwalamulo, tengani mlingo womwe mwaphonya mukangokumbukira. Ngati ili pafupi nthawi ya mlingo wotsatira, tambani mlingo womwe mwaphonya ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Mankhwalawa amatha kusintha shuga m'magazi anu. Muyenera kudziwa zizindikiro za shuga wotsika kwambiri komanso zomwe muyenera kuchita ngati muli ndi izi.

Chlorpropamide ikhoza kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• kusowa chilakolako
• njala
• chizungulire
• mutu
• kuyabwa

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

• chikasu cha khungu kapena maso
• mipando yoyera
• mkodzo wakuda
• kupweteka kumtunda chakumanja kwam'mimba
• kuvulaza kapena kutuluka mwachilendo
• kutsegula m'mimba
• malungo
• chikhure
• zidzolo

Chlorpropamide ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Kafukufuku wina, anthu omwe adamwa mankhwala ofanana ndi chlorpropamide kuti athe kuchiza matenda awo ashuga amatha kufa ndi mavuto amtima kuposa omwe amathandizidwa ndi insulin komanso kusintha kwa zakudya. Lankhulani ndi dokotala wanu za kuopsa kotenga chlorpropamide.

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo zizindikiro za hypoglycemia komanso izi:

• kugwidwa
• kutaya chidziwitso

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Shuga wamagazi anu ndi hemoglobin ya m'magazi (HbA1c) iyenera kufufuzidwa pafupipafupi kuti mudziwe yankho lanu ku chlorpropamide. Dokotala wanu amatha kuyitanitsa mayeso ena a labu kuti muwone kuyankha kwanu ku chlorpropamide. Dokotala wanu adzakuwuzani momwe mungayang'anire kuyankha kwanu kwa mankhwalawa poyeza kuchuluka kwa shuga wamagazi kunyumba. Tsatirani malangizowa mosamala.

Muyenera kuvala chibangili chizindikiritso cha ashuga kuti mutsimikizire kuti mumalandira chithandizo chadzidzidzi pakagwa mwadzidzidzi.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Zamgululi^®
• Glucamide^®¶

^¶ Chogulitsa ichi sichikupezeka pamsika. Njira zina zitha kupezeka.