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Zamkati

• Musanatenge mercaptopurine,
• Mercaptopurine imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:
• Zizindikiro za bongo zingaphatikizepo:

Mercaptopurine imagwiritsidwa ntchito yokha kapena ndi mankhwala ena a chemotherapy kuti athetse khansa ya m'magazi (YONSE; yomwe imadziwikanso kuti khansa ya m'magazi ya lymphoblastic ndi acute lymphatic leukemia; mtundu wa khansa yomwe imayamba m'maselo oyera a magazi). Mercaptopurine ili mgulu la mankhwala otchedwa purine antagonists. Zimagwira ntchito poletsa kukula kwa maselo a khansa.

Mercaptopurine imabwera ngati piritsi komanso kuyimitsidwa (madzi) kuti mutenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku. Tengani mercaptopurine mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani mercaptopurine chimodzimodzi monga momwe mwauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Ngati mukuyimitsa, sinthani botolo bwino kwa masekondi 30 musanagwiritse ntchito kusakaniza mankhwala mofanana. Ndikofunikira kugwiritsa ntchito syringe yapakamwa (choyezera) kuti muyese molondola ndikumwa mankhwala anu a mercaptopurine. Ngati simukupeza jakisoni wam'kamwa ndi mankhwala anu, funsani wamankhwala wanu kuti akupatseni. Mutagwiritsa ntchito syringe pakamwa kuti mumwe mankhwala anu, chotsani chojambulira pazida zonsezo, tsukani mbali zonsezo ndi madzi ofunda sopo, ndikutsuka pansi pamadzi apampopi. Lolani kuti ziume ziume musanayanjanenso kuti mugwiritse ntchito.

Pitirizani kumwa mankhwala otchedwa mercaptopurine ngakhale mukumva bwino. Osasiya kumwa mankhwala a mercaptopurine osalankhula ndi dokotala

Mercaptopurine imagwiritsidwanso ntchito pochiza mitundu ina ya khansa, matenda a Crohn (matenda omwe thupi limagwiritsa ntchito gawo lakumagazi kumabweretsa ululu, kutsegula m'mimba, kuchepa thupi, ndi malungo), ndi ulcerative colitis (momwe zilonda zimakhalira m'matumbo oyambitsa kupweteka ndi kutsegula m'mimba). Lankhulani ndi dokotala wanu za kuopsa kokugwiritsa ntchito mankhwalawa.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge mercaptopurine,

• Uzani dokotala ndi wazamankhwala ngati muli ndi vuto la mankhwala a mercaptopurine, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a mercaptopurine kapena kuyimitsidwa. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: allopurinol (Lopurin, Zyloprim); aminosalicylates monga mesalamine (Apriso, Asacol, Canasa, Lialda, Delzicol, Pentasa, ena), olsalazine (Dipentum), ndi sulfasalazine (Azulfidine); maanticoagulants ('oonda magazi') monga warfarin (Coumadin, Jantoven); doxorubicin (Doxil); ndi trimethoprim ndi sulfamethoxazole (Bactrim, Septra). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• auzeni adotolo ngati mwamwa kale mercaptopurine kapena thioguanine kuti muchiritse khansa yanu.Dokotala wanu angakuuzeni kuti musatenge mankhwala a mercaptopurine ngati mankhwalawa sakugwira ntchito bwino motsutsana ndi khansa yanu m'mbuyomu.
• uzani dokotala wanu ngati muli ndi matenda amtundu uliwonse komanso ngati mwakhalapo ndi matenda a chiwindi kapena impso.
• uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Muyenera kugwiritsa ntchito njira zakulera kuti musatenge mimba mukamamwa mankhwala a mercaptopurine. Mukakhala ndi pakati mukatenga mankhwala a mercaptopurine, itanani dokotala wanu mwachangu. Mercaptopurine itha kuvulaza mwana wosabadwayo.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa mankhwala a mercaptopurine.
• mulibe katemera popanda kulankhula ndi dokotala.
• muyenera kudziwa kuti chiwopsezo choti mungakhale ndi zovuta zoyipa za mercaptopurine chitha kukhala chachikulu ngati muli ndi vuto lobadwa nalo. Dokotala wanu amatha kuyitanitsa mayeso musanachitike kapena mukamalandira chithandizo kuti muwone ngati muli pachiwopsezo chotere.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Mercaptopurine imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• mdima wa khungu
• kutayika tsitsi
• zidzolo

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

• khungu lotumbululuka
• kufooka
• kupuma movutikira
• zilonda zapakhosi, malungo, kuzizira, kapena zizindikilo zina za matenda
• kutupa miyendo, akakolo, kapena mapazi
• kuvulaza kapena kutuluka mwachilendo
• chikasu cha khungu kapena maso
• kusowa chilakolako
• kutsegula m'mimba
• kutupa kwa m'mimba
• kupweteka kumtunda chakumanja kwam'mimba

Kutenga mercaptopurine kumawonjezera chiopsezo kuti mungakhale ndi khansa yatsopano. Anthu ena omwe adatenga mercaptopurine kuchiza matenda a Crohn's or ulcerative colitis adayamba hepatosplenic T cell lymphoma (HSTCL), khansa yoopsa kwambiri yomwe nthawi zambiri imayambitsa kufa m'kanthawi kochepa. Uzani dokotala wanu ngati mukumane ndi izi: kupweteka m'mimba; malungo; kuwonda kosadziwika; Kutuluka thukuta usiku kapena kuvulaza kosavuta kapena kutuluka magazi. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa.

Mercaptopurine ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa). Kuyimitsidwa kwa Mercaptopurine kumatha kusungidwa kutentha mpaka milungu isanu ndi umodzi botolo litatsegulidwa koyamba. Kenako, tulutsani kuyimitsidwa kulikonse komwe kwatsala pambuyo pa milungu 6.

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

• kusowa chilakolako
• nseru
• kusanza
• kutsegula m'mimba
• khungu lotumbululuka
• kufooka
• kupuma movutikira
• zilonda zapakhosi, malungo, kuzizira, ndi zizindikiro zina za matenda
• kuvulaza kapena kutuluka mwachilendo

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone momwe thupi lanu lingayankhire mankhwala a mercaptopurine.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Purinethol^®
• Purixan^®

• 6-MP