Colchicine

Zamkati

• Musanatenge colchicine,
• Colchicine imatha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zizindikiro izi zili zazikulu kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, siyani kumwa colchicine ndipo itanani dokotala nthawi yomweyo:
• Zizindikiro za bongo zingaphatikizepo:

Colchicine imagwiritsidwa ntchito popewa kuukira kwa gout (mwadzidzidzi, kupweteka kwambiri pachimodzi kapena zingapo zomwe zimayambitsidwa ndi milingo yayikulu kwambiri yotchedwa uric acid m'magazi) mwa akulu. Colchicine (Colcrys) imagwiritsidwanso ntchito kuthana ndi zowawa za gout zikachitika. Colchicine (Colcrys) imagwiritsidwanso ntchito pochiza matenda a Mediterranean fever (FMF; matenda obadwa nawo omwe amayambitsa ziwalo za malungo, kupweteka, ndi kutupa kwa m'mimba, mapapo, ndi mafupa) mwa akulu ndi ana azaka 4 kapena kupitirira. Colchicine sichimapweteka ndipo sichingagwiritsidwe ntchito kuthana ndi ululu wosayambitsidwa ndi gout kapena FMF. Colchicine ali mgulu la mankhwala otchedwa anti-gout agents. Zimagwira poyimitsa njira zachilengedwe zomwe zimayambitsa kutupa ndi zizindikilo zina za gout ndi FMF.

Colchicine imabwera ngati piritsi ndi yankho (madzi; Gloperba) kumwa pakamwa kapena wopanda chakudya. Colchicine ikagwiritsidwa ntchito popewa matenda a gout kapena kuchiza FMF, imangotengedwa kamodzi kapena kawiri patsiku. Colchicine (Colcrys) imagwiritsidwa ntchito kuthetsa kupweteka kwa gout, mlingo umodzi nthawi zambiri umatengedwa pachizindikiro choyamba cha ululu ndipo wachiwiri, wocheperako nthawi zambiri amatengedwa ola limodzi pambuyo pake. Ngati simumva mpumulo kapena kudwalanso pakatha masiku angapo mutalandira chithandizo, lankhulani ndi dokotala musanamwe mankhwala owonjezera. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani colchicine ndendende monga mwalamulo. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Ndikofunikira kugwiritsa ntchito syringe ya m'kamwa (choyezera) kuti muyese molondola kuchuluka kwa madzi pamlingo uliwonse; osagwiritsa ntchito supuni ya banja.

Ngati mukumwa colchicine (Colcrys) kuti muchiritse FMF, dokotala wanu akhoza kukuyambitsani pamlingo wotsika ndikuwonjezera mlingo wanu pang'onopang'ono. Dokotala wanu akhoza kuchepetsa mlingo wanu ngati mukukumana ndi zovuta.

Ngati mukumwa colchicine kuti muteteze kuukira kwa gout, itanani dokotala wanu nthawi yomweyo mukakumana ndi gout mukamalandira chithandizo. Dokotala wanu angakuuzeni kuti mutenge mlingo wowonjezera wa colchicine, kenako ndi kamphindi kakang'ono ola limodzi pambuyo pake. Ngati mutenga mankhwala owonjezera a colchicine kuti muthane ndi gout, simuyenera kumwa mlingo wa colchicine mpaka mutadutsa maola 12 mutalandira mankhwala owonjezera.

Colchicine imatha kuletsa kuukira kwa gout ndikuwongolera FMF pokhapokha mutamwa mankhwalawo. Pitirizani kumwa colchicine ngakhale mukumva bwino. Osasiya kumwa colchicine osalankhula ndi dokotala.

Mankhwalawa amatha kupatsidwa ntchito zina. Funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge colchicine,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la colchicine, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a colchicine kapena yankho. Funsani dokotala wanu kapena wamankhwala kapena onani malangizo a mankhwala kuti muwone mndandanda wa zosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala omwe simukulembera, mavitamini, zakudya zopatsa thanzi, ndi mankhwala azitsamba omwe mukuwatenga, omwe mwamwa m'masiku 14 apitawa, kapena mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: maantibayotiki monga azithromycin (Zithromax), clarithromycin (Biaxin), erythromycin (EES, E-Mycin), telithromycin (Ketek; sapezeka ku U.S.); antifungals monga fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), ndi posaconazole (Noxafil); Aprepitant (Emend); mankhwala ochepetsa mafuta m'thupi (ma statins) monga atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor), pravastatin (Pravachol), ndi simvastatin (Zocor); cyclosporine (GenGraf, Neoral, Sandimmune); digoxin (Digitek, Lanoxin); diltiazem (Cardizem, Dilacor, Tiazac, ena); mafinya monga bezafibrate, fenofibrate (Antara, Lipofen), ndi gemfibrozil (Lopid); mankhwala a HIV kapena Edzi monga amprenavir (Agenerase), atazanavir (Reyataz), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (ku Kaletra, Norvir), ndi saquinavir (Invirase); nefazodone; ranolazine (Ranexa); ndi verapamil (Calan, Covera, Isoptin, Verelan). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi colchicine, onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• Uzani dokotala wanu ngati mwakhalapo ndi matenda a impso kapena a chiwindi. Dokotala wanu angakuuzeni kuti musatenge colchicine ngati mukumwa mankhwala ena aliwonse kapena ngati muli ndi matenda a impso ndi chiwindi.
• uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga colchicine, itanani dokotala wanu.

Musadye zipatso zamphesa kapena kumwa madzi amphesa mukamamwa mankhwala a colchicine.

Tengani mlingo womwe mwaphonya mukangokumbukira. Ngati mukumwa colchicine pafupipafupi ndipo ili pafupi nthawi yamphatso yotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Komabe, ngati mukumwa colchicine (Colcrys) kuti muchiritse kuukira kwa gout komwe kumachitika mukamamwa colchicine popewa gout ndikuyiwala kutenga mlingo wachiwiri, tengani mlingo womwe mwaphonya mukangokumbukira. Kenako dikirani osachepera maola 12 musanatenge mlingo wanu wotsatira wa colchicine.

Colchicine imatha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zizindikiro izi zili zazikulu kapena sizichoka:

• nseru
• kusanza
• kutsegula m'mimba
• kupweteka kwa m'mimba kapena kupweteka

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, siyani kumwa colchicine ndipo itanani dokotala nthawi yomweyo:

• kupweteka kwa minofu kapena kufooka
• dzanzi kapena kumva kulasalasa zala kapena kumapazi
• kuvulaza kapena kutuluka mwachilendo
• zilonda zapakhosi, malungo, kuzizira, ndi zizindikiro zina za matenda
• kufooka kapena kutopa
• kutuwa kapena imvi pamilomo, lilime, kapena makhwalala

Colchicine imatha kuchepetsa kubala mwa amuna. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito colchicine.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, pitani kuchipatala chapafupi kuchipatala mwachangu. Kutenga colchicine wambiri kumatha kubweretsa imfa.

Zizindikiro za bongo zingaphatikizepo:

• kupweteka m'mimba
• nseru
• kusanza
• kutsegula m'mimba
• kuvulaza kapena kutuluka mwachilendo
• zilonda zapakhosi, malungo, kuzizira, ndi zizindikiro zina za matenda
• kutuwa kapena imvi pamilomo, lilime, kapena makhwalala
• kupuma pang'ono
• kuchepa kapena kuyimitsa kugunda kwa mtima

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amatha kuyitanitsa mayeso ena a labu kuti muwone yankho lanu ku colchicine.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Zithunzi^®
• Gloperba^®